핵의학기술 (The Korean Journal of Nuclear Medicine Technology)
- 제13권3호
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- Pages.152-155
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- 2009
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- 1229-9901(pISSN)
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- 2982-8406(eISSN)
갑상선암에서의 혈중 Thyroglobulin 농도와 침생검 검체 Washout Solution의 Thyroglobulin 농도와의 상관관계
Correlation of Serum Thyroglobulin and Thyroglobulin in the Wash out of the Needle in Thyroid Cancer
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An, Jae-Seok
(Department of Nuclear Medicine, Research Institute & Hospital, National Cancer Center) ;
- Kim, Ji-Na (Department of Nuclear Medicine, Research Institute & Hospital, National Cancer Center) ;
- Won, Woo-Jae (Department of Nuclear Medicine, Research Institute & Hospital, National Cancer Center)
- 투고 : 2009.08.07
- 심사 : 2009.09.06
- 발행 : 2009.10.10
초록
목적: 혈중 thyroglobulin 농도 측정(혈중 TG)은 갑상선암 수술 후 재발 및 전이여부를 판단하는데 중요한 지표이다. 최근엔 혈중 TG와 함께 침생검 검체의 washout solution을 이용한 TG 농도 측정(washout TG)이 추적 검사에 빈번히 사용되고 있다. 본 연구는 혈중 TG와 washout TG간에 어떠한 연관성이 있는지 알아보고자 한다. 대상 및 방법: 2007년 1월부터 2008년 2월까지 국립암센터에 내원한 갑상선암 환자 중 washout TG 와 혈중 TG를 함께 측정한 47명 중 혈중 Anti-Tg Ab 양성(
Purpose: The most widely accepted tool for follow up management of thyroid cancer patients is serum thyroglobulin (Tg) measurement, but its value is limited by the interference of anti-thyroglobulin antibodies (anti-Tg Ab). Recently thyroglobulin measurement in the wash out of fine-needle aspiration biopsy specimens (Tg-FNAB) is frequently used for differential diagnosis of recurrences/metastases. The aim of this study was the investigation of the diagnostic utility of Tg-FNAB compared with serum Tg. Materials and Methods: We enrolled 41 consecutive patients with thyroid cancer who were evaluated for Tg-FNAB between January 2007 and February 2008 retrospectively. We ruled out 6 patients who anti-Tg Ab positive (