참고문헌
- Alslev B, B Korsgaard and P Bjerregaard. 2005. Estrogenicity of butylparaben in rainbow trout Oncorhynchus mykiss exposed via food and water. Aquat. Toxicol. 72:295-304 https://doi.org/10.1016/j.aquatox.2005.01.005
-
Andersen HR, AM Andersson, SF Arnold, H Autrup, M Barfoed, NA Beresford, P Bjerregaard, LB Christiansen, B Gissel, R Hummel, EB J
${\o}$ rgensen, B Korsgaard, R Le Guevel, H Leffers, J McLachlan, A M${\o}$ ller, JB Nielsen, N Olea, A Oles-Karasko, F Pakdel, KL Pedersen, P Perez, NE Skakkeboek, C Sonnenschein and AM Soto, JP Sumpter, SM Thorpe and P Grardjean. 1999. Comparison of short-term estrogenicity tests for identification of hormone-sisrupting chemicals. Environ. Health Perspect. 107(Suppl. 1):89-108 - Applied Research Laboratories. 1939. Special Research Report
- Bairati GG, A Lombardo and G Tettamanti. 1994. The esters of p-hydroxy-benzoate (parabens) inhibit the release of lysosomal enzymes by mitogen-stimulated peripheral human lymphocytes in culture. Chlinica. Chimica. Acta. 224:147-157 https://doi.org/10.1016/0009-8981(94)90181-3
- Batts AH, C Marriott, GP Martin, CF Wood and SW Bond. 1990. The effect of some preservations used in nasal preparations on the mucus and ciliary components of mucociliary clearance. J. Pharm. Pharmacol. 42:145-151 https://doi.org/10.1111/j.2042-7158.1990.tb05374.x
- Beral V. 2003. Breast cancer and hormone replacement in the million women study. Lancet. 362:419-27 https://doi.org/10.1016/S0140-6736(03)14065-2
- Bjerregaard P, DN Anderson, KL Pedersen, KL Pedersen and B Korsgaard. 2003. Estrogenic effect of propylparaben (propylhydroxybenzoate) in rainbow trout Oncorhynchus mykiss after exposure via food and water. Comp. Biochem. Physiol. C 136:309-317 https://doi.org/10.1016/j.cca.2003.10.004
- Blair RM, H Fang, WS Branham, BS Hass, SL Dial, CL Moland, W Tong, L Shi, R Perkins and DM Sheehan. 2000. The estrogen receptor binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol. Sci. 534:138-153
- CTFA. 1980c. Acute oral, dermal and mucus membrane toxicity testing of product containing butyl paraben and propyl paraben. CTFA Code No. 2-7-52
- Darbre PD, A Aljarrah, WR Miller, NG Coldham, MJ Sauer and GS Pope. 2004. Concentrations of parabens in human breast tumours. J. Appl. Toxicol. 24:5-13 https://doi.org/10.1002/jat.958
- Darbre PD, JR Byford, LE Shaw, RA Horton, GS Pope and MJ Sauer. 2002. Oestrogenic activity of isobutylparaben in vitro and in vivo. J. Appl. Toxicol. 22:219-226 https://doi.org/10.1002/jat.860
- Darbre PD, JR Byford, LE Shaw, S Hall, NG Coldham, GS Pope and MJ Sauer. 2003. Oestrogenic activity of benzylparaben. J. Appl. Toxicol. 23:43-51 https://doi.org/10.1002/jat.886
- Darbre PD and PW Harvey. 2008. Paraben esters: review of recent studies of endocrine toxicity, absorption, esterase and human exposure, and discussion of potential human health risks. J. Appl. Toxicol. 28:561-567 https://doi.org/10.1002/jat.1358
- Daston GP. 2004. Developmental toxicity evalultion of butylparaben in Sprague-Dawley rats. Birth Defects Res., Part B, Dev. Reprod. Toxicol. 71:296-302 https://doi.org/10.1002/bdrb.20016
- Dhooge W, N van Larebeke, G Koppen, V Nelen, G Schoeters and R Vlietinck. 2006. Serum dioxin-like activity is associated with reproductive parameters in young men from the general Flemish population. Environ. Health Perspect. 114:1670-1676
- Elder RL. 1984. The cosmetic ingredient review-a safety evaluation program. J. Am. Acad. Dermatol. 11:1168-1174 https://doi.org/10.1016/S0190-9622(84)80205-4
- FDRL. 1972. Teratologic evaluation of FDA 71-38 (methyl paraben) U.S. NTIS report (PB-221 785), pp42
