DOI QR코드

DOI QR Code

Neonatal seizures in Korea, 1983-2009

국내 신생아 경련에 대한 보고

  • Suh, Eun Sook (Department of Pediatrics, College of Medicine, Soonchunhyang University)
  • 서은숙 (순천향대학교 의과대학 소아과학교실)
  • Received : 2009.06.22
  • Accepted : 2009.08.22
  • Published : 2009.09.15

Abstract

Neonatal seizures are the most common and distinctive clinical sign of prenatal and/or neonatal brain disorders. Newborn infants with seizures are at risk of mortality and survivors at risk for neurologic impairment, developmental delay, and subsequent epilepsy. Fifteen reports on neonatal seizures in Korea from 1983 to 2009 were analyzed. A total of 731 neonatal seizure cases were reported. Day of seizure onset, etiology, type of seizures, electroencephalogram findings, and outcomes were analyzed. It is necessary to establish a basic report for a future nationwide study of neonatal seizures.

Keywords

References

  1. Volpe JJ. Neonatal seizures. Neurology of the Newborn. 5th ed. Philadelphia: WB Saunders Co. 2008:203-44
  2. Scher MS, Aso K, Berggarly ME, Steppe DA, Painter MJ. Electrographic seizures in preterm and full-term neonates: clinical correlates, associated brain lesions, and risk for neurological sequelae. Pediatrics 1993;91:128-34
  3. Bey AM, Cunnungham CA, Chee KY, Flanagan D. Outcome of neonate with electrographically identified seizures, or at risk of seizures. Pediatr Neurol 1997;16:225-31 https://doi.org/10.1016/S0887-8994(97)00019-2
  4. Legido A, Clancy RR, Berman PH. Neurologicl outcome after electrographically proven neonatal seizures. Pediatrics 1991; 88:583-96
  5. Tekgul H, Gauvreau K, Soul J, Murphy L, Robertson R, Stewart J, et al. The current etiological profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 2006;117:1270-80 https://doi.org/10.1542/peds.2005-1178
  6. Saliba RM, Anneger JF, Waller DK, Tyson JE, Mizrahi EM. Incidence of neonatal seizures in Harris County, Texas, 1992-1994. Am J Epidemiol 1999;150:763-9
  7. Ronen GM, Penny S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: A population- based study. J Pediatr 1999;134:71-5 https://doi.org/10.1016/S0022-3476(99)70374-4
  8. Lanska MJ, Lanska DJ, Baumann RJ, Kryscio R. A population-based study of neonatal seizures in Fayette County, Kentucky. Neurology 1995;45:724-32
  9. Lanska MJ, Lanska DJ. Neonatal seizures in the United States. Result of the National Hospital Discharge Survey. 1980-1991. Neuroepidemiology 1996;15:117-25 https://doi.org/10.1159/000109898
  10. Volpe JJ. Neonatal seizures: Current concepts and revised classification. Pediatrics 1989;84:422-28
  11. Kim MJ, Lee SJ, Lee K. A clinical study of neonatal convulsion. J Korean Pediatr Soc 1983;26:10-6
  12. Park CY, Yum MK, Choi JH, Hwang YS, Yun CK. A clinical study on neonatal seizures. J Korean Pediatr Soc 1985;28:29-39
  13. Kim SC, Jeon JS, Bae CW, Chung SJ, Ahn CI. Clinical observation and electroencephalographic Findings relate to prognostic factor in Neonatal Seizure. J Korean Pediatr Soc. 1989 Jun;32:816-22
  14. Kong BS, Lee RS, Park SK, Park HJ. A clinical study on neonatal seizures. J Korean Pediatr Soc 1991;34:230-9
