Reproducibility Between two physicians of fMRI study on the Brain Activity Induced by Acupuncture (at BL62)

  • Yeo, S. (Meridian and Acupoint, Grad. Sch. of Basic Eastern Med. Science, Kyung Hee Univ.) ;
  • Kim, Y. (Meridian and Acupoint, Grad. Sch. of Basic Eastern Med. Science, Kyung Hee Univ.) ;
  • Choe, I.H. (Applied Meridian Med., Grad. Sch. of Applied Eastern Medicine, Kyung Hee Univ.) ;
  • Rheu, K.H. (Applied Meridian Med., Grad. Sch. of Applied Eastern Medicine, Kyung Hee Univ.) ;
  • Choi, Y.G. (Acupuncture and Meridian, WHO Collaborating Ctr. for Traditional Medicine, East-West Med. Res. Institute, Kyung Hee Univ.) ;
  • Hong, Y.M. (Meridian and Acupoint, Grad. Sch. of Basic Eastern Med. Science, Kyung Hee Univ.) ;
  • Lim, S. (Meridian and Acupoint, Grad. Sch. of Basic Eastern Med. Science, Kyung Hee Univ.)
  • Published : 2009.06.27

Abstract

목적 : 신맥 혈위 자극이 뇌활성화 변화에 미치는 영향에 있어 자침 시술자간의 재현성을 fMRI 영상을 통해 평가하고자 하였다. 방법 : 본 연구는 건강한 성인 남자 15명을 대상으로 실시하였으며, 15명의 피험자 중 7명은 각각 2회 방문하였으며, 두 시술자에 의해 침을 맞고 총 4개의 데이터를 얻었다. 나머지 8명은 1회 방문하여 두 시술자에게 침을 맞아 2개씩의 데이터를 얻어 총 44개의 fMRI 데이터를 얻었다. 실험자간의 차이를 줄이기 위해 자침의 깊이와 회전, 강도 등을 동일하게 하였으며, 우측 신맥혈에 자침하였다. 침에 의해 활성화되는 영역을 확인하기 위해 블록디자인을 사용하여 fMRI를 촬영하였다. 결과 : 다른 날에 실시한 같은 시술자내의 재현성은 24 %, 같은 날 실시한 다른 시술자간의 재현성은 64 % 로, 다른 시술자간의 재현성이 서로 다른 날 실시한 같은 시술자내의 재현성보다 높게 나타났다. 결론 : 침을 이용한 fMRI의 실험에서 시술자에 의한 차이 외에도 실험하는 날짜의 차이, 피험자 인체의 생리적인 변화 등에 의한 차이가 크다는 것을 본 실험을 통하여 확인하였다. 그리고 자침의 깊이와 회전, 자극의강도 등을 동일하게 함으로써 다른 시술자간의 재현성을 높일 수 있다는 것을 확인했다. 추후 침실험에 있어서 여러 변수들에 의한 차이를 극복하고 재현성을 높일 수 있는 방법에 관한 더욱 심도 있는 연구가 필요하다.

Keywords

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