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Guidelines for childhood urinary tract infection

소아 요로감염의 임상 지침

  • Lee, Seung Joo (Department of Pediatrics, Ewha Womans University School of Medicine)
  • 이승주 (이화여자대학교 의학전문대학원 소아과학교실)
  • Received : 2009.09.02
  • Accepted : 2009.09.04
  • Published : 2009.09.15

Abstract

Urinary tract infection (UTI), the most common bacterial disease in childhood, is frequently associated with urinary tract anomalies (15-50%) and can induce renal scarring, which is a cause of hypertension and chronic kidney disease. Despite the high risk of renal scarring in infancy, the diagnosis may be delayed due to its nonspecific presenting symptoms; moreover, over-diagnosis is frequent due to the contamination of urine samples. The delay in diagnosis and treatment may induce sepsis or renal scar, while over-diagnosis is responsible for unnecessary antibiotic treatment and costly urinary imaging studies. UTI guidelines have been ever-changing for the past three decades, but some controversial issues remain. This article is a revision of the previous KSPN (Korean Society of Pediatric Nephrology) guideline and addresses the recent controversies concerning childhood UTI.

Keywords

References

  1. Aggarwal VK, Verrier JK, Asscher AW, Evans C, William LA. Covert bacteriuria: Longterm follow-up. Arch Dis Child 1991;66:1284-6 https://doi.org/10.1136/adc.66.11.1284
  2. American Academy of Pediatrics. Practice parameter: The diagnosis, treatment and evaluation of the initial urinary tract infection in febrile infants and young children. Pediatrics 1999;103:843-52
  3. Costers M, Damme-Lombaerts RV, Levtchenko E, Bogaert G. Antibiotic prophylaxis for children with primary vesicoureteral reflux: Where do we stand today? Advance in Urol;doi: 10.1155/2008/217805
  4. Craig JC, Wheeler DM, Irwig L, Howman-Giles RB. How accurate is dimercaptosuccinic acid scintigraphy for the diagnosis of acute pyelonephritis? A meta-analysis of experimental studies. J Nuclear Med 2000;41:986-93
  5. Behrman RE, Kliegman RM, Jenson HB. Nelson Textbook of Pediatrics, 18th ed. WB Saunders co., Piladelphia 2007; 2223-8
  6. Elder JS, Peters CA, Arant Jr BS. Pediatric vesicoureteral reflux guidelines panel summary report on the management of primary vesicoureteral reflux in children. J Urol 1997;157: 1846-51 https://doi.org/10.1016/S0022-5347(01)64882-1
  7. Gorelick MH, Shaw KN. Clinical decision rule to identify febrile young girls at risk for urinary tract infection. Arch Pediatr Adolesc Med 2000;154:386-90 https://doi.org/10.1001/archpedi.154.4.386
  8. Avner ED, HarmonWE, Niadaut P. Pediatric Nephrology, 5th ed., Lippincott Williams & Wilkins, 2004:1007-25
  9. Hiraoka M, Hashimoto G, Tsuchida S, Tsukahara H, Ohshima Y, Mayumi M, Early treatment of urinary tract infection prevents renal damage on cortical scintigraphy. Pediatr Nephrol 2003;18:115-8 https://doi.org/10.1007/s00467-002-1023-y
  10. Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER. Imaging studies after a first febrile urinary tract infection in young children. New Engl J Med 2003; 348:195-202 https://doi.org/10.1056/NEJMoa021698
  11. Jacobson B, Esbjorner E, Hansson S, Swedish Pediatric Nephrology Association. Minimum incidence and diagnostic rate of first urinary tract infection. Pediatrics 1999;104:222-6 https://doi.org/10.1542/peds.104.2.222
  12. Jodal U. Suprapubic aspiration of urine in the diagnosis of urinary tract infection in infants. Acta Pediatr 2002;91:497- 8 https://doi.org/10.1080/080352502753711551
