Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
권호 표지

Hepatic Solitary Metastasis of Gastric Cancer: Radiofrequency

위암의 단일결절 간전이에 대한 고주파 열치료(Radiofrequency)

  • Received : 2009.03.09
  • Accepted : 2009.03.23
  • Published : 2009.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

The prognosis of gastric cancer with hepatic metastasis is very poor, even though several treatment modalities exist, such as surgical resection. Indeed, a standard therapy has not been established in such patients. Recently, attempts were made to treat hepatic metastasis of gastric cancer with radiofrequency (RF), which was originally used in primary or metastatic liver cancer. RF has been reported to show similar survival compared to surgical resection and is emerging as a new treatment modality even though it is still not conclusive with respect to efficacy and safety due to the paucity of reports. A prospective study is warranted to evaluate the efficacy of RF in the treatment of gastric cancer with hepatic metastasis compared with conventional modalities.

위암의 간전이는 수술적 절제, 전신적 항암약물요법, 간동 맥색전술 등의 여러 가지 치료방법이 사용되고 있으나 예후가 매우 불량하여 아직까지 표준치료방법이 정립되어 있지 않은 상황이다. 최근 간암 등에서 많이 사용되고 있는 고주파열치료(Radiofrequency)가 위암의 간전이 치료방법으로 시도되고 있으나, 아직까지 문헌에 보고된 예는 많지 않아 정확한 치료성적을 판단할 수는 없으나 기존의 수술적 방법에 비교하여 유사한 성적을 보임으로써 위암의 간전이 치료의 새로운 치료방법으로 대두되고 있다. 고주파 열치료의 치료성적을 정확히 평가하기 위하여 위암의 간전이 환자에 대한 전향적 연구가 필요한 실정이다.

