The Effect of Body Wash Containing Triclosan and Bamboo Salt on Axillary Malodor

Triclosan과 죽염을 함유한 바디워시의 액취 등에 미치는 효과에 대한 연구

  • Roh, Seok-Sun (Daejeon University, College of Oriental Medicine, Department of Oriental Medicine) ;
  • Yun, Woo-Sik (Daejeon University, College of Oriental Medicine, Department of Oriental Medicine) ;
  • Jung, Ji-Young (Daejeon University, College of Oriental Medicine, Department of Oriental Medicine) ;
  • Yu, Hyung-Uk (Daejeon University, College of Oriental Medicine, Department of Oriental Medicine) ;
  • Hwang, Dong-Sung (Daejeon University, College of Oriental Medicine, Department of Oriental Medicine) ;
  • Choi, Seung-Man (LG Household & Health Care R&D Institute) ;
  • Lee, Jeong-Rae (LG Household & Health Care R&D Institute) ;
  • Kang, Sang-Jin (LG Household & Health Care R&D Institute) ;
  • Chang, Sug-Youn (LG Household & Health Care R&D Institute)
  • 노석선 (대전대학교 한의과대학) ;
  • 윤우식 (대전대학교 한의과대학) ;
  • 정지영 (대전대학교 한의과대학) ;
  • 유형욱 (대전대학교 한의과대학) ;
  • 황동성 (대전대학교 한의과대학) ;
  • 최승만 (LG생활건강 기술연구원) ;
  • 이정래 (LG생활건강 기술연구원) ;
  • 강상진 (LG생활건강 기술연구원) ;
  • 장석윤 (LG생활건강 기술연구원)
  • Published : 2009.09.30

Abstract

This study was performed to evaluate a deodorant body wash with 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, which have an inhibitory effect on axillary malodor. In this studies, in vitro antibacterial study and the clinical study, which was designed by randomized assignment, double-blind and cross-over, were performed. In the antibacterial study, test sample, which was body wash having 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, have a potent antibacterial effect on Corynebacterium glutamicum, Corynebacterium xerosis, Corynebacterium jeikeium. In the clinical study, test sample has a potent and significant deodorizing effect on axillary malodor and an antibacterial efficacy. And its efficacy was maintained for 9 h at least. There was no side effect during the period of clinical study. Consequently, body wash, containing 1.0 wt% of triclosan and 0.4 wt% of bamboo salt, has the effectiveness and the safety about axillary malodor reduction.

1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시의 액취 등에 미치는 효과에 대한 연구를 위하여 in vitro 항균시험 및 무작위 배정, 이중맹검, 교차설계로 진행한 임상시험을 실시하였다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 Corynebacterium glutamicum, Corynebacterium xerosis, Corynebacterium jeikeium를 균주로 한 in vitro 항균 실험에서 모두 우수한 항균 효과가 있었다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액취를 전반적으로 유의성 있게 감소시켰고 그 효과는 최소 9 h 동안 지속되었다. 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액와 균수를 유의성 있게 감소시켰고 그 효과는 최소 9 h 동안 지속되었다. 임상시험 기간 동안 피시험자 전체에서 이상반응 증상은 나타나지 않았다. 결론적으로 1.0 wt% triclosan과 0.4 wt% 죽염을 함유한 바디워시는 액취에 대한 감소효과와 피부 안전성이 우수하였다.

Keywords

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