Parasites, Hosts and Diseases

  • 제47권3호
  • /
  • Pages.269-273
  • /
  • 2009
  • /
  • 2982-5164(pISSN)
  • /
  • 1738-0006(eISSN)
대한기생충학·열대의학회 (The Korea Society for Parasitology and Tropical Medicine)
권호 표지
DOI QR코드

DOI QR Code

A Locally Acquired Falciparum Malaria via Nosocomial Transmission in Korea

  • Kim, Jung-Yeon (Division of Malaria and Parasitic Disease, Korea Centers for Disease Control and Prevention (KCDC)) ;
  • Kim, Jeong-Su (Pusan National University Yangsan Hospital) ;
  • Park, Mi-Hyun (Department of Biological Sciences, Inha University) ;
  • Kang, Young-A (Division of Epidemic Intelligence Service of KCDC) ;
  • Kwon, Jun-Wook (Division of Communicable Diseases of KCDC) ;
  • Cho, Shin-Hyeong (Division of Malaria and Parasitic Disease, Korea Centers for Disease Control and Prevention (KCDC)) ;
  • Lee, Byeong-Chul (Division of Malaria and Parasitic Disease, Korea Centers for Disease Control and Prevention (KCDC)) ;
  • Kim, Tong-Soo (Department of Parasitology, College of Medicine, Inha University) ;
  • Lee, Jong-Koo (Director, KCDC)
  • 발행 : 2009.09.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A 57-year old man who was admitted to an emergency room of a tertiary hospital with hemoptysis developed malarial fever 19 days later and then died from severe falciparum malaria 2 days later. He had not traveled outside of Korea for over 30 years. Through intensive interviews and epidemiological surveys, we found that a foreign patient with a recent history of travel to Africa was transferred to the same hospital with severe falciparum malaria. We confirmed through molecular genotyping of the MSP-1 gene that Plasmodium falciparum genotypes of the 2 patients were identical. It is suggested that a breach of standard infection control precautions resulted in this P. falciparum transmission between 2 patients in a hospital environment. This is the first report of a nosocomial transmission of falciparum malaria in Korea.

키워드

참고문헌

  1. Centers for Disease Control and Prevention, Republic of Korea. http://stat.cdc.go.kr/
  2. Abulrahi HA, Bohlega EA, Fontaine RE, al-Seghayer SM, al-Ruwais AA. Plasmodium falciparum malaria transmitted in hospital through heparin locks. Lancet 1997; 349: 23-25 https://doi.org/10.1016/S0140-6736(96)03508-8
  3. Alweis RL, DiRosario K, Conidi G, Kain KC, Olans R, Tully JL. Serial nosocomial transmission of Plasmodium falciparum malaria from patient to nurse to patient. Infect Control Hops Epidemiol 2004; 25: 55-59 https://doi.org/10.1086/502293
  4. Jain SK, Persaud D, Perl TM, Pass MA, Murphy KM, Pisciotta JM, Scholl PF, Casella JF, Sullivan DJ. Nosocomial malaria and saline flush. Emerg Infect Dis 2005; 11: 1097-1099 https://doi.org/10.3201/eid1107.050092
  5. Moro ML, Romi R, Severini C, Casadio GP, Sarta G, Tampieri G, Scardovi A, Pozzetti C, Maria Outbreak Group. Patient-to-patient transmission of nosocomial malaria in Italy. Infect Control Hops Epidemiol 2002; 23: 338-341 https://doi.org/10.1086/502062
  6. Centers for Disease Control and Prevention, Republic of Korea. Communicable Diseases Monthly Report. CDMR 2007; 6 (No. 52)
  7. Lee WJ, Klein TA, Kim HC, Choi YM, Yoon SH, Chang KS, Chong ST, Lee IY, Jones JW, Jacobs JS, Sattabongkot J, Park JS. Anopheles kleini, Anopheles pullus, and Anopheles sinensis: potential vectors of Plasmodium vivax in the Republic of Korea. J Med Entomol 2007; 44: 1086-1090 https://doi.org/10.1603/0022-2585(2007)44[1086:AKAPAA]2.0.CO;2
  8. Shin EH, Kim TS, Lee HW, Lee JS, Lee WJ. Vector competence of Anopheles lesteri Baisas and Hu (Diptera: Culicidae) to Plasmodium vivax in Korea. Korean J Parasitol 2002; 40: 41-44 https://doi.org/10.3347/kjp.2002.40.1.41
  9. Shin EH, Lee WJ, Lee HI, Lee DK, Klein TA. Seasonal population density and daily survival of anopheline mosquitoes (Diptera: Culicidae) in a malaria endemic area, Republic of Korea. J Vector Ecol 25; 30: 33-40
  10. Snounou G, Viriyakosol S, Zhu XP, Jarra W, Pinheiro L, do Rosario VE, Thaithong S, Brown KN. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol 1993; 61: 315-320 https://doi.org/10.1016/0166-6851(93)90077-B
  11. Kaneko O, Kimura M, Kawamoto F, Ferreira MU, Tanabe K. Plasmodium falciparum: allelic variation in the merozoite surface protein 1gene in wild isolates from southern Vietnam. Exp Parasitol 1997; 86: 45-57 https://doi.org/10.1006/expr.1997.4147
  12. Thompson JD, Gibson, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL_X windows interface: flexible strategies for multiple sequence. Nucleic Acids Res 1997; 24: 4876-4882
  13. Babinet J, Gay F, Bustos D, Dubarry M, Jaulmes D, Nquyen L. Transmission of Plasmodium falciparum by heart transplantation. Transplant Proc 1991; 303: 1515-1516 https://doi.org/10.1136/bmj.303.6816.1515
  14. Crafa F, Gugenheim J, Fabiani P, Di Marzo L, Militerno G, Iovine L, Goubaux B, Mouiel J. Possible transmission of malaria by liver transplantation. Transplant Proc 1991; 23: 2664
  15. Lattau LA. Nosocomial transmission and infection control aspects of parasites and ectoparasitic diseases. Part II. Blood and tissue parasites. Infect Control Hops Epidemiol 1991; 12: 111-121 https://doi.org/10.1086/646297
  16. Ferreira MU, Ribeiro WL, Tonon AP, Kawamoto F, Stephen MR. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP-1) of Plasmodium falciparum. Gene 2003; 304: 65-75 https://doi.org/10.1016/S0378-1119(02)01180-0
  17. Kerr PJ, Ranford-Cartwright LC, Walliker D. Proof of intragenic recombination in Plasmodium falciparum. Mol Biochem Parasitol 1994; 66: 241-248 https://doi.org/10.1016/0166-6851(94)90151-1
  18. Tanabe K, Sakihama N, Walliker D, Babiker H, Abdel-Muhsin AA, Bakote'e B, Ohmae H, Arisue N, Horii T, Rooth I, Farnert A, Bjorkman A, Ranford-Cartwright L. Allelic dimorphism-associated restriction of recombination in Plasmodium falciparum MSP1. Gene 2007; 397: 153-160 https://doi.org/10.1016/j.gene.2007.04.033

피인용 문헌

  1. International Travel and Imported Parasitic Diseases vol.30, pp.3, 2009, https://doi.org/10.7599/hmr.2010.30.3.156
  2. The use of multidose vials and fingerstick blood sampling devices in Korean emergency departments and intensive care units vol.18, pp.1, 2009, https://doi.org/10.1111/j.1440-172x.2011.01994.x
  3. On Taking a Different Route: An Unlikely Case of Malaria by Nosocomial Transmission vol.65, pp.8, 2009, https://doi.org/10.1093/cid/cix520