- Fisher JS, KJ Turner, D Brown and RM Sharpe. 1999. Effect of neonatal exposure to estrogenic compounds on deelopment of the excurrent ducts of the rat testis through puberty to adulthood. Environ. Health Persp. 107:397-405 https://doi.org/10.1289/ehp.99107397
- Fitak B and S Krauz. 1969. Effect of preservative agents on the content of nucleic acids and proteins in animal cells in tissue culture. II. Effect of preservative agents on animal cells. Rocz. Panstw. Zakl. Hig. 20:698-710
- Frederiksen H, C Taxvig, U Hass, AM Vinggaard and C Nellemann. 2008. Higher levels of ethyl paraben and butyl paraben in rat amniotic fluid than in maternal plasma after subcutaneous administration. Toxicol. Sci. 106:376-383 https://doi.org/10.1093/toxsci/kfn171
- Glander HG, M Rytter and C Schonborn. 1984. Studies on the mycotic and bacterial risk of contamination and the use of nipagin in the artificial insemination of cryosperm. Zentralbl. Gynakol. 106:573-584
- Golden R, J Gandy and G Vollmer. 2005. A review of the endocrine; activity of parabens and implications for potential risks to human health. Crit. Rev. Toxicol. 35:435-458 https://doi.org/10.1080/10408440490920104
- Hagedorn-Leweke U and BC Lippold. 1995. Absorption of sunscreens and other comjpounds through human skin in vivo: derivation of a method to predict maximum fluxes. Pharm. Res. 12:1354-1360 https://doi.org/10.1023/A:1016286026462
- Hamilton JT, Y Zhou and AW Gelb. 1990. Paraben preservatives but not succinylcholine are cerebral vasodilators in vitro. Anesthesiology 73:1252-1257 https://doi.org/10.1097/00000542-199012000-00025
- Handa O, S Kokura, S Adachi, T Takigi, Y Naito, T Tanigawa, N Yoshida and T Yoshikaw. 2006. Methylparaben potentiates UV-induced damage of skin keratinocytes. Toxicol. 227:62-72 https://doi.org/10.1016/j.tox.2006.07.018
- Harvey PW. 2003. Parabens, oestrogenicity, underarm cosmetics and breast cancer: a perspective on a hypothesis. J. Appl. Toxicol. 23:285-288 https://doi.org/10.1002/jat.946
- Harvey PW. 2005. Comment on developmental toxicity evaluation of butylparaben in Sprague-Dawley rats. Birth Defects Res. B Dev. Reprod. Toxicol. 74:114-115 https://doi.org/10.1002/bdrb.20033
- Harvey PW and P Darbre. 2004. Endocrine Disrupters and Human Health: Could oestrogenic chemicals in body care cosmetics adversely affect breast cancer incidence in women? J. Appl. Toxicol. 24:167-176 https://doi.org/10.1002/jat.978
- Harvey PW and DJ Everett. 2006. Significance of the detection of esters of p-hydroxybenzoic acid (parabens) in human breast tumours. J. Appl. Toxicol. 24:1-4
- Hoberman AL, DK Schreur, T Leazer, GP Daston and P Carthew. 2008. Lack of effect of butylparaben and methyoparaben on the reproductive system in male rats. Birth Def. Res. (Part B) 83:123-133 https://doi.org/10.1002/bdrb.20153
- Hossaini A, JJ Larsen and JC Larsen. 2000. Lack of oestrogenic effects of food preservaives (parabens) in uterrotrophic assays. Food Chem. Toxicol. 38:319-323 https://doi.org/10.1016/S0278-6915(99)00160-X
- Inui M, T Adachi, S Takenaka, H Inui, M Nakazawa, M Ueda, H Watanabe, C Mori, T Iguchi and K Miyatake. 2003. Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes). Toxicology 194:43-50 https://doi.org/10.1016/S0300-483X(03)00340-8
- Inai Y, H Aoki, R Akamizu, ET Nishida and S Tokuoka. 1985. Tumorigenicity study of butyl and isobutyl p-hydroxybenzoates administered orally to mice. Food Chem. Toxicol. 23:575-578 https://doi.org/10.1016/0278-6915(85)90181-4
