Journal of the Korean Institute of Oriental Medical Informatics (대한한의정보학회지)

The Korea Institute of Oriental Medical Informatics (대한한의정보학회)
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The Effect of seven Korean Traditional Herbal Medicines on 3T3-L1 Adipocyte Differentiation

한약재 추출물이 지방세포주 3T3-L1 분화에 미치는 영향

  • Kim, Ji-Seong (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Cho, Ga-Young (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Kim, Eun-Joo (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Park, Jun-Seong (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Rho, Ho-Sik (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Park, Hye-Yoon (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Kim, Duck-Hee (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER) ;
  • Kim, Han-Gon (Skin Research Institute, AMOREPACIFIC CORPORATION/R&D CENTER)
  • 김지성 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 조가영 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 김은주 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 박준성 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 노호식 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 박혜윤 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 김덕희 ((주)아모레퍼시픽 기술연구원 피부과학연구소) ;
  • 김한곤 ((주)아모레퍼시픽 기술연구원 피부과학연구소)
  • Published : 2009.09.25
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Abstract

Objectives : The aim of the present study is to evaluate the effects Rehmannia glutinosa, Radix puerariae, Semen coicis, Fructus hordei, Cortex acanthopanacis, Fructus chaenomelis, or Radix glycyrrhizae extracton 3T3-L1 preadipocytes differentiation. Methods : We adopted Oil Red O staining methods to observe the formed lipid droplets. And the amount of lipids in adipocytes was measured using absorptiometric analysis. Results : The extracts of Rehmannia glutinosa, Radix puerariae, Semen coicis, Fructus hordei, Cortex acanthopanacis, Fructus chaenomelis, or Radix glycyrrhizae stimulated the preadipocytes differentiation and lipid droplet formation. And the complex extract of the traditional herbal medicines stimulated there actions more than single extracts. Conclusions : The extract of Rehmannia glutinosa, Radix puerariae, Semen coicis, Fructus hordei, Cortex acanthopanacis, Fructus chaenomelis, or Radix glycyrrhizae has stimulatory effects. on adipogenesis. Moreover, the complex extract of the traditional herbal medicines has more effect than single extracts.

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