  15. Song MS, Kang YJ, Park IS, Choi HJ, Kim SJ. Correlation of neurologic outcome with neonatal seizure associated clinical correlators. J Korean Child Neurol Soc 1994;2:59-71
  16. Park W, Kim DY, Jung CZ, Kim SD. Clincal study of neonatal seizures. J Korean Child Neurol Soc 1998;6:71-82
  17. Oh KS. Clinical study and prognostic factors of neonatal seizures. J Wonkwang Med Sci 1998;14:257-67
  18. Kim SK, Lee R, Lee IK, Kim KJ, Hwang YS. Factors related to the outcome of neonatal seizures. J Korean Pediatr Soc 2000;43:267-73
  19. Kim CW, Jang CH, Kim HM, Choe BH, Kwon SH. Clinical characteristics and prognosis of neonatal seizures. J Korean Pediatr Soc 2003;46:1253-9
  20. Jung KH, Kim YH, Kwon YS, Jun YH, Kim SK, Son BK. Clinical characteristics of neonatal status epilepticus. Korean J Pediatr 2005;48:1342-7
  21. Jeoung MS, Chun JM, Kim KA, Ko SY, Lee YK, Han BH, et al. Clinical study of perinatal infarcts. Korean J Perinatol 2005;16:154-62
  22. Shin MS, Chang MY, Lee KS. A scoring system to predict the outcomes in neonatal seizures. J Korean Child Neurol Soc 2006;14:68-78
  23. Yeo CY, Kim DK, Kim SH, Song ES, Woo YJ, Choi YY. Predicting factors for neurological outcome in full-term neonates with hypoxic-ischemic encephalopathy. J Korean Soc Neonatol 2006;13:226-32
  24. Min TK, Lee WR, Suh ES. Risk factors of perinatal asphyxia related to whether to survive. J Soonchunhyang Med Coll 2007;13:207-18
  25. Kim MY, Suh ES. Clinical characteristics with risk factors for term neonatal seizures. J Korean Child Neurol Soc 2009;17: 22-32
  26. Holms GL, Lombroso CT. Prognostic value of background patterns in the neonatal EEG. J Clin Neurophysiol 1993;10: 323-52 https://doi.org/10.1097/00004691-199307000-00008
  27. Dennis J. The implications of neonatal seizures. Adv Perinatal Neurol 1979;1:205-24
  28. Mellitis ED, Holden KR, Freeman JM. Neonatal seizures, II A multivariate analysis of factors associated with outcomes. Pediatrics 1982;70:177-85
  29. Thibeault-Eybalin MP, Lortie A, Carmant L. Neonatal seizures: do they damage the brain? Pediatr Neurol 2009;40: 175-80 https://doi.org/10.1016/j.pediatrneurol.2008.10.026
  30. Holden KR, Mellitis ED, Freeman JM. Neonatal seizure correlation of prenatal and perinatal events with the outcome. Pediatrics 1982;70:166-76
  31. Legido A, Clancy RR, Berman PH. Neurologic outcome after electroencephalographically proven neonatal seizures. Pediatrics 1991;88:583-96
  32. Holanda M, de Malo AN. Comparative clinical study of preterm and fullterm newborn neonatal seizures. Arq Neuropsiquiatri 2006;64:45-50 https://doi.org/10.1590/S0004-282X2006000100010
  33. Clancy RR, Legido A. Postnatal epilepsy after EEG-confirmed neonatal seizure. Epilepsia 1991;32:69-76 https://doi.org/10.1111/j.1528-1157.1991.tb05614.x
  34. Patrizi S, Holmes G, Orzalesi M, Allemand F. Neonatal seizure: chracteristics of EEG ictal activity in preterm and full term infants. Brain Dev 2003;25:427-37 https://doi.org/10.1016/S0387-7604(03)00031-7
  35. Bruquell PJ, Glennon CM, DiMario FJ. Lerer T, Eisenfeld L. Prediction of outcome based on clinical seizure type in newborn infants. J Pediatr 2002;140:707-12 https://doi.org/10.1067/mpd.2002.124773
  36. Pisani F, Barilli AL, Sisti L, