The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지

Randomized Clinical Controlled Trials with Herbal Acupuncture (Pharmacopuncture) in Korea - A Systematic Review

무작위 배정 비교 임상 시험을 통한 국내의 약침 연구에 대한 체계적 고찰

  • Park, Bong-Ky (Department of Liver-Immunity in Oriental Medicine College, Daejeon University) ;
  • Cho, Jung-Hyo (Department of Liver-Immunity in Oriental Medicine College, Daejeon University) ;
  • Son, Chang-Gue (Department of Liver-Immunity in Oriental Medicine College, Daejeon University)
  • 박봉기 (대전대학교 한의과대학 간장면역학교실) ;
  • 조정효 (대전대학교 한의과대학 간장면역학교실) ;
  • 손창규 (대전대학교 한의과대학 간장면역학교실)
  • Published : 2009.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: By assessing the quality of methodology and synthesis of results of RCTs (Randomized Controlled Clinical Trials) with herbal acupuncture (pharmacopuncture), we hope to help with administrating herbal acupuncture therapy in clinic and conducting RCT with herbal acupuncture. Methods: Reports of RCT conducted in Korea published in medical journals until February 2009 were collected. We surveyed elementary information of RCTs, evaluated randomization, double-blinding, allocation concealment and put together the results of RCTs by seven clinical topics. Results: 38 RCTs with herbal acupuncture were selected, then adequate methods for randomization and allocation concealment were found in 39% and 5% of studies. Complete double-blinding and a clear accounting of all participants were conducted in 42% and 50% of reports. The synthesis of RCTs revealed that herbal acupuncture was useful and effective on degenerative gonarthritis, omarthralgia on cerebrovascular accident, acute ankle sprain, back sprain, neck sprain, headache, rheumatoid arthritis and tennis elbow, generally. Conclusions: Although further improvement in quality of methodology of RCTs with herbal acupuncture is required, clinical usefulness of herbal acupuncture was shown especially on disorders of musculoskeletal system via RCTs.

Keywords

References

  1. Lee JY, Han YJ, Kim JH, Kim YJ, Kwon KR. Type analysis of Pharmacopuncture papers published in the Journal of Korean Institute of Pharmacopuncture. J Korean Institute of Herbal Acupuncture. 2006;9(3):147-54.
  2. Baik SI, Ahn JC, Kim YJ, Kim HS, Kwon KR. Type Analysis of Pharmacopuncture Papers Published in the Journal of Korean Acupuncture and Moxibustion. J Korean Acupuncture & Moxibustion Society. 2006;23(6):19-27.
  3. Akobeng AK. Understanding randomised controlled trials. Arch Dis Child. 2005;90(8):840-4. https://doi.org/10.1136/adc.2004.058222
  4. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17(1):1-12. https://doi.org/10.1016/0197-2456(95)00134-4
  5. Juni P, Altman DG, Egger M. Systematic reviews in health care: Assessing the quality of controlled clinical trials. BMJ. 2001;323(7303):42-6. https://doi.org/10.1136/bmj.323.7303.42
  6. Moher D, Schulz KF, Altman D. The CONSORT Statement: revised recommendations for improving the quality of reports of parallel-group randomized trials 2001. Explore (NY). 2005;1(1):40-5. https://doi.org/10.1016/j.explore.2004.11.001
  7. Clarke M, Oxman Ad. Cochrane Reviewers’ Handbook. ed. Oxford, UK: The Cochrane Library. 2001.
  8. The Centre for Reviews and Dissemination. 2009;33-42. Available at:URL:http://www.york. ac.uk/inst/crd/pdf/Systematic_Reviews.pdf. Accessed June 6, 2009.
  9. Montenegro R, Needleman I, Moles D, Tonetti M.Quality of RCTs in periodontology--a systematic review. J Dent Res. 2002;81(12):866-70. https://doi.org/10.1177/154405910208101214
  10. Hill CL, LaValley MP, Felson DT. Discrepancy between published report and actual conduct of randomized clinical trials. J Clin Epidemiol. 2002;55(8):783-6. https://doi.org/10.1016/S0895-4356(02)00440-7
  11. Park JE, Kang KW, Choi SM. Assessing Methodological Quality of Acupuncture Clinical Trials of Korea. J Korean Acupuncture & Moxibustion Society. 2007;24(1):127-35.
  12. Kim HB, Lee RM, Lee MH, Choi YS, Kim JI, Lee YH, et al. Comparative Study of Effects of ‘Intramuscular Bee Venom Herbal Acupuncture’ and ‘Intracutaneous Bee Venom Herbal Acupuncture’ in Knee Osteoarthritis Patients. J Korean Acupuncture & Moxibustion Society. 2008;28(2):151-64.
  13. Yang KR, Song HS. A Comparative study of Warm needling and Bee Venom Pharmacopuncture on Osteoarthritis of the Knee - a Randomized Controlled Trial -. J Korean Acupuncture & Moxibustion Society. 2008;11(2):21-31.
  14. Kim SC, Lim JA, Kim SN, Lee SY, Lee SK, Moon HC, et al. A Study on Pain relief effects and Allergic responses for the Osteoarthritis of the knee joint Between Sweet Bee Venom and Bee Venom Pharmacopuncture. J Korean Institute of Herbal Acupuncture. 2008;11(1):31-40.
  15. Na WM, Lee SY, Jang EH, Kim SC, Moon HC, Kim SM, et al. A Study on Pain relief effects and Allergic responses for the Osteoarthritis of the knee joint Between Sweet Bee Venom and Bee Venom Pharmacopuncture. J Korean Acupuncture & Moxibustion Society. 2007;10(2);47-55.
  16. Park KB, Song KH, Lee JS, Jo JH. Study on Clinical Effects of Homnis Placenta Herbal Acupuncture on Osteoarthritis of Knee Joint. J Korean Acupuncture & Moxibustion Society. 2006;23(4):163-73.
  17. An BJ, Kim KT, Kang MS, Song HS . Effect of Bee Venom-acupuncture on Patients with Osteoarthritis of Knee Joint. J Korean Acupuncture & Moxibustion Society. 2006;23(4):15-20.
  18. Lee SN, Hong SY, Jo HC, Byun IJ, Song HS, Kim KH. The Clinical Study on Bee Venom Acupuncture Treatment on Osteoarthritis of Knee Joint. J Korean Acupuncture & Moxibustion Society. 2003;20(5):73-81.
  19. CN Ko, IK Min, SW Park, WS Jung, SK Moon, JM Park, et al. Effectiveness of Bee Venom Acupuncture on Shoulder Pain after Stroke. J Korean Oriental Med. 2007;28(1):11-24.
  20. Eom JY, Won SH, Kwon KR, Lee HS. Comparative study of Acupuncture, Bee Venom Acupuncture and Bee Venom Herbal Acupuncture on the treatment of Post-stroke Hemiplegic Shoulder Pain. J Korean Institute of Herbal Acupuncture. 2006;9(1):139-54.
  21. Cho SW, Nam JH, Kim MS, Lee SY, Lee IS, Son DY, et al. The Effectiveness of Zingiberi Rhizoma Herbal Acupuncture Therapy and Bee Venom Herbal Acupuncture Therapy on the Poststroke Hemipegic Shoulder Pain. J Oriental Rehab Med. 2005;15(4):77-87.
  22. Bae HH, Park YC. A Effect of Jungsongouhyul Herbal Acupuncture Therapy on Quality of Life of the Poststroke Hemipegic Shoulder Pain - Randomized Controlled, Double Binding. J Korean Institute of Herbal Acupuncture. 2004;7(1):77-86.
  23. Kang I, Moon JY, Lim MJ, Cho JH, Lee HE. The Comparison Study between Different Interventions for Treating Acute Ankle Sprain - Using Dry Needle, Bee Venom Acupuncture, Hwangryunhaedoktang Herbal Acupuncture -. J Korean Acupuncture & Moxibustion Society. 2008;25(5):89-95.
  24. Soe JW, Park MJ, Sung IH, Kim NO, Ahn CK. A Clinical Study of Bee Venom Acupuncture Therapy on the Treatment of Acute Ankle Sprain. J Korean Acupuncture & Moxibustion Society. 2006;23(1):95-103.
  25. Song HS. The Effect of Bee Venom Acupuncture (BVA) on acute Ankle Sprain : A Randomized Controlled Trial and double blinding - Pilot study -. J Korean Institute of Herbal Acupuncture. 2005;8(2):11-6.
  26. Lee H. The Comparative Study on the Bee-Venom Therapy and Common Acupuncture Therapy for the Acute Ankle Sprain. Korean J Meridian & Acupoint. 2004;21(4):133-43.
  27. Kim JH, Jang SH, Yoon HM, Jang KJ, Ahn CB, Kim CH, et al. The comparison of Effectiveness between Bee Venom and Sweet Bee Venom Therapy on Chronic Lower Back Pain. J Korean Institute of Herbal Acupuncture. 2008;11(4):15-24.
  28. Lee SH, Kang MW, Lee H, Lee SY. Effectiveness of Bee-venom Acpuncture and Ouhyul Herbal Acpuncture in Herniation of Nucleus Pulposuscomparison with Acpuncture Therapy Only. J Korean Acupuncture & Moxibustion Society. 2007;24(5):197-205.
  29. Lee TH, Hwang HS, Chang SY, Cha JH, Jung KH, Lee EY, at al. The Comparison of Effectiveness between Bee Venom and Sweet Bee Venom Therapy on Low back pain with Radiating pain. J Korean Institute of Herbal Acupuncture. 2007;10(3):85-89.
  30. Kim KT, Song HS. The Effectiveness of Bee Venom Acupuncture Therapy on the Treatment of Sprain of L-spine(A Randomized Controlled Trial; Double Blinding). J Korean Institute of Herbal Acupuncture. 2005;22(4):113-20.
  31. Lee KH, Yoon HM, Song CH, Jang KJ, Ahn CB, Kim CH. Comparison of Treatment Effects and Allergic responses to stiff neck between Sweet Bee Venom and Bee Venom Pharmacopuncture. J Korean Institute of Herbal Acupuncture. 2008;11(4):39-48.
  32. Song BY. A Clinical Study on the Effects of Sweet Bee Venom Herbal Acupuncture for Patients with Whiplash Injury. J Korean Institute of Herbal Acupuncture. 2007;10(3):77-83.
  33. Kim KT, Song HS. A Randomized Controlled Double Blinding Study of Bee Venom Acupuncture Therapy on Sprain of C-spine. J Korean Acupuncture & Moxibustion Society. 2005;22 (4):189-95.
  34. Park JW, Yoon SW, Kim JS, Ryu BH. A Clinical Pilot Study of Carthami-Semen Herbal Acupuncture Treatment for Chronic Constipation. J Korean Acupuncture & Moxibustion Society. 2008;25(5):127-37.
  35. Kim SM, Jang SH, Kim CH, Youn HM, Song CH, Ahn CB, et al. Effect of Hominis placenta Pharmacopuncture on the Dysmenorrhea (A Pilot study, Single blind, Randomized, Controlled Clinical Trial. J Korean Institute of Herbal Acupuncture. 2008;11(3):123-31.
  36. Kim HK, Youn HM, Ahn CB. Clinical Studies on Hwngryunhaedok-tang Herbal Acupuncture Therapy on Functional Headache. J Korean Institute of Herbal Acupuncture. 2006;9(3): 131-8.
  37. Lim JA, Kim SC, Kim SN, Lee SY, Moon HC. Clinical study on treatment of Carpal tunnel syndrome using Scolopendrid herbal acupuncture. J Korean Institute of Herbal Acupuncture. 2005;8(1):13-20.
  38. An GH, Lee BR. The Comparative Study on the Bee Venom Therapy and Common Acupucnture Therapy for the Lateral Epicondylitis (Tennis Elbow). J A Research Institute of Oriental Med of Daejon Univ. 2004;13(2):267-76.
  39. Lee SH, Hong SJ, Kim SY, Yang HI, Lee JD, Choi DY, et al. Randomized Controlled Double Blind Study of Bee Venom Therapy on Rheumatoid Arthritis. J Korean Acupuncture & Moxibustion Society. 2003;20(3):80-8.
  40. Lim JA, Kim SN, Lee SY, Lee SK, Moon HC, Koo ST, et al. The Clinical study on the change of pain after needle acupuncture and needle acupuncture combined herbal acupuncture therapy in the musculoskeletal disorder. J Korean Institute of Herbal Acupuncture. 2005;8(2):83-90.
  41. Kwon KR. A Clinical Study on the Effects of Intravenous Wild ginsen Herbal Acupuncture on the Human Body. J Korean Institute of Herbal Acupuncture. 2006;9(3):61-77.
  42. Seol H, Yook TH. Effects of Hwangryunhaedoktang Herbal Acupuncture at G21(Kyonjong:肩井) on the Heart Rate Variability. J Korean Acupuncture & Moxibustion Society. 2004;21(6):37-50.
  43. Rho JD, Kim LH, Song BY, Yook TH. The Effects of distilled Wild Ginseng Herbal Acupuncture on the Heart Rate Variability (HRV). J Korean Institute of Herbal Acupuncture. 2008.11(1):55-69.
  44. Shin JC, Kim LH, Song BY, Yook TH. The Effects of distilled Rehmannia glutinosa Herbal Acupuncture on the Heart Rate Variability (HRV). J Korean Institute of Herbal Acupuncture. 2008;11(1):83-97.
  45. Lim ST, Kim LH, Song BY, Yook TH. The Effects of distilled Astragali Radix Herbal Acupuncture on the Heart Rate Variability (HRV). J of Oriental Neuropsychiatry. 2008;19(1):107-24.
  46. Yook TH, Ryu JS, Jung HS. Effects of Sweet Bee Venom and Bee Venom on the Heart Rate Variability. J Korean Institute of Herbal Acupuncture. 2008;11(1):41-54.
  47. Lee JS, Lee JY, Kwon KR, Lee HC. A Study on Allergic Responses btween Bee Venom and Sweet Bee Venom Pharmacopuncture. J Korean Institute of Herbal Acupuncture. 2006;9(3):61-77.
  48. Seo JC. Randomized Clinical Trials of Herbal Acupuncture for Placebo Control. J Korean Acupuncture & Moxibustion Society. 2008;25(6):153-61.
  49. Lee HY, You JS, Yook TH, Hong KE. The Effects of Distilled Astragali Radix Herbal Acupuncture, Wild Ginseng Herbal Acupuncture and Rehmannia Glutinosa Herbal Acupuncture on Vital Sign;A Randomized, Placebo-controlled, Double-blind Clinical Trial. J Korean Acupuncture & Moxibustion Society. 2007;24(5):207-17.
  50. Korean Institute of Herbal Acupuncture. Pharmacopuncturology. 1st ed. Seoul:ELSEVIER. 2008:3-5.
  51. Shin YS, Ahn YO. Methodolgy of medical research. 1st ed. Seoul:Seoul national university press. 1997:238-81.
  52. Schulz KF, Chalmers I, Hayes RJ, Altman DG. JAMA. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. 1995;273(5):408-12. https://doi.org/10.1001/jama.273.5.408
  53. Begg C, Cho M, Eastwood S, Horton R, Moher D, Olkin I, et al. Improving the quality of reporting of randomized controlled trials: the CONSORT statement. JAMA. 1996;276(8):637-9. https://doi.org/10.1001/jama.276.8.637
  54. Chalmers I. Current Controlled Trials: an opportunity to help improve the quality of clinical research. Curr Control Trials Cardiovasc Med. 2000;1(1):3-8. https://doi.org/10.1186/CVM-1-1-003
  55. Scottish Intercollegiate Guidelines Network. 2009;[1screen]. Available at:URL:http://www.sign.ac.uk/guidelines/fulltext/50/checklist2.html. Accessed June 6, 2009.
  56. MacPherson H, White A, Cummings M, Jobst KA, Rose K, Niemtzow RC, et al. Standards for reporting interventions in controlled trials of acupuncture: The STRICTA recommendations. J Altern Complement Med. 2002;8(1):85-9. https://doi.org/10.1089/107555302753507212
  57. Kim WY, Lee SD, BM Lim, Kim KS. The Assessment of Appropriateness of Acupuncture Methodology Based on STRICTA Recommendations - The Discussion of 5 Systematic Reviews and Their Objects 58 Randomized Controlled Trials Using the New Tool-. J Korean Acupuncture & Moxibustion Society. 2007;24(5):151-70.