The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
권호 표지

Effects of Eriobotryae Folium as Anti-Oxidant on HaCaT keratinocyte

비파엽(枇杷葉) 에탄올 추출물이 인간 유래 정상 피부 세포에 미치는 항산화 효과

  • 박윤희 (동신대학교 한의과대학 안이비인후과학교실) ;
  • 김종환 (동신대학교 한의과대학 안이비인후과학교실) ;
  • 최정화 (동신대학교 한의과대학 안이비인후과학교실) ;
  • 박수연 (동신대학교 한의과대학 안이비인후과학교실)
  • Received : 2009.10.11
  • Accepted : 2009.11.30
  • Published : 2009.12.25
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Abstract

Objective : The present study designed this study to investigate anti-oxidative effects of EF on HaCaT keratinocyte. Method : The present study measured the amount of polyphenoics and flavonoids, and also measured the levels of catalase, Ascorbate peroxidase (APX), SOD like activities and DPPH free radical scavenging activity. Then the effects of SB on viability and prolferation rates, and protective effects against oxidative stress induced by chemicals such as hydrogen peroxide and rotenone were also investigated. Results and conclusion : EF showed protective effect against cell death of HaCaT keratinocyte induced by rotenone and SNP significantly. In conclusion, these results suggest that EF may have anti-oxidantic action in human skin and also suggest that EF can be used as anti-aging agent.

Keywords

References

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