Consideration on Flap Surgery in Vegetative Patients Having Nosocomial Infection

병원 감염 창상을 가진 식물 인간 상태에서의 피판술시 고려사항

  • Kim, Jeong Tae (Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University) ;
  • Kim, Kee Woong (Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University) ;
  • Kim, Yeon Hwan (Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University) ;
  • Kim, Chang Yeon (Department of Plastic and Reconstructive Surgery, College of Medicine, Hanyang University)
  • 김정태 (한양대학교 의과대학 성형외과학 교실) ;
  • 김기웅 (한양대학교 의과대학 성형외과학 교실) ;
  • 김연환 (한양대학교 의과대학 성형외과학 교실) ;
  • 김창연 (한양대학교 의과대학 성형외과학 교실)
  • Published : 2009.05.15

Abstract

Purpose: The vegetative state is a clinical condition with complete unawareness of self and environment, but with preservation of brain - stem functions. Vegetative patients may have nosocomial infections in their wounds, like pressure sores and infected craniums after cranioplasties. Usually flap surgery is necessary for those wounds, but decision of undergoing surgery is difficult because of various adverse conditions of vegetative patients. We share our experience of several successful flap surgeries in vegetative patients, and evaluate obstacles and requirements to get satisfactory results. Methods: From December 2005 to September 2008, a total of 4 vegetative patients underwent surgeries. In 2 patients with infected artificial craniums, scalp reconstructions with free flaps were performed. In other 2 patients with huge pressure sores with sepsis, island flap coverage of wounds was done. Retrospective study was done on hospital day, vegetative period, number of surgeries done, underlying diseases, causative bacteria, and contents of informed consent. Results: Mean hospital day was 14 months and mean vegetative period was 17.5 months. Patients underwent average of 4.5 surgeries under general anesthesia. There were several underlying diseases like hypertension, DM, CHF and chronic anemia. MRSA(Methicilin - resistant Staphylococcus Aureus) was cultured from every patient's wounds. Informed consent included a warning for high mortality and a need of attentive familial cooperation. Conclusion: There are three requirements for doing flap surgeries in vegetative patients. First, to prevent aggravation of brain damage and underlying diseases by general anesthesia, multidisciplinary team approach is needed. Second, operation should be beneficial for prolonging patient's lifespan. Third, because postoperative care is very difficult and long hospitalization is needed, detailed informed consent and highly cooperative attitude of family should be confirmed before operation.

Keywords

References

  1. The Multi-Society Task Force on PVS: Medical aspects of the persistent vegetative state(first of two parts). N Engl J Med 330: 1499, 1994 https://doi.org/10.1056/NEJM199405263302107
  2. William WC: Dejong's neurologic examination. 6th ed, Philladelphia, Lippincott Williams & Wilkins, 2005, p613
  3. Arenella C: Coma and persistent vegetative state: an exploration of terms. Okla Nurse 51: 14, 2006
  4. Freeman EA: Protocols for vegetative patients. Med J Aust 159: 428, 1993
  5. Jennett B: The vegetative state. J Neurol Neurosurg Psychiatry 73: 355, 2002 https://doi.org/10.1136/jnnp.73.4.355
  6. Tresch DD, Sims FH, Duthie EH, Goldstein MD, Lane PS: Clinical characteristics of patients in the persistent vegetative state. Arch Intern Med 151: 930, 1991 https://doi.org/10.1001/archinte.151.5.930
  7. Hagisawa S, Barbenel J: The limits of pressure sore prevention. J R Soc Med 92: 576, 1999 https://doi.org/10.1177/014107689909201109
  8. Moreira-Gonzalez A, Jackson IT, Miyawaki T, Barakat K, DiNick V: Clinical outcome in cranioplasty: critical review in long-term follow-up. J Craniofac Surg 14: 144, 2003 https://doi.org/10.1097/00001665-200303000-00003
  9. Cheng YK, Weng HH, Yang JT, Lee MH, Yang TC, Chang CN: Factors affecting graft infection after cranioplasty. J Clin Neurosci 15: 1115, 2008 https://doi.org/10.1016/j.jocn.2007.09.022
  10. Robert KS, Stephen FD: Anesthesia and co-existing disease. 4th ed, London, Churchill Livingstone, 2002, p248
  11. Lee F: Anesthesia and uncommon disease. 5th ed, Philladelphia, Saunders, 2005, p515
  12. The Multi-Society Task Force on PVS: Medical aspects of the persistent vegetative state(second of two parts). N Engl J Med 330: 1572, 1994 https://doi.org/10.1056/NEJM199406023302206