Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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A Case of Toxic Shock Syndrome Caused by Methicillin-resistant Staphylococcus aureus(MRSA) Following a Burn Injury

화상 후 속발한 메티실린 내성 포도알균에 의한 독성 쇼크 증후군 1례

  • Choi, Jin Hyoung (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Choi, Jae Hong (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Dae Il (Department of Pediatrics, Seoul National University College of Medicine) ;
  • Kim, Jae Seok (Department of Laboratory Medicine, Hallym University College of Medicine) ;
  • Choi, Eun Hwa (Department of Pediatrics, Seoul National University College of Medicine)
  • 최진형 (서울대학교 의과대학 소아과학교실) ;
  • 최재홍 (서울대학교 의과대학 소아과학교실) ;
  • 김대일 (서울대학교 의과대학 소아과학교실) ;
  • 김재석 (한림대학교 의과대학 진단검사의학과학교실) ;
  • 최은화 (서울대학교 의과대학 소아과학교실)
  • Received : 2009.08.29
  • Accepted : 2009.10.19
  • Published : 2009.12.25
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Abstract

Staphylococcal toxic shock syndrome (TSS) is a severe systemic illness caused by toxins produced by Staphylococcus aureus. We report a case of staphylococcal TSS in a 16 month-old boy who presented with high fever, vomiting, skin rash, and shock after a burn injury. He was managed with intravenous vancomycin, fresh frozen plasma, and intravenous immunoglobulin. Methicillin-resistant S. aureus (MRSA) was isolated from the burn wound site and anterior nostril of the patient. In addition, the MRSA isolate was genetically characterized.

독성 쇼크 증후군은 황색 포도알균 등에서 생성하는 독소에 의한 고열, 발진 및 쇼크에 병발하는 다발성 장기 부전이 발생하는 증후군이다. 저자들은 화상 후 속발한 독성 쇼크 증후군으로 진단한 환아를 vancomycin, 신선 냉동 혈장, 정맥내면역 글로불린 투여로 치료하고, 화상 부위에서 동정된 CAMRSA의 분자 생물학 및 유전적 특징을 분석하여 이를 보고하는 바이다.

Keywords

References

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