Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
권호 표지
DOI QR코드

DOI QR Code

Preparation and Emulsifying characteristics of Diethylene glycol succinate Derivative

에틸렌디글리콜과 숙신산 에스테르의 제조와 유화 특성

  • 이재덕 (충북대학교 공업화학과) ;
  • 정노희 (충북대학교 공업화학과)
  • Published : 2009.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

A reaction device raising a generation yield by efficiently removing water generated in an esterified reaction between diethylene glycol monoethyl ether and succinic acid with mixture of an azeotropic point was newly developed as a new product in development of more stabilized emulsifier with a semi-solid phase(cream) in an emulsified phase of interfacial activity. The bis-(diethylene glycol monoethyl ether succinate(hereinafter, called as BDGS) with a high yield of more than 95% was obtained. As this has a property containing amphoteric emulsified functions such as W/O type or O/W type, etc., and has a merit that can be used regardless of any emulsified phase, there is no need using other emulsified surfactant. therefore, as this has excellent skin wetability in the cosmetics industry, a product having a wider range in quality compatibility or cost saving, etc. as a humectant has been developed.

Keywords

References

  1. Wilkinson JB, Moore RJ, eds. Harry's Cosmeticology. New York: Chemical Publishing, 1982
  2. Rieger MM. Cosmetics and their relation to drugs. In: Swarbrick j, Boylan jC, eds. Encyclopedia of Pharmaceutical Technology, Vol. 3. New York:Marcel Dekker, 1990:361-3
  3. Martin A, Bustamante P, Chun ARC. Physical Pharmacy. Philadelphia: Lea &Febiger, 1993:393-396
  4. ICI Surfactants, Brochure 41-lE. Personal Care. Middlesbrough, Cleveland, United Kingdom, 1996
  5. Herzog B, Marquart D, Muller S, Pedrussio R, Sucker H. Einfluss von zusammensetzung und Phasenverhaltnis auf die konsistenz von cremes. Pharm Ind, 1998 ;60 ;713-721
  6. Chiamori. H.C, Brown. J.W, Adhiprakasha. E.V and hantsoo. E.T, Suspension ofnanoparticles in SU-8: Processing and characterization of nanocompositepolymer, Microelectr J, 39, 228 (2008)
  7. Klaus Kunath, Pavia Kopekova, Tamare Minko and jindich Kopeek, HPMAcopolymer-anticancer drug -OV -TL16 antibody conjugates. 3. The effect of freeof free and polymer-bound Adriamycin on the expession of somgenes in theOVCAR-3 human ovarian carcinoma cell line, Eur J Pharm Biopharms, 49, 11(2000) https://doi.org/10.1016/S0939-6411(99)00033-8
  8. Fernanda S. Poletto, Eliezer jager, Leticia Cruz, Adriana R. Pohlmann and Silvia S. Guterres, The effext of polymeric wall on the permeability of drug-loadednanocapsules, MSE, 28, 472 (2008)
  9. Ourique. A. F, Pohlmann. A. R, Guterres. S. S and Beck. R. C. R, Tretinoin-loaded nanocapsules: preparation, physicochemical characterization, and photostability study, Int J Pharm, 352, 1 (2008)
  10. Leticia Sias da Fonseca, Rodrigo Paulo Silveira, Alberto Marc;al Deboni, Edilson Valmir Benvenutti, Tania M.H. Costa, Silvia S. Guterres and Adriana R. Pohlmann, Nanocapsules@xerogel micro microparticles containing sodium diclofenac: A new strategy to control the release of drugs, Int J Pharm, 15, 328 (2008)
  11. Alberto Gabizon, Hilary Shmeeda, Aviva T. Horowitz and Samuel Zalipsky, Tumor cell targeting of iposome-entrapped drugs with phospholipid-anchored folic acidPEG conjugates, Adv Drug Deliv Rev, 56, 1177 (2004) https://doi.org/10.1016/j.addr.2004.01.011
  12. jong-Moon jeong, Yong-Chan Chung and ji-Hwan Hwang, Enhanced adjucantic property of polymerized loposome as compared to a phospholipid liposome, J Biotechnol, 94, 255 (2002) https://doi.org/10.1016/S0168-1656(01)00430-8
