Journal of Periodontal and Implant Science

  • 제39권1호
  • /
  • Pages.103-108
  • /
  • 2009
  • /
  • 2093-2278(pISSN)
  • /
  • 2093-2286(eISSN)
대한치주과학회 (Korean Academy of Periodontology)
권호 표지

치은비대에서 비외과적 치료의 효과

The effect of non-surgical treatment in gingival enlargement

  • 김상준 (강릉대학교 치과대학 치주과학교실) ;
  • 이재관 (강릉대학교 치과대학 치주과학교실) ;
  • 엄흥식 (강릉대학교 치과대학 치주과학교실) ;
  • 장범석 (강릉대학교 치과대학 치주과학교실)
  • Kim, Sang-Jun (Department of Periodontology, School of Dentistry, Kangnung National University) ;
  • Lee, Jae-Kwan (Department of Periodontology, School of Dentistry, Kangnung National University) ;
  • Um, Heung-Sik (Department of Periodontology, School of Dentistry, Kangnung National University) ;
  • Chang, Beom-Seok (Department of Periodontology, School of Dentistry, Kangnung National University)
  • 발행 : 2009.03.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Purpose: It is well recognized that gingival enlargement is induced by unwanted effect associated with three major drugs/drug groups - phenytoin, cyclosporine, and the calcium channel blockers. The present case report describes the effect and limitation of non-surgical treatment in gingival enlargement cases. Materials and methods: Three cases included 2 drug-influenced gingival enlargement patients and a idiopathic gingival fibromatosis patient. For the drug-influenced gingival enlargement patients, the medication was replaced with other medication. And then, all the patients were treated non-surgically. Results: Drug-influenced gingival enlargements had been reduced after non-surgical treatment and the results were well-maintained. In the idiopathic gingival fibromatosis case, non-surgical treatment resulted in only limited reduction of gingival enlargement, and surgical periodontal treatment was unavoidable. Conclusion: These case reports indicated that non-surgical periodontal treatment with change in medication was effective in the treatment of drug-influenced gingival enlargements. Non-surgical approach can be considered as the primary management to reduce the gingival enlargement. If non-surgical treatment encounters a limitation, surgical treatment should be considered.

키워드

참고문헌

  1. Newman MG, Takei HH, Klokkevold PR, Carranza FA. Carranza's Clinical Periodontology, 10th ed. Philadelphia: W.B. Saunders; 2006:373-390
  2. Rees TD, Levine RA. Systemic drugs as a risk factor for periodontal disease initiation and progression. Compend Contin Educ Dent 1995;16:20-42
  3. Lewis IK, Hanlon JT, Schmader KE et al. Use of medications with potential oral adverse drug interactions in community-dwelling elderly. Spec Care Dentist 1993;13: 171-176 https://doi.org/10.1111/j.1754-4505.1993.tb01470.x
  4. Academy report: Drug-associated gingival enlargement. J Periodontol 2004;75:1424-1431 https://doi.org/10.1902/jop.2004.75.10.1424
  5. Kim WK, Baek J, Lee YK. The effect of periodontal therapy on the gingival thickness in patients with drug-induced gingival enlargement. J Korean Acad Periodontol 2005;35(4) :1109-1116 https://doi.org/10.5051/jkape.2005.35.4.1109
  6. Casetta I, Granieri E, Desidera M et al. Phenytoin-induced gingival overgrowth: A community-based cross-sectional study in Ferrara, Italy. Neuroepidemiology 1997;16:296-303 https://doi.org/10.1159/000109700
  7. Boltchi FE, Rees TD, Iacopino AM. Cyclosporine A-induced gingival overgrowth: A comprehensie review. Quintessence lnt 1999;30:775-783
  8. Barak S, Engelberg I, Hiss Z. Gingival hyperplasia caused by nifedipine: Histopathological findings. J Periodontol 1987;58:639-642 https://doi.org/10.1902/jop.1987.58.9.639
  9. Nakou M, Kamma n, Andronikaki A, Mitsis F. Subgingival microflora associated with nifedipine-induced gingival overgrowth. J Periodontol 1998;69:664-669 https://doi.org/10.1902/jop.1998.69.6.664
  10. Fu E, Nieh S, Wikesjo UM, The effect of plaque retention on cyclosprine-induced gingival overgrowth in rats. J Periodontol 1997;68:92-98 https://doi.org/10.1902/jop.1997.68.1.92
  11. Mavrogiannis M, Ellis JS, Thomason JM, Seymour RA. The management of drug-induced gingival overgrowth. J Clin Periodontol 2006;33:433-439
  12. Somacarrera ML, Lucas M, Scully C et al. Effectiveness of periodontal treatments on cyclosporine-induced gingival overgrowth in transplant patients. British Dental Journal 1997;183:89-94 https://doi.org/10.1038/sj.bdj.4809430
  13. Aimetti M, Romano F, Marsico A, Navone R. Non-surgical periodontal treatment of cyclosporin A-induced gingival overgrowth: immunohistochemical results. Oral Dis 2008;14(3): 244-250 https://doi.org/10.1111/j.1601-0825.2007.01364.x
  14. Seymour RA, Smith DG. The effect of a plaque control programme on the incidence and severity of cyclosporin- induced gingival changes. J Clin Periodontol 1991;18: 107-110 https://doi.org/10.1111/j.1600-051X.1991.tb01698.x
  15. Hancock RH, Swan RH. Nifedipine-induced gingival overgrowth. J Clin Periodontol 1992;19: 12-14 https://doi.org/10.1111/j.1600-051X.1992.tb01141.x
  16. Ellis IS, Seymour Ra, Steele JG et al. Prevalence of gingival overgrowth induced by calcium channel blockers: A community-based study. J Periodontol 1999;70:63-67 https://doi.org/10.1902/jop.1999.70.1.63