생물정신의학 (Korean Journal of Biological Psychiatry)

  • 제16권4호
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  • Pages.256-265
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  • 2009
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  • 1225-8709(pISSN)
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  • 2005-7571(eISSN)
대한생물정신의학회 (The Korean Society of Biological Psychiatry)
권호 표지

외상 후 스트레스 장애 동반 여부에 따른 정신분열병 환자의 임상증상과 치료효과의 비교 : 1년간의 전향적 추적연구

Comorbidity of Posttraumatic Stress Disorder and Its Effect on Treatment Outcomes in Patients with Schizophrenia : One-Year Prospective Follow-Up Study

  • 박성종 (서울특별시 은평병원 정신과) ;
  • 김남희 (서울특별시 은평병원 정신과) ;
  • 정재열 (서울특별시 은평병원 정신과) ;
  • 이선이 (서울특별시 은평병원 정신과)
  • Park, Sung-Jong (Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital) ;
  • Kim, Nam Hee (Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital) ;
  • Jeong, Jae-Yeol (Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital) ;
  • Lee, Sunny (Department of Psychiatry, Seoul Metropolitan Eunpyeong Hospital)
  • 발행 : 2009.11.30
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초록

Objectives : The aims of this study were to assess a) the prevalence of trauma and posttraumatic stress disorder(PTSD) in schizophrenic patients and b) the differences in symptomatology and outcome after 1year treatment between those with and without PTSD. Methods : Twenty eight schizophrenia and schizoaffective disorder patients completed the Positive and Negative Syndrome Scale(PANSS), Life Stressor Checklist-Revised(LSCL-R), Clinician-Administered PTSD Scale(CAPS), Dissociative Experiences Scale(DES), Hamilton Psychiatry Rating Scale for Depression(HAM-D), and Rosenberg Self-Esteem Scale(RSE). Results : Twenty six patients(92.9%) had at least one trauma in their life time. Eleven patients(39.3%) were diagnosed with PTSD. PTSD group had significantly higher scores on HAM-D and DES but lower scores on RSE. PTSD group also had significantly lower score in the baseline PANSS Negative score. Higher CAPS scores were significantly correlated with lower baseline PANSS Negative score and greater change after 1year of PANSS Negative score. Conclusion : These results showed that the prevalences of trauma and PTSD are high in schizophrenic patients and suggested that PTSD and trauma-related symptoms affected the symptomatology and treatment outcome. More research is warranted to better understand the effects of PTSD in schizophrenic patients.

키워드

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