The Journal of the Acoustical Society of Korea

The Acoustical Society of Korea (한국음향학회)
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Primary Radiation Force to Ultrasound Contrast Agents in Propagating and Standing Acoustic Field

  • Seo, Jong-Bum (Department of Biomedical Engineering, Yonsei University)
  • Published : 2009.03.31
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Abstract

Primary radiation force on ultrasound contrast agents (UCA) in a propagating and standing acoustic field was explored. A specific ultrasound contrast agent $Albunex^{(R)}$ and $Optison^{(R)}$ were chosen for simulation. The model was developed based on a shelled bubble model proposed by Church. The numerical simulation suggests that bubble translational motion is more significant in therapeutic ultrasound due to higher intensity and long pulse duration. Even a single cycle of a propagating wave of 4 MPa at 1 MHz can cause a bubble translational motion of greater than $1{\mu}m$ which is approximately one tenth of capillary. Hence, UCA characteristics can be significantly changed in therapeutic ultrasound without rapid bubble collapses.

Keywords

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