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Effect of Dietary Zinc Levels on Calcium, Magnesium, Sodium, and Potassium Contents in Rats

아연의 섭취 수준이 흰쥐의 칼슘, 마그네슘, 나트륨, 칼륨 함량에 미치는 영향

  • Kim, Hyun-Sook (Dept. of Food and Nutrition, Sookmyung Women's University) ;
  • Kang, Mun-Hui (Dept. of Food and Nutrition, Sookmyung Women's University) ;
  • Sung, Chung-Ja (Dept. of Food and Nutrition, Sookmyung Women's University)
  • 김현숙 (숙명여자대학교 식품영양학과) ;
  • 강문희 (숙명여자대학교 식품영양학과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • Published : 2009.08.31

Abstract

The effect of dietary zinc levels on macro mineral contents was investigated in rats. Rats were divided into three groups by zinc levels, such as low (50% of requirement, Zn/L), adequate (100%, Zn/A) and high (200%, Zn/H) levels of dietary zinc. The calcium, magnesium, sodium and potassium contents in serum and organs were measured. The food intake was significantly higher in Zn/L group compared to that of Zn/H group. The body weight gain in Zn/H group was significantly lower than that of other two groups. There were no significant differences in liver, kidney and spleen weights. Also, serum calcium, magnesium, sodium and potassium concentrations were not significantly changed by the zinc diet at any level. In the low zinc diet group, liver calcium content was significantly lower, but the magnesium and potassium contents in spleen were significantly higher than that in other groups. The calcium, magnesium, sodium and potassium contents of kidney were not significantly different for any level of zinc. In conclusion, the macro mineral contents of liver and spleen in the normal rats were changed by zinc levels. Based on this study, the interaction between micro and macro minerals remains to be further studied.

아연의 공급수준이 다량 무기질 함량에 미치는 영향을 알아보기 위해 흰쥐를 대상으로 아연을 결핍, 적정, 과잉 수준으로 공급하여 혈청 및 조직의 칼슘, 마그네슘, 나트륨, 칼륨함량을 분석하였다. 아연 공급수준을 달리했을 때 혈청의 다량 무기질 함량은 유의적인 차이를 보이지 않았지만 간과 비장에 영향을 주는 것으로 나타났다. 특히 아연의 결핍은 간의 칼슘 함량을 감소시키는 영향을 주었고, 아연의 과잉은 비장 마그네슘과 칼륨 함량을 감소시키는 결과를 나타냈다. 결론적으로 아연의 결핍과 과잉이 간과 비장의 다량 무기질함량에 영향을 주는 것으로 나타났는데, 특히 아연의 결핍이 더 많은 조직 내 무기질 함량 변화를 가져왔다. 그러나 본 연구에서는 아연의 결핍수준을 적정수준의 50%, 그리고 과잉을 200%로 설정하였으나 앞으로 좀 더 세분화된 아연의 결핍과 과잉 수준에 대한 체계적인 연구가 필요하다고 사료 된다.

Keywords

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