A Discrepancy between $^{131}I$-Metaiodobenzylguanidine ($^{131}I$-MIBG) Scintigraphy and $^{18}F$-FDG PET/CT after $^{131}I$-MIBG Therapy in a Patient with Recurred Malignant Pheochromocytoma

재발한 악성 갈색세포종 환자에서 $^{131}I$-Metaiodobenzylguanidine ($^{131}I$-MIBG) 치료 후 $^{131}I$-MIBG와 $^{18}F$-FDG PET/CT 영상의 차이점

  • Kim, Kun-Ho (Department of Nuclear Medicine, Chungnam National University Hospital) ;
  • Kim, Seong-Min (Department of Nuclear Medicine, Chungnam National University Hospital) ;
  • Seo, Young-Duk (Department of Nuclear Medicine, Chungnam National University Hospital)
  • Published : 2009.12.30

Abstract

A 59-year-old woman who was diagnosed with malignant pheochromocytoma underwent $^{18}F$-fluorodeoxyglucose positron emission tomography/computed tomography ($^{18}F$-FDG PET/CT). She had undergone left adrenalectomy for pheochromocytoma 4 years previously. Recent multiple metastatic pulmonary nodules were noted on the chest X-ray. After treatment with $^{131}I$-metaiodobenzylguanidine ($^{131}I$-MIBG) with 7.4 GBq, post-therapy $^{131}I$-MIBG scintigraphy depicted multiple distant metastases including lung, liver, abdominal para-aortic and mesenteric lymph nodes. $^{18}F$-FDG PET/CT also depicted multiple metastases in lung, liver, and abdominal para-aortic lymph nodes, but some lesions were not shown. In this case, $^{131}I$-MIBG scintigraphy found additional lesions in metastatic malignant pheochromocytoma.

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