참고문헌
- Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J Cell Biol. 1998;140: 911-23 https://doi.org/10.1083/jcb.140.4.911
- Blitzblau R, Gupta S, Djali S, Robinson MB, Rosenberg PA. The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures. Eur J Neurosci. 1996;8:1840-52 https://doi.org/10.1111/j.1460-9568.1996.tb01328.x
- Choi DW. Excitotoxic cell death. J Neurobiology. 1992;23:1261-76 https://doi.org/10.1002/neu.480230915
- Chow HC, Lynch III JJ, Rose K, Choi DW. Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA. Brain Res. 1994;639:102-8 https://doi.org/10.1016/0006-8993(94)91769-8
- Ekert PG, Silke J, Vaux DL. Caspase inhibitors. Cell Death Differentiation. 1999;6:1081-6 https://doi.org/10.1038/sj.cdd.4400594
- Estevez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS. Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. J Neurosci. 1998;18:923-31
- Griffiths R, Dunlop J, Gorman A, Senior J, Grieve A. L-transpyrrolidine-2,4- dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994;47:267-74 https://doi.org/10.1016/0006-2952(94)90016-7
- Harris ME, Wang Y, Pedigo NJ, Hensley K, Butter.eld DA, Carney JM. Amyloid beta peptide (25-35) inhibits Nadependent glutamate uptake in rat hippocampal astrocyte cultures. J Neurochem. 1996;67:277-86 https://doi.org/10.1046/j.1471-4159.1996.67010277.x
- Himi T, Ikeda M, Yasuhara T, Murota SI. Oxidative neuronal death caused by glutamate uptake inhibition in cultured hippocampal neurons. J Neurosci Res. 2003;71:679-88 https://doi.org/10.1002/jnr.10510
- Huang PP, Esquenazi S, Le Roux PD. Cerebral cortical neuron apoptosis after mild excitotoxic injury in vitro: different roles of mesencephalic and cortical astrocytes. Neurosurgery. 1999;45:1413-22 https://doi.org/10.1097/00006123-199912000-00029
- Lin CL, Bristol LA, Jin L, Dykes HM, Crawford T, Clawson L, Rothstein JD. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron. 1998;20:589-602 https://doi.org/10.1016/S0896-6273(00)80997-6
- Lievens J-C, Dutertre M, Forni C, Salin P, Goff LK-L. Continuous administration of the glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate produces striatal lesion. Brain Res Mol Brain Res. 1997;50:181-9 https://doi.org/10.1016/S0169-328X(97)00182-4
- Massieu L, Moralesvillagran A, Tapia R. Accumulation of extracellular glutamate by inhibition of its uptake is not sufficient for inducing neuronal damage: an in vivo microdialysis study. J Neurochem. 1995;64:2262-72 https://doi.org/10.1046/j.1471-4159.1995.64052262.x
- Montiel T, Camacho A, Estrada-Sánchez AM, Massieu L. Differential effects of the substrate inhibitor l-transpyrrolidine-2,4-dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta-benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat brain in vivo. Neuroscience. 2005;133:667-78 https://doi.org/10.1016/j.neuroscience.2004.11.020
- Nakagawa T, Otsubo Y, Yatani Y, Shirakawa H, Kaneko S. Mechanisms of substrate transport-induced clustering of a glial glutamate transporter GLT-1 in astroglial-neuronal cultures. Eur J Neurosci. 2008;28:1719-30 https://doi.org/10.1111/j.1460-9568.2008.06494.x
- Nicholls D, Attwell D. The release and uptake of excitatory amino acids. Trends Pharmacol Sci. 1990;11:462-8 https://doi.org/10.1016/0165-6147(90)90129-V
- Padmanabhan J, Park DS, Greene LA, Shelanski ML. Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis. J Neurosci. 1999;19: 8747-56
- Robinson MB, Djali S, Buchhalter JR. Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4- dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures. J Neurochem. 1993;61:2099-103 https://doi.org/10.1111/j.1471-4159.1993.tb07447.x
- Rossi DJ, Oshima T, Attwell D. Glutamate release in severe brain ischemia is mainly by reversed uptake. Nature. 2000;403:316-21 https://doi.org/10.1038/35002090
- Schousboe A, Sonnewald U, Civenni G, Gegelashvili G. Role of astrocytes in glutamate homeostasis. Implications for excitotoxicity. Adv Exp Med Biol. 1997;429:195-206
- Son Y, Chun SW. Effects of hydrogen peroxide on neuronal excitability and synaptic transmission in rat substantia gelatinosa neurons. Int J Oral Biol. 2007;32:153-160
- Springer JE, Azbill RD, Mark RJ, Begley JG, Waeg G, Mattson MP. 4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake. J Neurochem. 1997;68:2469-76 https://doi.org/10.1046/j.1471-4159.1997.68062469.x
- Tan S, Wood M, Maher P. Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J Neurochem. 1998;71:95-105 https://doi.org/10.1046/j.1471-4159.1998.71010095.x
- Thornberry NA. Caspases: a decade of death research. Cell Death Differentiation. 1999;6:1023-7 https://doi.org/10.1038/sj.cdd.4400607
- Velasco I, Tapia R, Massieu L. Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures. J Neurosci Res. 1996;44:551-61 https://doi.org/10.1002/(SICI)1097-4547(19960615)44:6<551::AID-JNR5>3.0.CO;2-A
- Volterra A, Bezzi P, Rizzini BL, Trotti D, Ullensvang K, Danbolt NC, Racagni G. The competitive transporter Ltrans-pyrrolidine-2,4-dicarboxylate triggers excitotoxicity in rat cortical neuron-astrocyte co-cultures via glutamate release rather than uptake inhibition. Eur J Neurosci. 1996;8:2019-28 https://doi.org/10.1111/j.1460-9568.1996.tb01345.x
- Wang GJ, Chung HJ, Schnuer J, Pratt K, Zable AC, Kavanaugh MP, Rosenberg PA. High affinity glutamate transport in rat cortical neurons in culture. Mol Pharmacol. 1998;53:88-96 https://doi.org/10.1124/mol.53.1.88