Journal of The Korean Dental Society of Anesthesiology (대한치과마취과학회지)

The Korean Dental Society of Anesthsiology (대한치과마취과학회)
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Paradoxical Reaction to Midazolam Used in Intravenous Sedation for Dental Treatment -Report of a Case and Review of the Literature-

치과치료를 위한 정주진정법에 사용되는 미다졸람에 대한 역설적 반응 -증례 보고 및 문헌고찰-

  • Jeon, Jae-Yun (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University) ;
  • Jung, Se-Hwa (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University) ;
  • Lee, Byung-Ha (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University) ;
  • Im, Jae-Jung (Division of Orthodontics, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Hwang, Kyung-Gyun (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University) ;
  • Shim, Kwang-Sup (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University) ;
  • Park, Chang-Joo (Division of Oral and Maxillofacial Surgery, College of Medicine, Hanyang University)
  • 전재윤 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 정세화 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 이병하 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 임재중 (한양대학교 의과대학 치과학교실 치과교정과) ;
  • 황경균 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 심광섭 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 박창주 (한양대학교 의과대학 치과학교실 구강악안면외과)
  • Published : 2009.12.30
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Abstract

Midazolam, one of the most common benzodiazepine derivatives, is widely used in intravenous sedation for dental treatment without severe complications. However, paradoxical reactions to midazolam, including patient's unanticipated restlessness, agitation, hostility, and rage, have been frequently reported since the introduction of benzodiazepine. During outpatient intravenous sedation using midazolam for dental treatment, we experienced a paradoxical reaction to midazolam in a 28-year-old female patient. With a thorough review of the literature, the management of this complication and its various etiologies were discussed.

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