- Ishidate MJ and K Yoshikawa. 1980. Chromosome aberration tests with Chinese hamster cells in vitro with and without metabolic activation-A comparative study on mutagens and carcinogens. Arch. Toxicol. 4:41-44
- Jackson EM. 1992. Moisturizers of today. J. Toxicol. Cutaneous Ocul. Toxicol. 11:173-184 https://doi.org/10.3109/15569529209042706
- Janjua NR, GK Mortensen, AM Andersson, B Kongshoj, NE Skakkebaek and HC Wulf. 2007. Systemic uptake of diethyl phthalate, dibutyl phthalate, and butyl paraben following whole-body topical application and reproductive and thyroid hormone levels in humans. Environ. Sci. Technol. 41:5564-5570 https://doi.org/10.1021/es0628755
- Jian L and WP Li. 1993a. Ciliotoxicity of methyl- and propylp- hydroxy-benzoates a dose-response and surface-response study. J. Pharmacy and Pharmacol. 45:925-927 https://doi.org/10.1111/j.2042-7158.1993.tb05624.x
- Jian L and WP Li. 1993b. Kinetics evaluation of the ciliotoxicity of methyl- and propyl-p-hydroxybenzoates using factorial experiments. J. Pharmacy and Pharmacol. 45:98-101 https://doi.org/10.1111/j.2042-7158.1993.tb03691.x
-
Kang KS, JH Che, DY Ryu, TW Kim, GX Li and YS Lee. 2002. Decreased sperm number and motile activity on the F1 offspring maternally exposed to butyl
$\rho$ -hydroxybenzoic acid (butyl paraben). J. Vet. Med. Sci. 64:227-235 https://doi.org/10.1292/jvms.64.227 - Kawaquchi M, K Morohoshik, J Masuda, G Watanabe, M Morita, H Imai, K Taya and T Himi. 2009. Maternal isobutylparaben exposure decreases the plasma corticosterone level in dams and sensitivity to estrogen in female offspring rats. J Vet. Med. Sci. 71:1027-1033 https://doi.org/10.1292/jvms.71.1027
- Koda T, T Unezu, R Kamata, K Morohoshi, T Ohta and M Morita. 2005. Uterotrophic effects of benzophenone derivatives and p-hydroxybenzoate used in ultraviolet screens. Environ. Res. 98:40-45 https://doi.org/10.1016/j.envres.2004.05.015
- Lakeram M, AJ Paine, DJ Lockley, DJ Sanders, R Pendlington and B Forbes. 2006. Transesterification of p-hydroxybenzoic acid esters (parabens) by human intestinal (Caco-s) cells. Xenobiotica 36:739-749 https://doi.org/10.1080/00498250600738637
- Leite AM. 2006. Estudo de desreguladores endocrinos numa Estacao de Tratamento de Aguas Residuais (Master thesis). Vila Real: University of Tras-os-Montes and Alto Douro
- Lemini C, R Jaimez, ME Avila, Y Franco, F Larrea and AE Lemus. 2003. In vivo and in vitro estrogen bioactivities of alkyl parabens. Toxicol. Ind. Health. 19:69-79 https://doi.org/10.1191/0748233703th177oa
- Lemini C, G Silva, C Timossi, D Luque, A Valverde, M Gonzalez-Marti, A Hernandez, C Rubio-Poo, B Chavez Lara and F Valezuela. 1997. Estrogenic effects of p-hydroxybenzoic acid in CD1 mice. Environ. Res. 75:130-134 https://doi.org/10.1006/enrs.1997.3782
- Maddox GL. 1982. Three perspectives on the 1981 White House Conference on Aging. Research Geronotologist 22:126-127 https://doi.org/10.1093/geront/22.2.126
- Manawadu BR, SR Mostow and FM Laforce. 1979. Impairment of tracheal ring ciliary activity by halothane. Anesth. Analg. 58:500-504
- Martins F, A Margarida, MM Oliveira, PJ Oliveira, P Francisco and FP Peixoto. 2008. Toxicity of parabens in testis mitochondria: a possible role on male infertility. Biochim. Biophys. Acta-Bioenergetics 1777:s60-61
- Matthews C, J Davidson, E Bauer, JL Morrison and AP Richardson. 1956. p-Hydroxybenzoic acid esters as preservatives. II. Acute and chronic toxicity in dogs, rats, and mice. J. Am. Pharm. Assoc. (Baltim) 45:260-267 https://doi.org/10.1002/jps.3030450420
- McGrath KG. 2003. An earlier age of breast cancer diagnosis related to more frequent use of antiperspirants/deodorants and underarm shaving. Eur. J. Cancer Prev. 12:479-485 https://doi.org/10.1097/00008469-200312000-00006
