Prognosis of Malignant Melanoma on Lower Extremity

하지에 발생한 악성 흑색종의 예후

  • Kim, Ji Ye (Institute for Human Tissue Restoration Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Lee, Won Jai (Institute for Human Tissue Restoration Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Lew, Dae Hyun (Institute for Human Tissue Restoration Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Rah, Dong Kyun (Institute for Human Tissue Restoration Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine) ;
  • Tark, Kwan Chul (Institute for Human Tissue Restoration Department of Plastic and Reconstructive Surgery, Yonsei University College of Medicine)
  • 김지예 (연세대학교 의과대학 성형외과학교실 인체조직복원 연구소) ;
  • 이원재 (연세대학교 의과대학 성형외과학교실 인체조직복원 연구소) ;
  • 유대현 (연세대학교 의과대학 성형외과학교실 인체조직복원 연구소) ;
  • 나동균 (연세대학교 의과대학 성형외과학교실 인체조직복원 연구소) ;
  • 탁관철 (연세대학교 의과대학 성형외과학교실 인체조직복원 연구소)
  • Published : 2009.07.15

Abstract

Purpose: Malignant melanoma is recognized as the most serious skin cancer. We examined anatomical distribution and 5 - year survival rate of each stage of malignant melanoma on lower leg. Methods: We retrospectively analyzed the medical records of 91 patients(46 males and 45 females) with malignant melanoma on lower leg from 1985 to 2008. Age, sex, anatomical distribution and 5 - year survival rates of each stage of malignant melanoma on lower leg were investigated. Also, 5 - year survival rates of each stage and invasion depth of malignant melanoma on heel pad were investigated. Results: On lower leg, most frequently 32 cases(35.1%) occurred on heel pad, 27 cases(29.7%) occurred on dorsum of foot, 18 cases(19.8%) in toe and 14 cases(15.4%) on others in lower leg. We used the excision margin as 3 ~ 5 cm. After wide excision, in stage III, IV, the patients underwent the immunologic / chemo - therapy. The incidences of each stage were 22 cases(24.2%) in stage I, 47(51.6%) in II, 17(18.7%) in III and 5(5.5%) in IV. The 5 - year survival rates of each stage were 85%, 53.2%, 47.1% and 40%. On heel pad, the incidences of each stage were 5 cases(15.6%) in stage I, 19 cases(59.4%) in II, 7 cases(21.9%) in III and 1 case(3.1%) in IV. The 5 - year survival rates of each stage were 80%, 63.2%, 42.9% and 100%. On heel pad, incidence of local recurrence was 2 and 5 - year survival rate of this case was 100%. And systemic recurrence was 9 and 5 - year survival rate of this case was 55.6%. Conclusion: The 5 - year survival rate of malignant melanoma on heel pad was higher than previous study. To maintain the weight - bearing function of foot, we recommend the active reconstructive surgery for heel pad reconstruction after wide excision of heel pad malignant melanoma.

Keywords

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