Acrylamide concentration in domestic foods

국내에서 유통된 식품의 아크릴아마이드 함량 분석

  • Kim, Mi-Kyo (Department of Food Science and Technology, Ewha Womans University) ;
  • Oh, Mi-Hwa (National Institute of Animal Science, Rural Development Administration) ;
  • Youn, Soo-Hyun (Department of Food Science and Technology, Ewha Womans University) ;
  • Kim, Cheong-Tae (Research and Development Center) ;
  • Sung, Dong-Eun (Department of Food Science and Technology, Ewha Womans University) ;
  • Ham, Jun-Sang (National Institute of Animal Science, Rural Development Administration) ;
  • Choi, Dong-Mi (Food Chemical Residues Division, Korea Food & Drug Administration) ;
  • Oh, Sang-Suk (Department of Food Science and Technology, Ewha Womans University)
  • 김미교 (이화여자대학교 식품공학과) ;
  • 오미화 (농촌진흥청 국립축산과학원 축산물이용과) ;
  • 윤추현 (이화여자대학교 식품공학과) ;
  • 김청태 ((주)농심 개발본부 식품분석팀 R&D) ;
  • 성동은 (이화여자대학교 식품공학과) ;
  • 함준상 (농촌진흥청 국립축산과학원 축산물이용과) ;
  • 최동미 (식품의약품안전청 화학물질과) ;
  • 오상석 (이화여자대학교 식품공학과)
  • Published : 2009.09.30

Abstract

Acrylamide in various food samples in Korea were monitored during the period beginning August 2006 through May 2007. A total of 471 food products that were purchased at local markets were categorized into 17 groups and analyzed for the acrylamide content by using an LC-MS/MS method. Food samples that were selected based on special consideration such as expert consultation, Korean food consumption data and food market shares were considered to be representative. There are very large variations in acrylamide levels within tested foods. Acrylamide content ranged from ND(not detected) to $4,002{\mu}g$/kg with all tested samples. Acrylamide levels are relatively high in 'cereal', 'coffee', 'potato snacks', 'biscuit', 'chocolate', and 'prune juice'. Acrylamide was also detected in fruits, vegetables, Korean traditional cookies which are considered as safe for acrylamide.

많은 산업체와 실험실에서 사용되고 있는 공업용 화학물질인 아크릴아마이드는 발암유발가능성이 있는 것으로 알려져 있으며, 국내 외 모니터링 결과 감자, 밀 등 고탄수화물 식품을 고온에서 조리,가공한 식품에서 많이 검출되는 것으로 알려져 있다. 아크릴아마이드의 위해평가를 위해서는 식품 내 아크릴아마이드 함량 및 식이노출평가 등의 기초자료가 절실히 요구되나 우리나라는 제 외국에 비해 식품 내 아크릴아마이드 관한 데이터베이스가 미약한 편이다. 이에 본 연구는 국내 유통식품의 모니터링을 통해 아크릴아마이드의 국내 실태를 파악하기 위해 수행 되었다. 모니터 링을 위해 우리나라에서 많이 섭취한 식품을 중심으로 국내 food market shares 등의 통계를 이용하여 17개 식품군에서 470여 개의 시료를 선정하였으며, 이를 FDA의 LC-MS/MS 방법으로 분석하였다. 모니터링 결과, '감자스낵류', '비스킷류', '시리얼류', '초콜릿류', '커피류','prune juice' 등에서 비교적 많은 양의 아크릴 아마이드가 검출되었으며, 각 식품군의 검출수준은 감자스낵류 $195{\sim}4,002ppb$, 비스킷류 $ND{\sim}681ppb$, 시리얼류 $79{\sim}233ppb$, 초콜릿류 $ND{\sim}447ppb$, 커피류 $ND{\sim}681ppb$, prune juice 366ppb로 이는 이전 국내외 분석결과와 비슷한 수치이다. 그러나 지금까지 아크릴아마이드 문제와 관련해서 안전하다고 인식되어 온 과일, 채소류, 해조류, 한과류에서도 아크릴아마이드가 검출됨으로 인해 이들 식품군도 조리방법에 따라서 식이를 통한 아크릴아마이드 노출원이 될 수 있음이 확인되었다. 그 외의 껌, 잼류, 두부류 또는 묵류, 포도씨유, 주류, 건포류에서는 아크릴아마이드가 검출되지 않았다. 본 연구의 결과는 우리나라의 실정에 맞는 아크릴아마이드의 위해 평가를 위한 기초자료로서 사용 될 수 있을 것으로 사료된다.

