핵의학기술 (The Korean Journal of Nuclear Medicine Technology)
- 제13권1호
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- Pages.98-103
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- 2009
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- 1229-9901(pISSN)
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- 2982-8406(eISSN)
Cr-51 EDTA GFR 검사 결과의 분석 및 의의
Estimation of Glomerular Filtration Rate using Chromium-51 EDTA
- Lim, Soo-Yeon (Department of Nuclear Medicine, Asan Medical Center) ;
- Moon, Hyoung-Ho (Department of Nuclear Medicine, Asan Medical Center) ;
- Yoo, Seon-Hee (Department of Nuclear Medicine, Asan Medical Center) ;
- Cho, Shee-Man (Department of Nuclear Medicine, Asan Medical Center)
- 투고 : 2009.01.07
- 심사 : 2009.02.05
- 발행 : 2009.05.11
초록
Purpose: Correct estimation of Glomerular filtration rate (GFR) is very important for an accurate clinical assessment of the kidney function. This study compares four GFR markers, a serum creatinine-based estimation using MDRD formula, Cystatin-C, Cr-51 EDTA 2 samples and 6 samples. Materials and Methods: Serum creatinine concentrations, Cystatin-C serum concentrations and Cr-51 EDTA clearance are measured in 43 patients who received or donated kidney. Results: The correlation coefficient between serum based estimated GFR (MDRD) and Cr-51 EDTA 6 samples was 0.817 (p<0.01). The correlation coefficient between Cystatin-C based GFR and EDTA 6 samples was 0.7322 (p<0.01). Regression analysis showed a statistically significant correlation between Cr-51 EDTA 2 samples and 6 samples (r=0.971, p<0.01). Mean value and