한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제26권6호
  • /
  • Pages.650-654
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  • 2009
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

한우 송아지에서 세균성 뇌막염의 자기공명영상

Magnetic Resonance Imaging Feature of Bacterial Meningitis in a Neonate Hanwoo Calf

  • Cho, Young-Kwon (Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chonbuk National University) ;
  • Kim, Jin-Won (Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chonbuk National University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University) ;
  • Lee, Ki-Chang (Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chonbuk National University)
  • 발행 : 2009.12.31
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초록

일주령 20 kg 한우 송아지가 급성으로 침울, 보행실조, 횡와위 그리고 진전을 보여 전북대학교 전북동물의료센터로 내원하였다. 시력소실과 각막부종도 관찰되었다. 안구진탕과 사시 그리고 후궁반장까지 보이는 등 점점 증상은 악화되었다. 혈액검사 결과 뚜렷한 백혈구 증가증 및 저알부민혈증과 BUN증가를 관찰하였다. 단순방사선검사에서는 특이소견이 관찰되지 않았다. 자기공명영상 검사 결과 측뇌실, 제3뇌실 그리고 제4뇌실의 확장을 관찰하였으며 대뇌 좌측 측두엽의 피질과 백질 부위에 국소적으로 T1강조영상에서 저신호로 T2강조영상에서 고신호로 그리고 조영T1강 조영상에서 미약하지만 조영증강효과가 관찰되었다. 뇌척수액 검사결과 대장균 감염이 확인되었다. 환자는 치료에 반응하지 않고 입원 3일 후 폐사하였다. 조직병리학적 검사에서 대장균 감염에 의한 심각한 다발성 섬유-화농성 뇌막염으로 확진되었다.

A 1-week-old, male Korean native calf with acute clinical signs of depression, mild diarrhea, ataxia, recumbency and tremor was referred to Chonbuk Veterinary Medical Center of Chonbuk National University. Vision loss and cornea edema were also observed on physical examination. The patient had been deteriorated with nystagumus, strabisumus and opisthtonus. Blood cell count test and blood biochemistry test revealed remarkable leukocytosis, and hypoalbuminemia and increased blood urea nitrogen. No remarkable findings were observed on radiography. On magnetic resonance imaging study, there were enlarge lateral, third, and forth ventricles. The cortical grey and subcortical white matter of left temporal lobe showed hypointense on T1-weighted images and hyperintense on T2-weighted images, and slightly enhanced on contrast-enhanced T1-weighted images. Escherichia coli strain was identified from cerebrospinal fluid sample. Palliative treatment was attempted but the neonatal calve was expired three days after admission. Severe multifocal fibrino-suppurative meningitis with Escherichia coli infection was confirmed histopathologically.