Keywords

References

  1. Giese J.: Acrylamide in Foods. Food Teehnol, 5. 8-9 (2002)
  2. Simonne H, Archer L.: Acrylamide in Foods: A review and Update. Available from: http://edis.ifas.ufi.edu/FY578,Accessed June, 30. 2007
  3. Smith EA, Oeheme FW.: Acrylamide and polyacrylamide: A review of production, use, environmental fate and neurotoxicity. Rev. Environ. Health, 9, 215-228 (1991)
  4. Taeymans D, Wood J, Ashby P, Blank I, Studer A, Stadler RH, Gonde P, Van Eijck P, Lalljie S, Lingnert H, Lindblom M, Matissek R, Muller D, Tallmadge D, O' Brien J, Thompson S, Silvani D, Whitmore T.: A review of acrylamide: An industry perspective on research, analysis, formation and control, Crit. Rev. Food Sci. Nutri., 44, 323-347 (2004) https://doi.org/10.1080/10408690490478082
  5. International Agency for Research on Cancer (IARC), Monographs on the valuation of carcinogen risk to humans: Some Industrial Chemicals, 60, 389 (1994)
  6. Swedish National Food Administration (SNFA), Information about acrylamide in food (includes 24th April 2002 press release). (2002)
  7. Janneke G Hogervorst, Leo J Schouten, Erik J Konings, R Alexandra Goldbohm, Piet A van den Brandt.: Dietary acrylamide intake and the risk of renal cell, bladder, and prostate cancer. Am. J. Clin. Nutr., 87,1428-1438 (2008)
  8. Lorelei A. Mucci, Kathryn M. Wilson.: Acrylamide Intake through Diet and Human Cancer Risk. J. Agrie. Food Chern., 56, 6013-6019 (2008) https://doi.org/10.1021/jf703747b
  9. Tareke E, Rydberg P, Karlsson P, Eriksson S, Tornqvist M.: Acrylamide: A cooking Carcinogen? Chern. Res. Toxieol., 13, 517 -522 (2000) https://doi.org/10.1021/tx9901938
  10. Tareke E, Rydberg P, Karlsson P.: Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J. Agrie. Food Chem., 50, 4998-5006 (2002) https://doi.org/10.1021/jf020302f
  11. Konings EJ, Baars AJ, van Klaveren JD, Spanjer MC, Rensen PM, Hiemstra M, van Kooij JA, Peters PW.: Acrylamide exposure from foods of the Dutch population and an assessment ofthe consequent risks. Food Chern. Toxieol., 41, 1569-1579 (2003) https://doi.org/10.1016/S0278-6915(03)00187-X
  12. Al-Dmoor, HM.: Determination of acrylamide levels in selected traditional foodstuffs and drinks in Jordan. J. Food Agrie. Environ., 3, 77-80 (2005)
  13. Eerola S, Hollebekkers K, Hallikainen A, Peltonen K.: Acrylamide levels in Finnish foodstuffs analysed with liquid chromatography tandem mass Spectrometry. Mol. Nutr. Food Res., 51, 239-247 (2007) https://doi.org/10.1002/mnfr.200600167
  14. European Chemicals Bureau, European Commission. European Union Risk Assessment Report: Acrylamide. Available from: http://ecb.jrc.it/DOCUMENTS/Existing-Chemicals/R1SK _ ASSESSMENT /REPORT/acrylamidereport011.pdf, Accessed June, 30. 2007
  15. Federal Institute for Risk Assessment (BfR), Assessment of acrylamide intake from foods containing high acrylamide levels in Germany, Available from http://www.bfr.bund.de/cml245/ assessment_of acrylamide intake_from foods_containing_high_acrylamide levels_in_germany.pdf, Accessed June, 30. 2007
  16. Food and Drug Administration (FDA), Acrylamide in food. Available from: http://www.cfsan.fda.gov/-lrd/pestadd.html# acrylamide, Accessed June, 30. 2007
  17. Food and Drug Administration (FDA). Estimating dietary intake of substances in food. Available from: http://www.cfsan.fda.gov/-dms/opa2cg8.html, Accessed June, 30. 2007
