Sleep Medicine and Psychophysiology (수면정신생리)

KOREAN ACADEMY OF SLEEP MEDICINE (대한수면의학회)
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Respiratory Sleep Physiology

수면 호흡 생리

  • Kim, Jin-Woo (Division of Pulmonary, Critical care, and Sleep medicine, Department of Internal Medicine, The Catholic University of Korea, College of Medicine) ;
  • Lee, Sang-Haak (Division of Pulmonary, Critical care, and Sleep medicine, Department of Internal Medicine, The Catholic University of Korea, College of Medicine)
  • 김진우 (가톨릭대학교 의과대학 내과학교실) ;
  • 이상학 (가톨릭대학교 의과대학 내과학교실)
  • Published : 2009.06.30
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Abstract

Regulation of respiration differs significantly between wakefulness and sleep. Respiration during wakefulness is influenced by not only automatic control but also voluntary and behavioral control. Sleep is associated with definite changes in respiratory function. With the onset of sleep, voluntary control of ventilation that overrides automatic control during wakefulness becomes terminated. Also ventilatory response to various stimuli including hypoxemia and hypercapnia is decreased. With these reasons respiration during sleep becomes fragile and unstable so that marked hypoxemia can be happened in patients with lung disease especially during REM sleep. Obstructive sleep apnea may also be developed if upper airway resistance is increased in addition to these blunted ventilatory responses.

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