Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Analysis and Stability test of the Extract of Coptidis Rhizoma and Salviae Miltiorrhizae Radix for Toxicity Study

황련과 단삼의 독성평가를 위한 성분분석 및 안정성 시험

  • Lee, Mi-Kyoung (College of Pharmacy, Catholic University of Daegu) ;
  • Lee, Jun-Seok (College of Pharmacy, Catholic University of Daegu) ;
  • Kwack, Seung-Jun (Department of Toxicological Research, National Institute of Toxicological Research) ;
  • Kim, Ji-Myoung (Department of Toxicological Research, National Institute of Toxicological Research) ;
  • Kang, Tae-Suk (Department of Toxicological Research, National Institute of Toxicological Research) ;
  • Lee, Je-Hyun (College of Oriental Medicine, Dongguk University) ;
  • Woo, Mi-Hee (College of Pharmacy, Catholic University of Daegu) ;
  • Choi, Jae-Sue (Faculty of Food Science and Biotechnology, Pukyoung National University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu)
  • 이미경 (대구가톨릭대학교 약학대학) ;
  • 이준석 (대구가톨릭대학교 약학대학) ;
  • 곽승준 (국립독성과학원 독성연구부) ;
  • 김지명 (국립독성과학원 독성연구부) ;
  • 강태석 (국립독성과학원 독성연구부) ;
  • 이제현 (동국대학교 한의과대학) ;
  • 우미희 (대구가톨릭대학교 약학대학) ;
  • 최재수 (부경대학교 식품생명공학부) ;
  • 배기환 (충남대학교 약학대학) ;
  • 민병선 (대구가톨릭대학교 약학대학)
  • Published : 2009.09.30
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Abstract

A simple and reliable reverse phase HPLC method of Coptidis Rhizoma and Salviae Miltiorrhizae Radix were developed to determine pharmacologically active marker compounds. The water-extract of two natural medicines were evaluated by the HPLC methods. The stability test for two extract were examined for five months. However, no significant change in the content of the marker compounds of each extract observed during the time of investigation.

Keywords

References

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