PROPOSAL FOR PRETREATMENT OF PATIENTS IN ANTIPLATELET THERAPY REQUIRING MINOR ORAL SURGERY

항혈소판제 복용 환자의 구강 내 소수술 전 처치에 대한 제안

  • Choi, Ji-Wook (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Choi, Se-Kyung (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Nam-Kyun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Choi, Eui-Young (Department of Internal medicine, College of Medicine, Yonsei University) ;
  • Cha, In-Ho (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University) ;
  • Kim, Hyung-Jun (Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University)
  • 최지욱 (연세대학교 치과대학 구강악안면외과학 교실) ;
  • 최세경 (연세대학교 치과대학 구강악안면외과학 교실) ;
  • 김남균 (연세대학교 치과대학 구강악안면외과학 교실) ;
  • 최의영 (연세대학교 의과대학 내과학 교실) ;
  • 차인호 (연세대학교 치과대학 구강악안면외과학 교실) ;
  • 김형준 (연세대학교 치과대학 구강악안면외과학 교실)
  • Published : 2009.12.31

Abstract

Purpose: Many patients in anti-platelet therapy have been consulted for bleeding risks before minor oral surgery. However, there has not been an established pretreatment protocol for treating these patients. The purpose of this study is to make a protocol for the preoperative management for patients in anti-platelet therapy. Patients and Methods: The existed consultation pattern of patients was examined in the Department of Oral and Maxillofacial Surgery, Yonsei Dental Hospital. Based on the observation, a protocol including classification of medical status of patients and the type of oral surgery in need was introduced. This protocol had been performed for 6 months. Result: Following this protocol, the frequency of consultation for bleeding risk was decreased. The number of minor oral surgeries with concurrent anti-platelet therapy was increased. There was no severe bleeding event observed among minor oral surgeries that were performed while maintaining anti-platelet therapy. Conclusion: This protocol can be used as a guideline for clinical practice of patients in anti-platelet therapy requiring minor oral surgery.

Keywords

References

  1. Perez-Gomez F, Alegria E, Berjon J, Iriarte JA, Zumalde J, Salvador A, et al. Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation A randomized multicenter study. J Am Coll Cardiol 2004;44:1557-1566 https://doi.org/10.1016/j.jacc.2004.05.084
  2. Owens CD BM. Thrombosis and coagulation : operative management of the anticoagulanted patient. Surg Clin North Am 2005;85:1779-189
  3. Little JW, Miller CS, Henry RG, McIntosh BA. Anltithrombotic agents: implications in dentistry. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:544-51 https://doi.org/10.1067/moe.2002.121391
  4. McNeely W, Goa KL. Triflusal. Drugs 1998;55:823-833 https://doi.org/10.2165/00003495-199855060-00011
  5. Hirsh J, Dalen JE, Deykin D, Poller L. Oral anticoagulants. Mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 1992;102:312S-26S
  6. Wahl MJ. Dental surgery in anticoagulated patients. Arch Intern Med 1998;158:1610-6 https://doi.org/10.1001/archinte.158.15.1610
  7. Dodson TB. Strategies for managing anticoagulated patients requiring dental extractions: an exercise in evidence-based clinical practice. J Mass Dent Soc 2002;50:44-50
  8. Blinder D, Manor Y, Martinowitz U, Taicher S. Dental extractions in patients maintained on oral anticoagulant therapy: comparison of INR value with occurrence of postoperative bleeding. Int J Oral Maxillofac Surg 2001;30:518-21 https://doi.org/10.1054/ijom.2001.0172
  9. Miloro M, Peterson's Principles of Oral and Maxillofacial Surgery. 2nd ed. London: BC Decker, 2004
  10. Beirne OR. Evidence to continue oral anticoagulant therapy for ambulatory oral surgery. J Oral Maxillofac Surg 2005;63:540-5 https://doi.org/10.1016/j.joms.2004.12.009
  11. McIntyre H. Management, during dental surgery, of patients on anticoagulants. Lancet 1966;2:99-100
  12. Wahl MJ. Myths of dental surgery in patients receiving anticoagulant therapy. J Am Dent Assoc 2000;131:77-81 https://doi.org/10.14219/jada.archive.2000.0024