A Case of Nasopharyngeal Carcinoma with Metastatic Axillary Node after Concurrent Chemoradiotherapy

치료 후 액와 림프절의 전이를 보인 비인강암 1례

  • Hong, Hyun-Jun (Department of Otorhinolaryngology, National Health Insurance Corporation Ilsan Hospital) ;
  • Lee, Won-Il (Department of Otorhinolaryngology, National Health Insurance Corporation Ilsan Hospital) ;
  • Park, Mi-Na (Department of Otorhinolaryngology, National Health Insurance Corporation Ilsan Hospital) ;
  • Chung, Eun-Ji (Department of Radiation Oncology, National Health Insurance Corporation Ilsan Hospital) ;
  • Kim, Yong-Tai (Internal Medicine, National Health Insurance Corporation Ilsan Hospital) ;
  • Choi, Eun-Chang (Department of Otorhinolaryngology, Yonsei University College of Medicine)
  • 홍현준 (국민건강보험공단 일산병원 이비인후과) ;
  • 이원일 (국민건강보험공단 일산병원 이비인후과) ;
  • 박미나 (국민건강보험공단 일산병원 이비인후과) ;
  • 정은지 (국민건강보험공단 일산병원 방사선종양학과) ;
  • 김용태 (국민건강보험공단 일산병원 혈액종양내과) ;
  • 최은창 (연세대학교 의과대학 이비인후과학교실)
  • Published : 2009.05.22

Abstract

Nasopharyngeal carcinomas are epithelial neoplasm derived from nasopharyngeal mucosa. Nasopharyngeal carcinoma involved cervical lymph nodes frequently. However, nasopharyngeal carcinoma with metastatic axillary node after concurrent chemoradiotherapy was reported rarely. We report the patients who was a 34-year-old man diagnosed as nasopharyngeal carcinoma. He was treated by concurrent chemo-radiotherapy. But axillary node metastasis was found after treatment in 2 years. After surgical resection of axillary lymph node, there is no evidence of disease.

Keywords

References

  1. Ho JH. An epidemiologic and clinical study of nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 1978;4(3-4):182-198 https://doi.org/10.1016/0360-3016(78)90137-2
  2. Dubrulle F, Souillard R, Hermans R. Extension patterns of nasopharyngeal carcinoma. Eur Radiol. 2007;17:2622-2630 https://doi.org/10.1007/s00330-007-0616-z
  3. Farias TP, Dias FL, Lima RA, Kliqerman J, de Sa GM, Barbosa MM, et al. Prognostic factors and outcome for nasopharyngeal carcinoma. Arch Otolaryngol Head Neck Surg. 2003;129(7): 794-799 https://doi.org/10.1001/archotol.129.7.794
  4. Dickson RI. Nasopharyngeal carcinoma: an evaluation of 209 patients. Laryngoscope. 1981;91(3):333-354 https://doi.org/10.1288/00005537-198103000-00001
  5. Zhu XN, Chen R, Kong FH, Liu W. Human Leukocyte antigens-A,-B,-C and -DR and nasopharyngeal carcinoma in northern China. Ann Otol Rhinol Laryngol. 1990;99:286-287 https://doi.org/10.1177/000348949009900407
  6. Yuan JM, Wang XL, Xiang YB, Gao YT, Ross RK, Yu MC. Preserved foods in relation to risk of nasopharyngeal carcinoma in Shanghai, China. Int J Cancer. 2000;85(3):358-363 https://doi.org/10.1002/(SICI)1097-0215(20000201)85:3<358::AID-IJC11>3.0.CO;2-E
  7. Skinner DW, Van Hasselt CA, Tsao SY. Nasopharyngeal carinoma: Modes of presentation. Ann Otol Rhinol Laryngol. 1991;100(7):544-551 https://doi.org/10.1177/000348949110000705
  8. Baek SJ, Lee SY, Lim YC, Koo BS, Lee JS, Lee CG, et al. Treatment Outcome, Prognostic Factors and Patterns of Failure of nasopharyngeal carcinoma. Korean J Otolaryngol. 2005;48:1254-1260
  9. Vikram B, Strong EW, Manolatos S, Mishra UB. Improved survival in carcinoma of the nasopharynx. Head Neck Surg. 1984;7(2):123-128 https://doi.org/10.1002/hed.2890070206
  10. Wei WI. Contribution of the Otorhinolaryngologist to the Management of Nasopharyngeal Carcinoma. Korean J Otolaryngol.2002;45:311-317
  11. Nakamura T, Kodaira T, Tachibana H, Tomita N, Tomoda T, Nakahara R, et al. Chemoradiotherapy for locally recurrent nasopharyngeal carcinoma: Treatment outcome and prognostic factors. Japanease J Clin Oncol. 2008;38(12):803-9. Epub 2008 Oct 7 https://doi.org/10.1093/jjco/hyn104
  12. Lee CM, Hayostek CJ, Abbott TM, Hathaway PB, Watson GA. Nasopharyngeal carcinoma with axillary node involvement as a component of failure following chemoradiotherapy. Ear Nose Throat J. 2005;84(3):159-160