대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
권호 표지

양간화담탕(凉肝化痰湯)이 고혈압에 마치는 영향

The Effect of Yangganhwadam-tang(YHT) on Hypertension

  • 오용성 (대전대학교 한의과대학 심계내과학교실) ;
  • 안정조 (대전대학교 한의과대학 심계내과학교실) ;
  • 조현경 (대전대학교 한의과대학 심계내과학교실) ;
  • 유호룡 (대전대학교 한의과대학 심계내과학교실) ;
  • 설인찬 (대전대학교 한의과대학 심계내과학교실) ;
  • 김윤식 (대전대학교 한의과대학 심계내과학교실)
  • Oh, Yong-Sung (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University) ;
  • An, Joung-Jo (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University) ;
  • Jo, Hyun-Kyung (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University) ;
  • Yoo, Ho-Rhyong (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University) ;
  • Seol, In-Chan (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University) ;
  • Kim, Yoon-Sik (Dept. of Internal Medicine College of Oriental Medicine, Dae-Jeon University)
  • 발행 : 2009.12.30
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초록

This experiment was performed to determine the antihypertensive effect of Yangganhwadam-tang(YHT) on hypertension in spontaneously hypertensive rat. The results obtained were as follows : 1. YHT showed scavenging activity on DPPH free radical and SOD-like activity. 2. YHT significantly decreased heart weight. 3. YHT significantly decreased blood pressure and pulse. 4. YHT significantly decreased the level of plasma aldosterone. 5. YHT significantly decreased the level of norepinephrine. 6. YHT significantly decreased the levels of potassium and calcium. 7. YHT significantly decreased the level of BUN. 8. YHT decreased eosinophilic changes in the heart cells, and dilated renal arterioles stenosis. These results suggest that YHT might be effective in treatment and prevention of hypertension.

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