- Mikula P, R Dobsikova, Z Svobodova and J Jarkovsky. 2006. Evaluation of xenoestrogenic potential of propylparaben in zebrafish (Danio rerio). Neuro Endocrinol. Lett. 27:104-107
- Mirick DK, S David and DB Thomas. 2002. Antiperspirant use and the risk of breast cancer. J. Natl. Cancer. Inst. 94:1578-1580 https://doi.org/10.1093/jnci/94.20.1578
- Mizuno H, H Hirai, S Kawai and T Nishida. 2009. Removal of estrogenic activity of iso-butylparaben and n-butylparaben by laccase in the presence of 1-hydroxybenzotriazole. Biodegradation 20:533-539 https://doi.org/10.1007/s10532-008-9242-y
- Nakagawa Y and P Moldeus. 1998. Mechanism of p-hydroxybenzoate ester-induced mitochondrial dysfunction and cytotoxicity in isolated rat hepatocytes. Biochem. Pharmacol. 55:1907-1914 https://doi.org/10.1016/S0006-2952(98)00097-5
- Nakagawa Y and G Moore. 1999. Role of mitochondrial membrane permeability transition in p-hydroxybenzoate esterinduced cytotoxicity in rat hepatocytes. Biochem. Pharmacol. 58:811-816 https://doi.org/10.1016/S0006-2952(99)00147-1
- Nes IF and T Eklund. 1983. The effects of paraben on DNA, RNA and protein-synthesis in Escherichia coli and Bacillus subtilis. J. Appl. Bacteriol. 54:237-242 https://doi.org/10.1111/j.1365-2672.1983.tb02612.x
- Oishi S. 2001. Effects of butylparaben on the male reproductive system in rat. Toxicol. Ind. Health 17:31-39 https://doi.org/10.1191/0748233701th093oa
- Oishi S. 2002a. Effects of propylparaben on the male reproductive system. Food Chem. Toxicol. 40:1807-1813 https://doi.org/10.1016/S0278-6915(02)00204-1
- Oishi S. 2002b. Effects of butylparaben on the male reproductive system in mice. Arch. Toxicol. 76:423-429 https://doi.org/10.1007/s00204-002-0360-8
- Oishi S. 2004. Lack of spermatotoxic effects of methyl and ethyl esters of p-hydroxybenzoic acid in rats. Food. Chem. Toxicol. 42:1845-1849 https://doi.org/10.1016/j.fct.2004.06.015
- Okamoto Y, T Hayashi, S Matsunami, K Ueda and N Kojima. 2008. Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage. Chem. Res. Toxicol 21:1594-1599 https://doi.org/10.1021/tx800066u
-
Okubo T, Y Yokoyama and I Kano. 2001. ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ER
$\alpha$ and PR. Food Chem. Toxicol. 39:1225-1232 https://doi.org/10.1016/S0278-6915(01)00073-4 - Orth DS. 1980. Use of parabens as cosmetic preservatives. Int. J. Dermatol. 19:504-505 https://doi.org/10.1111/j.1365-4362.1980.tb00369.x
- Paxeus N. 1996. Organic pollutants in the effluents of large wastewater treatment plants in Sweden. Water Res. 30:1115-1122 https://doi.org/10.1016/0043-1354(95)00278-2
- Pedersen KL, SN Pedersen, LB Christiansen, B Korsgaard and P Bjerregaard. 2000. The preservatives ethyl-, propyl- and butylparaben are oestrogenic in an in vivo fish assay. Pharmacol. Toxicol. 86:110-113 https://doi.org/10.1034/j.1600-0773.2000.d01-20.x
- Prusakiewicz JJ, HM Harville, Y Zhang, C Ackermann and RL Voorman. 2007. Parabens inhibit human skin estrogen sulfotransferase activity: possible link to paraben estrogenic effects. Toxicology 232:248-256 https://doi.org/10.1016/j.tox.2007.01.010
- Pugazhendhi D, AJ Sadler and PD Darbre. 2007. Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17beta-oestradiol in MCF7 human breast cancer cells. J. Appl. Toxicol. 2:67-77
- Rastogi SC, A Schouten, N de Kruijf and JW Weijland. 1995. Contents of methyl-, ethyl-, propyl-, butyl- and benzylparaben in cosmetic products. Contact Derm. 32:28-30 https://doi.org/10.1111/j.1600-0536.1995.tb00836.x
