혜화의학회지 (Journal of Haehwa Medicine)

  • 제18권1호
  • /
  • Pages.1-8
  • /
  • 2009
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  • 2586-3002(pISSN)
  • /
  • 2586-3347(eISSN)
대전대학교 한의학연구소 (Research Institute of Korean Medicine)
권호 표지

보완대체의학의 천식 흡입치료제 연구 동향

Research trends of inhalation drug for asthma in complementary and alternative medicine

  • 양수영 (대전대학교 한의과대학 폐계내과학교실) ;
  • 오지석 (대전대학교 한의과대학 폐계내과학교실) ;
  • 박양춘 (대전대학교 한의과대학 폐계내과학교실) ;
  • 오영선 (대전대학교 혜화병원 내과) ;
  • 이용구 (대전대학교 혜화병원 내과)
  • Yang, Su-Young (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine Daejeon University) ;
  • Oh, Ji-Seok (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine Daejeon University) ;
  • Park, Yang-Chun (Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine Daejeon University) ;
  • Oh, Young-Seon (Internal Medicine, Hye Hwa Hostpital, Daejeon University) ;
  • Lee, Yong-Koo (Internal Medicine, Hye Hwa Hostpital, Daejeon University)
  • 발행 : 2009.06.30
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초록

This study analyzed the contents of the research papers of Complementary Medicine concerning the inhalation drug for asthma published in Pubmed during lately 10 years. As a result, the following conclusion was drawn. 1. There were 5 papers concerning 2 review articles, 2 experimental studies and 1 clinical study. 2. Interventions of research papers are glutathione, microorganism fermentation extract (EM-X), ginkgolide and compound Chinese herbal monomer recipe (ligustrazin, baicalin, ginkgolide). 3. There is no controlled study for effect of inhaled glutathione, on the contrary it induced bronchial constriction in sulfites sensitive asthmatics. 4. Inhalation of EM-X reduced airway hyper-reactivity and level of IL-4, IL-5 and IL-13 in OVA challenged asthmatic mice. 5. Ginkgolide nebulized inhalation reduced symptomatic scorings and eosinophil cationic protein, improved FEV1 and PEF. 6. Compound Chinese herbal monomer (CHM) recipe reduced blood eosinophil count, eosinophil count and total cell cound in BALF, depressed airway hyper-responsiveness and airway inflammation.

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