  13. Jodal U, Lindberg U. Guidelines for management of children with urinary tract infection and vesicoureteral reflux. Recommendation from a Swedish state-of-the-art conference. Acta Pediatr Suppl 1999;431:87-9
  14. Keren R, Chan E. A meta-analysis of randomized controlled trials comparing short- and long-course therapy for urinary tract infection in young children Pediatrics.2002;109:e70 https://doi.org/10.1542/peds.109.5.e70
  15. Kontiokari T, Nuutinen M, Uhari M. Dietary factors affecting usceptibility to urinary tract infection. Pediatr Nephrol 2004; 19:378-83 https://doi.org/10.1007/s00467-003-1410-z
  16. Levtchenko E, Lahy C, Levy J, Ham H, Piepsz A. Treatment of children with acute pyelonephritis: A prospective randomized study. Pediatr Nephrol 2001;16:878-82 https://doi.org/10.1007/s004670100690
  17. Lee JW, Cho SJ, Park EA, Lee SJ. Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants. Pediatr Nephrol 2006;21:1127-30 https://doi.org/10.1007/s00467-006-0104-8
  18. Lee SJ, Shim YH, Cho SJ, Lee JW. Probiotic prophylaxis in children with persistent primary vesicoureteral reflux. Pediatr Nephrol 2007;22:1315-20 https://doi.org/10.1007/s00467-007-0507-1
  19. Liaw LCT. Home collection of urine for culture from infants by three methods: Survey of parents and bacterial contamination rates. Br Med J 2000;320:1312-7 https://doi.org/10.1136/bmj.320.7245.1312
  20. Linshaw MA. Controversies in childhood urinary tract infections. World J Urol 1999;17:383-95 https://doi.org/10.1007/s003450050164
  21. Marild S, Hansson S, Jodal U, Oden A, Svedberg K. Protective effect of breast feeding against urinary tract infection. Acta Pediatr 2004;93:164-8 https://doi.org/10.1080/08035250310007402
  22. Michael M, Hodson EM, Craig JC, Moyer VA. Short compared with standard duration of antibiotic treatment for urinary tract infection: A systematic review of randomized controlled trials. Arch Dis Child 2002;87:118-23 https://doi.org/10.1136/adc.87.2.118
  23. Miller T, Philips S Pyelonephritis: The relationship between infection, renal scarring and antimicrobial therapy. Kidney Int 1981;19:654-62 https://doi.org/10.1038/ki.1981.65
  24. Mori R, Lakhanpaul M, Verrier-Jones, K. 'Diagnosis and management of urinary tract infection in children: summary of NICE guidance, Br Med J 2007;335:395-7 https://doi.org/10.1136/bmj.39286.700891.AD
  25. Natioanl Institute for Health and Clinical Exellence, "Urinary tract infection in children," NICE, London, UK, 2007, http: //guidance.nice.org.uk/CG54
  26. Saux NL, Pham B, Moher D. Evaluating the benefits of antimicrobial prophylaxis to prevent urinary tract infections in children: a systemic review. Can Med Ass J 2000;163: 523-9
  27. Shaw KN, Gorelick M, McGowen KL, Myakscoe NM, Schwartz JS. Prevalence of urinary tract infection in febrile young children in the emergency department. Pediatrics 1998; 102:1-5 https://doi.org/10.1542/peds.102.1.1
  28. Thompson RH, Chen JJ, Pugach J, Naseer S. Cessation of prophylactic antibiotics for managing persistent vesicoureteral reflux. J Urol 2001;166:1465-9 https://doi.org/10.1016/S0022-5347(05)65811-9
  29. William AA. Changing concepts in the management of pediatric urinary tract infection. Pediatr Ann 1999;28:631-4 https://doi.org/10.3928/0090-4481-19991001-04
  30. Williams GJ, Lee A, Craig JC, Antibiotics for the prevention of urinary tract infection in children: A systemic review of randomized controlled trials. J Pediatr 2001;138:868-74 https://doi.org/10.1067/mpd.2001.113785
  31. Wiswell TE, Roscelli JD. Corroborative evidence for the decreased incidence of urinary tract infection in circumcised male infants. Pediatrics 1986;78:96-9

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