Analytical Science and Technology (분석과학)
- Volume 22 Issue 5
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- Pages.407-414
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- 2009
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- 1225-0163(pISSN)
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- 2288-8985(eISSN)
DOI QR Code
Simultaneous quantitative determination of urinary cholesterol, desmosterol and lanosterol in pravastatin treated rats by gas chromatography/mass spectrometry
Gas Chromatography/Mass Spectrometry를 이용한 Pravastatin 투여 쥐의 뇨 중 Cholesterol, Desmosterol, Lanosterol의 동시분석법
- Kumar, Bhowmik Salil (Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology) ;
- Chung, Bong Chul (Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology) ;
- Lee, Young-Joo (College of Pharmacy, Kyung Hee University) ;
- Yi, Hong Jae (College of Pharmacy, Kyung Hee University) ;
- Jung, Byung Hwa (Bioanalysis and Biotransformation Research Center, Korea Institute of Science and Technology)
- 사릴 꾸마르 (한국과학기술연구원 생체대사연구센터) ;
- 정봉철 (한국과학기술연구원 생체대사연구센터) ;
- 이영주 (경희대학교 약학대학) ;
- 이홍재 (경희대학교 약학대학) ;
- 정병화 (한국과학기술연구원 생체대사연구센터)
- Received : 2009.07.09
- Accepted : 2009.08.31
- Published : 2009.10.25
Abstract
A simultaneous determination method for cholesterol, lanosterol and desmosterol was developed using gas chromatography/mass spectrometry. Urine was enzymatically hydrolyzed with
가스크로마토그래피-질량분석기 (GC/MS)를 이용하여 뇨 중의 cholesterol, lanosterol, desmosterol 의 동시분석법을 개발하였다. 뇨 시료는