  18. Food and Agriculture Organization of the United Nations / World Health Organization (FAO/WHO). Summary and conclustions of the sixty-fourth meeting of Joint FAO/WHO expert committee on food additives (JECFA). Available from;ftp://ftp.fao.org/es/esn/jecfa/jecfa64_summary.pdf
  19. Hilbig A. Freidank N, Kersting M, Wilhelm M, Wittsiepe J.: Estimation of the dietary intake of acrylamide by German infants children and adolescents as calculated from dietaryrecords and available data on acrylamide levels in food group. J. Hyg. Environ. Health, 207, 463-471 (2004) https://doi.org/10.1078/1438-4639-00317
  20. Kim CT, Hwang ES, Lee HJ.: Analysis of acyl amide in processed foods obtained from korean markets. J. Food Hyg. Safety, 20,191-198 (2005)
  21. Koh BK.: Determination of acrylamide content offood products in Korea. J. Sci. Food Agric., 86, 2587-2591 (2006) https://doi.org/10.1002/jsfa.2652
  22. Lee MS, Park JY, Oh SS.: Acrylamide monitoring in homemade food products. Korean J. Soc. Food Cookery Sci., 20, 708-711 (2004)
  23. Lineback D, Wenzl T, Ostermann OP. de la Calle B, Anklam E. & Taeymans D.: Overview of acrylamide monitoring databases. J. AOAC Int., 88, 246-252 (2005)
  24. Matthys C, Bilau M, Govaert Y, Moons E, Henauw SDe, Willems JL.: Risk assessment of dietary acrylamide intake in Flemish adolescents. Food Chern. Toxicol., 43, 271-278 (2005) https://doi.org/10.1016/j.fct.2004.10.003
  25. Office of Environmental Health Hazard Assessment (OEHHA). Characterization of Acrylamide Intake from Certain Foods. Available from: www.oehha.ca.gov. Accessed June, 30. 2007
  26. Park JY.: Acrylamide Monitoring of Domestic Heat-Treated Food Products, MS thesis, Ewha Womans University, Seoul, Korea (2003)
  27. Park JY, Kim CT, Kim HY, Keum EH, Lee MS, Chung SY, Sho YS, Lee JO, Oh SS.: Acrylamide Monitoring of Domestic Food Products. Korean J. Food Sci. Technol., 36, 872-878 (2004)
  28. Swedish National Food Agency (SNFA). Acrylamide in food: Acrylamide in food stuffs, consumption and intake. Available from htp://www.slv.se/engdefault.asp. Accessed June, 30. 2007
  29. Svensson K, Abramsson L, Becker W, Glynn A, Hellenas KE, Lind Y, Rosen J.: Dietary intake of acrylamide in Sweden. Food Chern. Toxicol., 41, 1581-1586 (2003) https://doi.org/10.1016/S0278-6915(03)00188-1
  30. Tateo F, Bononi M, Andreoli G.: Acrylamide levels in cooked rice, tomato sauces and some fast food on the Italian market. J. Food Compo Anal., 20, 232-235 (2007) https://doi.org/10.1016/j.jfca.2006.06.006
  31. The Food and Public Health Branch of the Food and Environmental Hygiene Department of the Government of the Hong Kong Special Administrative Region
  32. Risk Assessment Studies Report (No.11): Chemical Hazard Evaluation Acrylamide in Food. Available from: http://www.fehd.gov.hk/safefood/report/acrylamide/ras_acrylamide_2.pdf, Accessed June, 30. 2007
  33. United Kingdom Food Standards Agency (UK FSA), Analysis of total diet study samples for acrylamide. Available from; http://www.foodstandards.gov.uk/multimedia/pdfs/fsis712005.pdf, Accessed June, 30, 2007
  34. Yoshida M, Ono H, Chuda Y, Yada H, Ohnishi-Kameyama M, Kobayashin H, Ohara-Takada A, Matsuura-Endo C, Mori M, Hayashi N, Yamaguchi Y.: Acrylamide in Japanese Processed Foods and Factors Affecting Acrylamide Level in Potato Chips and Tea. Adv. Exp. Med Bioi., 561, 405-413 (2005) https://doi.org/10.1007/0-387-24980-X_31
  35. KMHW. Report on 2001 national health and nutrition survey Ministry of Health & Welfare. Nutrition survey. Gyeonggi. Korea (2001)
  36. Monthly food journal. A yearbook of food circulation. Monthly food journal. Seoul (2006)