한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)

  • 제22권1호
  • /
  • Pages.181-194
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  • 2009
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  • 1738-6640(pISSN)
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  • 2234-4020(eISSN)
대한한방안이비인후피부과학회 (The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology)
권호 표지

한약 성분 함유 기능성 비누 가이아 1400의 족부 백선 개선에 대한 임상 연구

A pilot test on the effects of improvement on Tinea pedis by using functional soap Gaia 1400, containing medicinal herbs

  • 정달림 (동국대학교 한의과대학 안이비인후피부과학교실) ;
  • 홍승욱 (동국대학교 한의과대학 안이비인후피부과학교실)
  • 발행 : 2009.04.25
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초록

Objectives : This clinical research was conducted to test Patients with Tinea Pedis by using functional soap Gaia 1400, containing medicinal herbs Methods : Total 24 patients who visited Oriental Medical Ophthalmology & Otolaryngology & Dermatology of Dongguk Ilsan Hospital from June 17th, 2008 to November 11th, 2008. They used functional soap daily during 8 weeks. We Observed change of erythema, scaling, vesicle, pustule, exudate, crust and pruritus after 4weeks and 8 weeks. Also Clinical evaluation I, II were used to evaluate the effects of Gaia 1400. Results : 1. There were no significant differences on sex, age and onset. 2. Statistically. After treatment(4,8weekes) Tinea Pedis symptoms score showed significant effect on Tinea Pedis. And the score of using Gala 1400 after 8 weeks is lower than 4 weeks. 3. After 8weeks of treatment, Gaia 1400 showed meaningful effect on Clinical global evaluation I, II. 4. Tinea Pedis Exacerbated in a case after using Gaia 1400 and in the 4 cases Skin dryness Incerased. Conclusion : Considering the above results, we can speculate that functional soap Gaia 1400, containing medicinal herb has some therapeutical effects in mitigating the symptoms of Tenia Pedis.

키워드

참고문헌

  1. 대한피부과학회. 피부과학. 개정 4판. 서울: 여문각. 2001:315-6.
  2. 안성구, 이승헌, 박윤기, 흔히 보는 피부질환. 서울 : 고려의학. 1993:105-11.
  3. Rogers D, Kilkenny M, Marks R. The descriptive epidemiollogy of tinea pedis in the community. The descriptive epidermiology of tine pedis in the community. Australas. J. Dermatol. 1996;37:178-84. https://doi.org/10.1111/j.1440-0960.1996.tb01049.x
  4. 강형근 이원주 전재복 구대원, 강원도 98군사병들에서 백선증의 임상 및 균학적 관찰, 대한피부과학회지 2001;39(8):872-7.
  5. Gupta AK, et al; Antifungal agents: An overview. Part II. J of Am Acad Dermatol 1994;30:911-33. https://doi.org/10.1016/S0190-9622(94)70112-1
  6. 강원형. 피부질환 아틀라스. 서울: 한미의학. 2002:271-5.
  7. Brookman SD, Bullen MU, Marley J, Ellis DH, Williams T, Barnetson RS, Patel A. Topical treatment of interdigital tinea pedis: terbinafine compared with clotrimazole., Australas J Dermatol. 1999;40(4):197-200. https://doi.org/10.1046/j.1440-0960.1999.00360.x
  8. Barnetson RS, Marley J, Bullen M, Brookman S, Cowen P, Ellis D, Williams T. Comparison of one week of oral terbinafine (250 mg/day) with four weeks of treatment with clotrimazole 1% cream in interdigital tinea pedis. British Journal of Dermatology 1998;139:675-8. https://doi.org/10.1046/j.1365-2133.1998.02466.x
  9. 강정수. 피부진균증의 한의학적 고찰. 동의생리병리학회지, 2006;20(4):799-806.
  10. Monica K. Bedi, MD; Philip D. Shenefelt, MD, Herbal Therapy in Dermatology. Arch Dermatol. 2002;138:232-42. https://doi.org/10.1001/archderm.138.2.232
  11. 도정애. 택사의 항균 및 항진균 작용에 관한연구. 생약학회지. 1996;27(4):378-82.
  12. 천승철, 지선영, 이상곤. 내소황련탕 및 구성약물의 항균활성에 관한 실험적 연구. 대한본초학회지. 2004;60(10):51-60.
  13. Ledezma E, Marcano K, Jorquera A, et al. Efficacy of ajoene in the treatment of tinea pedis: A double-blind and comparative study with terbinafine. J Am Acad Dermatol 2000;43:829-32. https://doi.org/10.1067/mjd.2000.107243
  14. 周玉朱; External Application of Lifeng Powder(藜风散)in Treating 76 Patients with Tinea Manus et Pedis, 周玉朱; Chinese Journal of Integrated Traditional and Western Medici, 中国中西医结合杂志(英文版), 编辑部邮箱 2000年 01期
  15. 안창석, 유창길, 이동주, 권기록. 봉약침요법을 통한 족부 백선 환자 1례에 대한 증례보고. 대한침구학회 임상논문집 2003:23-9.
  16. 대한피부과학회. 족부백선에 대한 Terbinafine 경구요법의 치료효과. 대한화학요법학회지 제14권 제2호 1996;1(2):225-30.
  17. Short-duration topical treatment of tinea pedis using terbinafine emulsion gel: results of a dose-ranging clinical trial. IAN G.JAMES, YOLANDA LORIA-KANZA & THOMAS C. JONES. Journal of Dermatological Treatment. 2007;18:163-8. https://doi.org/10.1080/09546630701247971
  18. de Chauvin MF, Viguié-Vallanet C, Kienzler JL, Larnier C. Novel, single-dose, topical treatment of tinea pedis using terbinafine: results of a dose-finding clinical trial. Mycoses. 2008;Jan51(1):1-6.
  19. 장일식 외 편저. 동양의약과학대전 I권. 서울 대학교 천연물과학연구소 문헌정보학연구실. 2003 : 36. 89. 136. 158. 165. 168. 171. 183. 238. 266. 273. 328. 399. 454.
  20. Habashy RR, Abdel-Naim AB, Khalifa AE, Al-Azizi MM. Anti-inflammatory effects of jojoba liquid wax in experimental models.1: Pharmacol Res. 2005;Feb(2):95-105.
  21. Graf J.Herbal anti-inflammatory agents for skin disease Skin Therapy Lett. 2000; 5(4):3-5.
  22. Rahman S, Bhatia K, Khan AQ, Kaur M, Ahmad F, Rashid H, Athar M, Islam F, Raisuddin S. Topically applied vitamin E prevents massive cutaneous inflammatory and oxidative stress responses induced by double application of 12-O-tetradecanoylphorbol- 13-acetate (TPA) in mice. Chem Biol Interact. 2008 Apr 15;172(3):195-205. Epub 2008 Jan 4.
  23. 최규동, 권영규. 족부 백선균의 한방치료제 개발을 위한 연구. 대한외관과학회지. 2002;13(1):267-24.
  24. 안성구. 이승헌, 박윤기. 흔히 보는 피부질환. 서울: 고려의학. 1993:105-11.
  25. 陳實功. 外科正宗. 上海 : 상해과학기술출판사.1989:316-8.
  26. 顧伯康 主編. 中醫外科學. 北京: 人民衛生出版社. 1987:261-2.
  27. 上海中醫學院編.中醫外科學.香蒲: 商務印書館香蒲分館. 1976:122-4.