  13. Qiu. L.X, Yao. B, Ding. Z.H, Zheng. Y.J, jia. X.P and Zheng. W.t, characterization of structure and properties of TiN-TiB2 nano-compositeprepared by ball milling and high pressure heat treatment, J. Alloys andCompounds, 456, 436 (2008) https://doi.org/10.1016/j.jallcom.2007.02.052
  14. Muller, R, H. and peters, K, Nanosuspensions for the formulation ofpoorly soluble drugs. I.Preparation by a size-reduction technique, Int J Pharm,160, 229(1998) https://doi.org/10.1016/S0378-5173(97)00311-6
  15. Ford, F, Woolfe, J. and Florence, A, nanospheres of cyclosporine A: Poor oralacsorp-tion in dog, Int J Pharm, 183, 3 (1999)
  16. Corinne Erni, Catherine Suard, Sergio Freitas, Donatus Dreher, Hans P. Merkle and Elke Walter, Evaluation of cationic solid lipid microparicles as syntheticcarriers for the targeted delivery of macromolecules to phagocytic andtigenpresenting celles, Biomaterials, 12, 4667 (2002)
  17. Yuan Yuan, Yanxiang Gao, jian Zhao and Like Mao, Characterization andstability evaluation of l3-carotene nanoemulsions prepared by high pressure homogenization under various emulsifying conditions, Food Res Int, 41, 61 (2008) https://doi.org/10.1016/j.foodres.2007.09.006
  18. jeanne C. Stachowiak, Marcio G. von Muhlen, Thomas H. Li, Laleh Jalilian,Sapun H. Parekh and Daniel A. Fletcher, Piezoelectric control of needle-freetransdermal drug delivery, J Control Release, 124, 88 (2007) https://doi.org/10.1016/j.jconrel.2007.08.017
  19. Annette zur Miihlen, Cora Schwarz and Wolfgang Mehnert, Solid lipidnanoparticles (SLN) for controlled drug delivery-Drug release and releasemechanism, Eur J Pmrms Biophann, 45, 149 (1998)
  20. Totik. Y and Gzvgali. M, The effect of homogenization treatment on the hot workability between the surface and the center of AA 2014 ingots, Materials Character, 49, 261 (2002) https://doi.org/10.1016/S1044-5803(03)00030-5
  21. Morel. S, Terreno. E, Ugazio. E, Aime. S and Gasco. M. R, NMR relaxometricinvestigations of solid lipid manoparticles (SLN) containing gadoli-nium (m)complexe, Eur J Phann Biopmrrn, 45, 157 (1998)
  22. Heiati. H, Tawashi. R, Shivers. R. Rand Phillipps. N.C, Solid lipid nanoparticles as drug carriers. I. Incorporation and retention of the lip-ophilic prodrug3' -azido-3' -deoxythymidine palmitat, Int J Pmnn, 146, 123 (1997)
  23. Yang. S.C, Lu. L.F, Cai. Y, Zhu. J. B, Liang. B. Wand Yang. C. Z, Bodydistribution III mice and targetiong effect on brai, J Control Release, 59, 299(1999) https://doi.org/10.1016/S0168-3659(99)00007-3
  24. Jieming Gao, Jing Ming, Bin He, Yujiang Fan, Zhongwei Gu and Xingdong Zhang, Preparation and characterization of novel polymeric micelles for 9-nitro-20(S)camptothecin delivery, Eur J Pmnn , 23, 121 (2008)
  25. Martinez-Sancho. C, Herrero-Vanrell. R and Negro.S, Vitamin A palmitate and aciclovir biodegradable microspheres for intraocular sustained release, Int J Pmnn, 326, 100 (2006)
  26. Ju Yeol LEE, Young Koo PARK, Joon Seok PARK, Seung Ho KIM, J ae Churl Ko, Young Min JO, Ambient adsorption of C02 using inorganic sorbent, J Kor Oil Chern, 24, 92 (2007)
  27. Y. C. Kim, Analysis of Benzoxazolo Carbocyanine Compound using F AB/Mass Spectrometry, J Kor Oil Chern Soc, 23(2),125 (2006)
  28. C. H. Park, S. J. Kim, Y. G. Kim, H. S. Park, Synthesis of Silicon Softner for Permanent Press Finish and Its Characterization, J Kor Oil Chern Soc, 12(1), 29 (1995)
  29. G. Y. Yoo, J. H. Kim, H. S. Park, and Y. G. Kim, Synthesis of Modified Polyesters Containing Triphosphorus for FlameRetardant Coatings, J Kor Oil Chern Soc, 23(3), 287 (2007)