키워드

참고문헌

  1. Aldridge BM, Garry FB, Adams R. Neonatal septicemia in calves: 25 cases (1985-1990). J Am Vet Med Assoc 1993; 203(9): 1324-1329
  2. Bagley RS. Multifocla Neurologic Disease. In: Textbook of Veterinary Internal Medicine 6^{th} ed. Missouri: Elsevier Saunders. 2005: 836-842
  3. Dow SW, LeCouteur RA, Henik RA, Jones RL, Poss ML. Central nervous system infection associated with anaerobic bacteria in two dogs and two cats, J Vet Intern Med 1988; 2(4): 171-176 https://doi.org/10.1111/j.1939-1676.1988.tb00312.x
  4. Fecteau G, Smith BP, George LW. Septicemia and meningitis in the newborn calf. Vet Clin North Am Food Anim Pract 2009; 25(1): 195-208 https://doi.org/10.1016/j.cvfa.2008.10.004
  5. Flegel T, Henke D, Boettcher IC, Aupperle H, Oechtering G, Matiasek K. Magnetic resonance imaging findings in histologically confirmed Pug dog encephalitis. Vet Radiol Ultrasound 2009; 50(2): 241-242 https://doi.org/10.1111/j.1740-8261.2009.01527.x
  6. Green SL, Smith LL. Meningitis in neonatal calves: 32 cases (1983-1990). J Am Vet Med Assoc 1992; 201(1): 125-128
  7. Hong JM, Choi JY, Park HY, Huh K. Serial magnetic resonance imagings of multiple brain abscesses in a patient with pneumococcal meningoencephalitis. J Korean Med Sci 2008; 23(6): 1102-1104 https://doi.org/10.3346/jkms.2008.23.6.1102
  8. Jull BA, Merryman JI, Thomas WB, McArthur A. Necrotizing encephalitis in a Yorkshire terrier. J Am Vet Med Assoc 1997; 211: 1005-1007
  9. Lobetti RG, Pearson J. Magnetic resonance imaging in the diagnosis of focal granulomatous meningoencephalitis in two dogs. Vet Radiol Ultrasound 1996; 37: 424-427 https://doi.org/10.1111/j.1740-8261.1996.tb01254.x
  10. Mellema LM, Samii VF, Vernau KM, LeCouteur RA. Meningeal enhancement on magnetic resonance imaging in 15 dogs and 3 cats. Vet Radiol Ultrasound 2002; 43: 10-15 https://doi.org/10.1111/j.1740-8261.2002.tb00435.x
  11. Oliver JE Jr, Lorenz MD, Kornegay JN: Systemic or multifocal signs. In Handbook of veterinary neurology, 3^{rd} ed, Philadelphia: WB Saunders 1997; 345-353
  12. Radaelli ST, Platt SR. Bacterial meningoencephalomyelitis in dogs: a retrospective study of 23 cases (1990-1999). J Vet Intern Med 2002; 16: 159-163
  13. Schmidt MJ, Pilatus U, Wigger A, Kramer M, Oelschl\ddot{a}ger HA. Neuroanatomy of the calf brain as revealed by highresolution magnetic resonance imaging. J Morphol 2009; 270(6): 745-758 https://doi.org/10.1002/jmor.10717
  14. Seiler G, Cizinauskas S, Scheidegger J, Lang J. Low-field magnetic resonance imaging of a pyocephalus and as suspected brain abscess in a German shepherd dog. Vet Radiol Ultrasound 2001; 42: 417-422 https://doi.org/10.1111/j.1740-8261.2001.tb00962.x
  15. Seimiya Y, Ohshima K, Itoh H, Murakami R. Listeric septicemia with meningitis in a neonatal calf. J Vet Med Sci 1992; 54(6): 1205-1207 https://doi.org/10.1292/jvms.54.1205
  16. Seimiya YM, Murakami M, Takahashi M, Sasaki K, Miyazaki H, Kawashima K. A neonatal calf with concurrent meningoencephalitis by Enterobacter cloacae and enteritis by attaching and effacing Escherichia coli (O128). J Vet Med Sci 2007; 69(4): 445-448 https://doi.org/10.1292/jvms.69.445
  17. Seimiya YM, Takahashi M, Kudo T, Sasaki K. Meningoventriculitis caused by Streptococcus pluranimalium in a neonatal calf of premature birth. J Vet Med Sci 2007; 69(6): 657-660 https://doi.org/10.1292/jvms.69.657
  18. Tiches D, Vite CH, Dayrell-Hart B, Steinberg SA, Gross S, Lexa F. A case of canine central nervous system cryptococcosis: management with fluconazole. J Am Anim Hosp Assoc 1998; 34: 145-151
  19. Tipold A. Diagnosis of inflammatory and infectious diseases of the central nervous system in dogs: a retrospective study. J Vet Intern Med 1995; 9: 304-314 https://doi.org/10.1111/j.1939-1676.1995.tb01089.x
  20. von Praun F, Matiasek K, Grevel V, Alef M, Flegel T. Magnetic resonance imaging and pathologic findings associated with necrotizing encephalitis in two Yorkshire terriers. Vet Radiol Ultrasound 2006; 47(3): 260-264 https://doi.org/10.1111/j.1740-8261.2006.00137.x
  21. Zachary JF. Nervous System In: Pathologic Basis of Veterinary Disease 4^{th} Mosby: Elsevier 2007; 833-971