원발성 부갑상선항진증에 의한 악골의 다발성 갈색종양

Multiple brown tumors of the jaws in primary hyperparathyroidism

  • 김경아 (전북대학교 치의학전문대학원 구강악안면방사선학교실 및 구강생체과학연구소) ;
  • 고광준 (전북대학교 치의학전문대학원 구강악안면방사선학교실 및 구강생체과학연구소)
  • Kim, Kyoung-A (Department of Oral and Maxillofacial Radiology, School of Dentistry, and Institute of Oral Bio Science, Chonbuk National University) ;
  • Koh, Kwang-Joon (Department of Oral and Maxillofacial Radiology, School of Dentistry, and Institute of Oral Bio Science, Chonbuk National University)
  • 투고 : 2010.07.15
  • 심사 : 2010.08.05
  • 발행 : 2010.09.30

초록

Brown tumor is usually diagnosed at the terminal stage of hyperparathyroidism. Diagnosis of this tumor is confirmed by endocrinologic investigations along with clinical and radiographic examination. Radiographical differential diagnosis of this tumor includes central giant cell granuloma, aneurysmal bone cyst, metastatic tumor, multiple myeloma, and Paget disease. This report presents a rare case of multiple brown tumors occurring at the maxilla and mandible, which was initially misdiagnosed as central giant cell granuloma. Plain radiographs demonstrated multiple well-defined multilocular radiolucency. CT images showed soft tissue mass with low attenuated lesions, perforation of the lingual cortical plate, and a heterogeneous mass at the right thyroid lobe. These findings were consistent with parathyroid adenoma. The patient had hypercalcemia, hypophosphatemia, and elevated alkaline phosphatase level. Surgical excision of the tumor was performed. No recurrence was observed during a 28-month follow-up.

키워드

참고문헌

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