Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
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A CASE REPORT ; BROWN TUMOR OF THE MAXILLA AND MANDIBLE IN ASSOCIATION WITH PRIMARY HYPERPARATHYROIDISM

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  • Lee, Ju-Kyung (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chonbuk National University) ;
  • Cho, Sung-Dae (Department of Oral Pathology, School of dentistry, Chonbuk National University. Institute of Oral Bio-Science, Chonbuk National University) ;
  • Leem, Dae-Ho (Department of Oral & Maxillofacial Surgery, School of Dentistry, Chonbuk National University)
  • 이주경 (전북대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 조성대 (전북대학교 치의학전문대학원 구강병리학교실, 전북대학교 구강생체과학연구소) ;
  • 임대호 (전북대학교 치의학전문대학원 구강악안면외과학교실)
  • Published : 2009.01.31
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Abstract

The brown tumors develop in bone and it develop on various area which in clavicle, rib bone, cervical bone, iliac bone etc. The development on the maxillofacial region is rare, relatively more develop on the mandible. The brown tumor directly develop by the dysfunction of calcium metabolism according to hyperparathyroidism and differential diagnosis with other bone lesion should be difficult if it would diagnose by only radiographic features. The histological feature is that proliferation of spindle cells with extravasated blood and haphazardly arranged, variably sized, multinucleated giant cell is seen. The brown tumor is firm diagnosed by physical examination, because of these histological feature show similar with other giant cell lesions(giant cell granuloma, aneurysmal bone cyst, cherubism). The brown tumors have been described as resulting from an imbalance of osteoclastic and osteoblastic activity. It result in bone resorption and fibrous replacement of the bone. So these lesions represent the terminal stage of hyperparathyroidism-dependent bone pathology. Therefore, it is the extremely rare finding that brown tumor in the facial bone as the first manifestation of an hyperparathyroidism. We experience 1 case of brown tumor(50 years old female) that developed on Maxilla and mandible with no history of hyperparathyroidism. So we report this case with a literature review.

Keywords

References

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