Keywords

References

  1. Marrelli D, Roviello F, De Stefano A, Fotia G, Giliberto C, Garosi L, Pinto E. Risk factors for liver metastases after curative surgical procedures for gastric cancer: a prospective study of 208 patients treated with surgical resection. J Am Coll Surg 2004;198:51-58. https://doi.org/10.1016/j.jamcollsurg.2003.08.013
  2. Okano K, Maeba T, Ishimura K, Karasawa Y, Goda F, Wakabayashi H, Usuki H, Maeta H. Hepatic resection for metastatic tumors from gastric cancer. Ann Surg 2002;235:86-91. https://doi.org/10.1097/00000658-200201000-00011
  3. Sakamoto Y, Ohyama S, Yamamoto J, Yamada K, Seki M, Ohta K, Kokudo N, Yamaguchi T, Muto T, Makuuchi M. Surgical resection of liver metastases of gastric cancer: an analysis of a 17-year experience with 22 patients. Surgery 2003;133:507-511. https://doi.org/10.1067/msy.2003.147
  4. Zacherl J, Zacherl M, Scheuba C, Steininger R, Wenzl E, Muhlbacher F, Jakesz R, Langle F. Analysis of hepatic resection of metastasis originating from gastric adenocarcinoma. J Gastrointest Surg 2002;6:682-689. https://doi.org/10.1016/S1091-255X(01)00075-0
  5. Sakamoto Y, Sano T, Shimada K, Esaki M, Saka M, Fukagawa T, Katai, Kosuge T, Sasako M. Favorable indications for hepatectomy in patients with liver metastasis from gastric cancer. J Surg Oncol 2007;95:534-539. https://doi.org/10.1002/jso.20739
  6. Takahashi I, Kakeji Y, Emi Y, Sakurai M, Yonemura Y, Kimura Y, Maehara Y. S-1 in the treatment of advanced and recurrent gastric cancer: current state and future prospects. Gastric Cancer 2003;6(Suppl 1):28-33. https://doi.org/10.1007/s10120-003-0228-5
  7. Kim NK, Park YS, Heo DS, Suh C, Kim SY, Park KC, Kang YK, Shin DB, Kim HT, Kim HJ, et al. A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer. Cancer 1993;71:3813-3818. https://doi.org/10.1002/1097-0142(19930615)71:12<3813::AID-CNCR2820711205>3.0.CO;2-5
  8. Imamura H, Matsuyama Y, Shimada R, Kubota M, Nakayama A, Kobayashi A, Kitamura H, Ikegami T, Miyagawa SI, Kawasaki S. A study of factors influencing prognosis after resection of hepatic metastases from colorectal and gastric carcinoma. Am J Gastroenterol 2001;96:3178-3184. https://doi.org/10.1111/j.1572-0241.2001.05278.x
  9. Ambiru S, Miyazaki M, Ito H, Nakagawa K, Shimizu H, Yoshidome H, Shimizu Y, Nakajima N. Benefits and limits of hepatic resection for gastric metastases. Am J Surg 2001;181:279-283. https://doi.org/10.1016/S0002-9610(01)00567-0
  10. Bines SD, England G, Deziel DJ, Witt TR, Doolas A, Roseman DL. Synchronous, metachronous, and multiple hepatic resections of liver tumors originating from primary gastric tumors. Surgery 1993;114:799-805; discussion 804-805.
  11. Miyazaki M, Itoh H, Nakagawa K, Ambiru S, Shimizu H, Togawa A, Shiobara M, Ohtsuka M, Sasada K, Shimizu Y, et al. Hepatic resection of liver metastases from gastric carcinoma. Am J Gastroenterol 1997;92:490-493.
  12. Ochiai T, Sasako M, Mizuno S, Kinoshita T, Takayama T, Kosuge T, Yamazaki S, Maruyama K. Hepatic resection for metastatic tumours from gastric cancer: analysis of prognostic factors. Br J Surg 1994;81:1175-1178. https://doi.org/10.1002/bjs.1800810832
  13. Roh HR, Suh KS, Lee HJ, Yang HK, Choe KJ, Lee KU. Outcome of hepatic resection for metastatic gastric cancer. Am Surg 2005;71:95-99.
  14. D'Arsonval MA. Physiological effect of alternative currents. CR Soc Biol 1891;43:283-286.
  15. Clark WL. Oscillatory dessication in the treatment of accessible malignant growths and minor surgical conditions. J Adv Ther 1911;29:169-183.
  16. McGahan JP, Browning PD, Brock JM, Tesluk H. Hepatic ablation using radiofrequency electrocautery. Invest Radiol 1990;25:267-270. https://doi.org/10.1097/00004424-199003000-00011
  17. Rossi S, Fornari F, Pathies C, Buscarini L. Thermal lesions induced by 480 KHz localized current field in guinea pig and pig liver. Tumori 1990;76:54-57.
  18. Pereira PL. Actual role of radiofrequency ablation of liver metastses. Eur Radiol 2007;17:2062-2070. https://doi.org/10.1007/s00330-007-0587-0
  19. Mulier S, Mulier P, Ni Y, Miao Y, Dupas B, Marchal G, De Wever I, Michel L. Complications of radiofrequency coagulation of liver tumours. Br J Surg 2002;89:1206-1222. https://doi.org/10.1046/j.1365-2168.2002.02168.x
  20. McKay A, Dixon E, Taylor M. Current role of radiofrequency ablation for the treatment for colorectal liver metastases. Br J Surg 2006;93:1192-1201. https://doi.org/10.1002/bjs.5581
  21. Kosaka T, Imaizumi H, Kamei K, Usami K, Nakano Y, Ueno K, Takashima S. A case of gastric cancer patient with liver metastasis treated by radiofrequency ablation therapy combined with intra-arterial chemotherapy. Gan To Kagaku Ryoho 2004;31:1737-1739.
  22. Carditello A, Scisca C, Stilo F, Parisi A, Basile M. The possible role of radiofrequency as complementary treatment of locally advanced gastric cancer. Ann Ital Chir 2005;76:39-41.
  23. Kim YS, Rhim H, Sung JH, Kim SK, Kim Y, Koh BH, Cho OK, Kwon SJ. Bronchobiliary fistular after radiofrequency thermal ablation of hepatic tumor. J Vasc Interv Radiol 2005;16:407-410. https://doi.org/10.1097/01.RVI.0000150034.77451.6F
  24. Yamakado K, Nakatsuka A, Takaki H, Mori Y, Tonouchi H, Kusunoki M, Kida H, Takeda K. Prospective study of arterial infusion chemotherapy followed by radiofrequency ablation for the treatment of liver metastasis of gastric cancer. J Vasc Interv Radiol 2005;16:1747-1751. https://doi.org/10.1097/01.RVI.0000188738.84911.3B
  25. Cheon SH, Rha SY, Jeung HC, Im CK, Kim SH, Kim HR, Ahn JB, Roh JK, Noh SH, Chung HC. Survival benefit of combined curative resection of the stomach (D2 resection) and liver in gastric cancer patients with liver metastasis. Ann Oncol 2008;19:1146-1153. https://doi.org/10.1093/annonc/mdn026