Effect of Extended Field of View on Measurements of Standardized Uptake Value in PET/CT

PET/CT검사에서 CT의 확대 유효시야 적용이 표준화섭취계수에 미치는 영향

  • Park, Soon-Ki (Department of Nuclear Medicine, Asan Medical Center) ;
  • Nam, Ki-Pyo (Department of Nuclear Medicine, Asan Medical Center) ;
  • Kim, Kyeong-Sik (Department of Nuclear Medicine, Asan Medical Center) ;
  • Shin, Sang-Ki (Department of Nuclear Medicine, Asan Medical Center)
  • 박순기 (서울아산병원 핵의학과) ;
  • 남기표 (서울아산병원 핵의학과) ;
  • 김경식 (서울아산병원 핵의학과) ;
  • 신상기 (서울아산병원 핵의학과)
  • Received : 2008.12.03
  • Accepted : 2009.01.02
  • Published : 2009.05.11

Abstract

Purpose: The purpose of this study was to evaluate the effect of extended CT field of view (FOV) on PET/CT of Standardized uptake value (SUV) when imaging extends beyond the CT FOV. Materials and Methods: CT images were reconstructed at different FOV sizes (500 and 700 mm). Two sets of CT images were reconstructed from the CT projection data by using two FOV sizes. Twenty patients were used in this study. PET images were reconstructed using attenuation maps with 500 mm CT FOV and 700 mm extended CT FOV images. Region of interests (ROIs) drawn on the PET images. In addition, twenty patients' PET images reconstructed by 500 mm CT FOV and 700 mm extended CT FOV were compared with $SUV_{max}$. Results: When using attenuation maps with 700 mm extended CT FOV, the $SUV_{max}$ analysis of liver (p=0.000), lung (p=0.007), mediastinum (p=0.001) were statistically significant. Conclusions: 700 mm extended CT FOV helps to recover the true activity distribution in the PET emission data. In addition, 700 mm extended CT FOV has affected SUV measurement of liver, lung, mediastinum.

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