Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
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Relationship between the depth of cingulate sulcus on neonatal high resolution cranial ultrasound and gestational age

신생아 고해상 뇌 초음파검사에서 대상고랑의 깊이와 재태기간과의 관계

  • Choi, Young Chil (Department of Radiology, Konkuk University School of Medicine) ;
  • Choi, Jin Yong (Department of Neurology, Konkuk University School of Medicine) ;
  • Lee, Jung Hwa (Department of Pediatrics, Konkuk University School of Medicine)
  • 최영칠 (건국대학교 의학전문대학원 영상의학교실) ;
  • 최진영 (건국대학교 의학전문대학원 신경과학교실) ;
  • 이정화 (건국대학교 의학전문대학원 소아과학교실)
  • Received : 2009.06.29
  • Accepted : 2009.09.11
  • Published : 2009.10.15
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Abstract

Purpose:It is critical that the exact gestational age of a newborn baby, especially premature baby, be determined to evaluate the status of a disease and its management and to estimate the prognosis of a patient. This study aimed to investigate an easy and accurate method to estimate gestational age on cranial ultrasound, requiring minimal additional time and equipment. Methods:A high-resolution coronal sonographic image was obtained via the anterior fontanel with a 5-12 Mhz linear probe after the usual cranial sonographic examination. We measured the depth of cerebral hemisphere, thickness of corpus callosum, and depth of cingulate sulcus and obtained the correlations between these factors and gestational age. Results:Depth of cingulate sulcus had the highest correlation coefficiency with gestational age (r=0.878, P=0.000). All the cases, except for 2 cases, had a gestational age of more than 37 weeks, when the depths of cingulate sulcus were more than 0.55 cm, and had a gestational age less than 34 weeks, when the depths of cingulate sulcus were less than 0.35 cm. Conclusion:Measurement of the depth of cingulate sulcus was a simple and accurate method to estimate the gestational age on cranial ultrasound. The gestational age is more than 37 weeks, when the depth of cingulate sulcus is more than 0.55 cm, and is less than 34 weeks, when the depth of cingulate sulcus is less than 0.35 cm.

목 적:신생아, 특히 미숙아에서 재태기간의 정확한 측정은 환자의 상태와 질병을 이해하여 치료하고 예후를 예상하는데 필수적이다. 이에 저자들은 신생아 뇌 초음파 검사시 최소한의 시간과 기구의 추가 사용으로 간편하게 정확한 재태기간을 추정할 수 있는 방법을 연구하였다. 방 법:일반적인 뇌 초음파 검사를 시행한 후 5-12 Mhz의 고해상도 선형 탐촉자를 사용하여 대천문을 통하여 관상면의 영상을 얻었고 여기에서 대뇌반구의 깊이와 뇌량의 두께 및 대상고랑의 깊이를 측정하여 재태기간과의 상관관계을 구하였다. 결 과:대뇌반구의 깊이, 뇌량의 두께 및 대상고랑의 깊이 중 재태기간과 가장 상관관계가 높은 측정치는 대상고랑의 깊이로 Pearson 상관계수 0.878을 보였다(P=0.000). 또한 대상고랑의 깊이가 0.55 cm 이상인 경우 단 두 례를 제외하고 모두 재태기간이 37주 이상이었고 대상고랑의 깊이가 0.35 cm 미만인 경우는 모두 34주 미만이었다. 결 론:고해상도 뇌 초음파 검사를 통해 측정된 대상고랑의 깊이는 신생아의 정확한 재태기간 측정에 유용하게 이용될 수 있다. 그러나 보다 더 많은 수의 신생아를 대상으로 한 대규모 연구가 필요할 것으로 생각된다.

Keywords

Acknowledgement

Supported by : 건국대학교

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