일변량 분산 분석과 이변량 시계열 분석을 이용한 미숙아의 목소리 자극에 대한 심박동수와 호흡수 반응의 비교

Comparison and Analysis of Response of Premature Infants to Auditory Stimulus

  • 발행 : 2009.07.31

초록

Purpose: The purpose of this study was to compare the result of one-way ANOVA with that of cross-correlation time series analysis in order to evaluate physiologic responses of premature infants to human voices. Methods: Four premature infants born prior to 32 weeks gestational age were included in the study. The Gould 4000TA Recording System recorded the preterm infant's heart and respiratory rate while they were listening to a pre-recorded voice recording. Each infant listened to both male and female voices (1 min each) at each testing session. Results: The results of both one-wayANOVA and cross-correlation time series analysis using heart and respiratory rate data were not consistent in some of premature infants. A cross-correlation time series analysis revealed that the responses of premature infant to vocal stimulation occurred at a varying number of seconds after the stimulus was presented and lasted for over 20-30 sec. Conclusion: The results indicate that a time series analysis can provide more detailed information on the rapidly changing physiologic status of premature infant to the auditory stimulus. In addition, the results provide an insight into an auditory responsitivity of premature infants to a naturally occurring sound, the human voice, in the neonatal intensive care unit.

키워드

참고문헌

  1. Arnon, S., Shapsa, A., Forman, L., Regev, R., Bauer, S., Litmanovitz, I., & Dolfin, T. (2006). Live music is beneficial to preterm infants in the neonatal intensive care unit environment. Birth, 33, 131-136. https://doi.org/10.1111/j.0730-7659.2006.00090.x
  2. Bae, J. W. (2002). Changes of incidence and mortality of prematurity and low birth weight infants in Korea. Medical Postgraduates, 4, 169-174.
  3. Barreto, E. D., Morris, B. H., Philbin, M. K., Gray, L. C., & Lasky, R. E. (2006). Do former preterm infants remember and respond to neonatal intensive care unit noise? Early Human Development, 82, 703-707. https://doi.org/10.1016/j.earlhumdev.2006.02.009
  4. Birnholz, J. C., & Benacerraf, B. R. (1983). The development of human fetal hearing. Science, 222, 516-518. https://doi.org/10.1126/science.6623091
  5. Bozzette, M. (1997). Premature infant responses to taped maternal voice. Unpublished dissertation, University of Washington, Seattle, USA.
  6. Bremmer, P., Byers, J. F., & Kiehl, E. (2003). Noise and the premature infant: Physiological effects and practice implications. Journal of Obstetric Gynecologic Neonatal Nursing, 32, 447-454. https://doi.org/10.1177/0884217503255009
  7. Clarkson, M. G., & Berg, W. K. (1983). Cardiac orienting and vowel discrimination in newborns, crucial stimulus parameters. Child Development, 54, 162-171. https://doi.org/10.2307/1129873
  8. Committee on Environmental Health(. 1997). Noise: A hazard for the fetus and newborn. Pediatrics, 100, 724-727. https://doi.org/10.1542/peds.100.4.724
  9. Cuevas, K. D., Silver, D. R., Brooten, D., Youngblut, J. M., & Bobo, C. M. (2005). The cost of prematurity: Hospital charges at birth and frequency of rehospitalizations and acute care visits over the first year of life. American Journal of Nursing, 105(7), 56-64. https://doi.org/10.1097/00000446-200507000-00031
  10. Fifer, W. P., & Moon, C. M. (1994). The role of mother's voice in the organization of brain function in the newborn. Acta Peadiatric Supplement, 397, 86-94.
  11. Fox, N. A., & Lewis, M. (1983). Cardiac response to speech sounds in preterm infants: effects of postnatal illness at three months. Psychophysiology, 20(5), 28-37.
  12. Gerhardt, K. J., & Abrams, R. M. (2000) Fetal exposures to sound and vibroacoustic stimulation. Journal of Perinatology, 20(8), S21- S30. https://doi.org/10.1038/sj.jp.7200446
  13. Gray, L., & hilbPin, M. K. (2004). Effects of the neonatal intensive care unit on auditory attention and distraction. Clinics in Perinatology, 31, 243-260. https://doi.org/10.1016/j.clp.2004.04.013
  14. Hall, J. W. (2000). Development of the ear and hearing. Journal of Perinatology, 20(8), S12-S20. https://doi.org/10.1038/sj.jp.7200439
  15. Hepper, P. G., & Shahidullah, B. S. (1994). Development of fetal hearing. Archives in Disease of Children, 71, F81-F87. https://doi.org/10.1136/fn.71.2.F81
  16. Hunt, C. E. (2006). Ontogeny of autonomic regulation in late preterm infants born at 34-37 weeks postmenstrual age. Seminar in Perinatology, 30, 73-76.
  17. Kim, S. S., Kim, M. H., Shin, J. W., Young, S. Y., Lee, E. K., Chang, Y. S., et al. (2002). Changes in the outcomes of very low birth weight infants. Journal of Korean Pediatric Society, 45, 828-835.
  18. Korea National Statistical Office. (2007). Birth statistics.
  19. Longin, E., Gerstner, T., Schaible, T., Lenz, T., & Konig, S. (2006). Maturation of the autonomic nervous system: Differences in heart rate variability in premature vs. term infants. Journal of Perinatal Medicine, 34, 303-308. https://doi.org/10.1515/JPM.2006.058
  20. Martine, J., Hamilton, B., Sutton, P., Ventura, S., Menacker, F., & Krimeyer, S. (2007). Births: Final data for 2005. National Vital Statistics Reports, 53, 1-17.
  21. Patel, M., Nelson, M. N., White-Truat, R., & Meleedy-Rey, P. (2004). Use of the Box-Jenkins method to evaluate the physiologic responses of normal and CNS-injured premature infants to environmental sound. Newborn Infant Nursing Review, 4, 162-169. https://doi.org/10.1053/j.nainr.2004.03.004
  22. Robertson, A., Cooper-Peel, C., & Vos, P. (1998). Peak noise distribution in the neonatal intensive care nursery. Journal of Perinatology, 18, 361-364.
  23. Volpe, J. J. (2001). Neurobiology of periventricular leukomalacia in the premature infant. Pediatric Research, 50, 553-562. https://doi.org/10.1203/00006450-200111000-00003
  24. Wharrd, H. J., & Davis, A. C. (1997). Behavioral and autonomic responses to sound in pre-term and full-term babies. British Journal of Audiology, 31, 3315-3329.
  25. White-Tarut, R., Nelson, M. N., Burns, K., & Cunningham, N. (1994). Environmental influences on the developing premature infant: Theoretical issues and applications to practice. Journal of Obstetric Gynecologic Neonatal Nursing, 23, 393-401. https://doi.org/10.1111/j.1552-6909.1994.tb01896.x
  26. White-Traut, R., Nelson, M. N., Silvestri, J. M., Cunnigham, N., & Patel, M. (1997). Responses of preterm infants to unimodal and multimdoal sensory intervention. Pediatric Nursing, 23, 169- 175.
  27. Zahr, L. K., & Balian, S. (1995). Response of premature infants to routine nursing interventions and noise in the NICU. Nursing Research, 44, 179-185.
  28. Zimmer, E. Z., Fifer, W. P., Kim, Y., Rey, H. R., Chao, C. R., & Myers, M. M. (1993). Response of the premature fetus to stimulation by speech sounds. Early Human Development, 33, 207- 215. https://doi.org/10.1016/0378-3782(93)90147-M