Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Etiologic and Immunologic Characteristics of Thoroughbred Horses with Bacterial Infectious Upper Respiratory Disease at the Seoul Race Park

  • Ryu, Seung-Ho (Korea Racing Authority) ;
  • Koo, Hye-Cheong (KRF Zoonotic Disease Priority Research Institute, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University) ;
  • Park, Young-Kyung (Department of Microbiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University) ;
  • Kim, Jun-Man (Department of Microbiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University) ;
  • Jung, Woo-Kyung (Department of Microbiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University) ;
  • Davis, William C. (Department of Veterinary Microbiology and Pathology, Washington State University) ;
  • Park, Yong-Ho (Department of Microbiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University) ;
  • Lee, Chang-Woo (Department of Clinical Pathology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University)
  • Published : 2009.09.30
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Abstract

Equine respiratory disease is a common cause of poor performance and training interruptions. The higher incidence rate of infectious upper respiratory disease (IURD) in thoroughbred racehorses at the Seoul Race Park coincided with the frequent stabling season, shorter stabling periods, and younger ages in this study. Incidence rates were also correlated with significantly lower proportions of cells expressing MHC class II-, CD2 antigen-, $CD4^+$- or $CD8^+$-T lymphocyte-, and B lymphocyte in IURD patients compared with healthy control groups in the summer and fall and in 2-and-3-year-old groups. The data suggested that movement and new environments may have resulted in immunosuppression and inappropriate responses to respiratory pathogens in IURD patients. The IURD incidence decreased with age, perhaps by the acquisition of immunity, and study results suggested that immunologic protection was associated with IURD, particularly in young thoroughbred racehorses. Streptococci isolates were identified in 11 of 72 IURD horses, and 3 of these isolates were identified as Streptococcus. equi subsp. equi. S. equi subsp. zooepidemicus was isolated from 2 of 23 IURD horses in the spring (8.7%), 5 of 23 in the summer (21.7%), and 1 of 6 in winter (16.7%). S. equi subsp. zooepidemicus (5%) was also identified in 3 of 61 isolates from clinically normal horses. Racetracks should implement anti-IURD protective measures by assessing the capacity of equine immunologic protection at the Park and by limiting the introduction of specific respiratory pathogens (such as S. equi subsp. equi) by preventing the access of infected but subclinical horses with a specified respiratory pathogen-free certification system prior to Park entry.

Keywords

References

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