- Routledge EJ, J Parker, J Odum, J Ashby and JP Sumpter. 1998. Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic. Toxicol. Appl. Phrmacol. 153:12-19 https://doi.org/10.1006/taap.1998.8544
- Sabalitschka T and R Neufeld-Crzelliter. 1954. Behavior of phydroxybenzoic acid in human body. Arzneimittel-Forsch. 4:575-579
- Sado I. 1973. Synergistic toxicity of official permissible preservative food additives, Jap. J. Hygiene 28:463-476 https://doi.org/10.1265/jjh.28.463
- Sharpe RM and NE Skakkebaek. 1993. Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 341:1392-1395 https://doi.org/10.1016/0140-6736(93)90953-E
- Shaw J and D de Catanzaro. 2009. Estrogenicity of parabens revisited: impact of parabens on early pregnancy and an uterotrophic assay in mice. Reprod. Toxicol. 28:26-31 https://doi.org/10.1016/j.reprotox.2009.03.003
- Sheu CW, D Salomon, JL Simmons, T Sreevalsan and E Freese. 1975. Inhibitory effects of lipophilic acids and related compounds on bacteria and mammalian cells. Anrimicrob. Agents Chemotherapy 7:349-363 https://doi.org/10.1128/AAC.7.3.349
- Sokol H. 1952. Recent developments in the preservations of pharmaceuticals. Drug Standards 20:89-106
- Song BL, HY Li and DR Peng. 1989. In vitro spermicidal activity of parabens against human-spermatozoa. Contraception 39:331-335 https://doi.org/10.1016/0010-7824(89)90065-6
- Song BL, DR Peng, HY Li, GH Zhang, J Zhang, KL Li and TQ Zhao. 1991. Evaluation of the effect of butyl p-hydroxybenzoate on the proteolytic activity and membrane function of human spermatozoa. J. Reprod. Fertil. 91:435-440 https://doi.org/10.1530/jrf.0.0910435
- Soni MG, GA Burdock, SL Taylor and NA Greenberg. 2001. Safety assessment of propyl paraben: a review of the published literature. Food Chem. Toxicol. 39:513-532 https://doi.org/10.1016/S0278-6915(00)00162-9
- Soni MG, SL Taylor, NA Greenberg and GA Burdock. 2002. Evaluation of the health aspects of methyl paraben: a review of the published literature. Food Chem. Toxicol. 40:1335-1373 https://doi.org/10.1016/S0278-6915(02)00107-2
- Soni MG, IG Carabin and GA Brdock. 2005. Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food Chem. Toxicol. 43:985-1015 https://doi.org/10.1016/j.fct.2005.01.020
- Soto AM, C Sonnenschein, KL Chung, MF Fernandez, N Olea and FO Serrano. 1995. The E-screen assay as a tool to identify estrogens:an update on estrogenic environmental pollutants. Environ. Health Perspect. 103:113-122
- Tavares RS, FC Martins, PJ Oliveira, J Ramalho-Santos and FP Peixoto. 2009. Parabens in male infertility-Is there a mitochondrial connection? Reprod. Toxicol. 27:1-7 https://doi.org/10.1016/j.reprotox.2008.10.002
- Taxvig C, AM Vinggaard, U Hass, M Axelstad, J Boberg, PR Hansen, H Frederiksen and C Nellemann. 2008. Do paragens have the ability to interfere with steroidogenesis? Toxicol. Sci. 106:206-213 https://doi.org/10.1093/toxsci/kfn148
- Terasaki M, M Makino and N Tatarazako. 2009. Acute toxicity of parabens and their chlorinated by-products with Daphnia magna and Vibrio fischeri bioassays. J. Appl. Toxicol. 29:242-247 https://doi.org/10.1002/jat.1402
- Tsukamoto H and S Terada. 1964. Metabolism of drugs. XLVII. Metabolic fate of p-hydroxybenzoic acid and its derivatives in rabbits. Chemical and Pharmaceutical Bull. 12:765-769 https://doi.org/10.1248/cpb.12.765
- Verma RJ and V Asnani. 2007. Ginger extract amiliorates paraben induced biochemical changes in liver and kidney of mice. Acta. Pol. Pharm. 64:217-220
- Vo TT and EB Jeung. 2009. An evaluation of estrogenic activity of parabens using uterine calbindin-D9K gene in an immatuve rat model. Toxicol. Sci. 112:68-77 https://doi.org/10.1093/toxsci/kfp176