Previous Tracheotomy as a Prognostic Factor in Advanced Laryngeal Cancer

치료 전 시행된 기관절개술이 진행된 후두암에 미치는 영향

  • Song, Chan-Il (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of UIsan) ;
  • Han, Ju-Hee (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of UIsan) ;
  • Choi, Seung-Ho (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of UIsan) ;
  • Kim, Sang-Yoon (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of UIsan) ;
  • Nam, Soon-Yuhl (Department of Otolaryngology, Asan Medical Center, College of Medicine, University of UIsan)
  • 송찬일 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 한주희 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 최승호 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 김상윤 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 남순열 (울산대학교 의과대학 서울아산병원 이비인후과학교실)
  • Published : 2009.12.30

Abstract

Background and Objectives : Obstructive laryngeal cancers have to be managed with tracheostomy, which has been reported with increased local or stomal recurrence. Stomal recurrence after treatment of laryngeal cancer is one of the most serious issues in the management of laryngeal cancer. Prognosis of locally advanced laryngeal cancer in patients with previous tracheostomy is evaluated. Materials and Methods : Between 1996 and 2007, 174 patients with previously untreated advanced laryngeal cancer(stage III, IV) were enrolled. Overall survival(OS) and disease specific survival(DSS) according to the presence of previous tracheostomy were compared. OS and DSS of the groups with different duration from tracheostomy to treatment were compared. Results : Among 174 patients with advanced laryngeal cancer, previous tracheostomy was performed in 24 patients. Of 24 patients, there were stomal recurrences in 5 patients. DSS of previous tracheostomy group and that of the other group were statistically different(p=0.001). There was statistical significant difference between OS of groups which start treatment more than 14 days after tracheostomy and within 14 days(p=0.03). Conclusions : If possible, Previous tracheostomy should be avoided and if it is inevitable, the elective treatment should be recommended at least within 2 weeks.

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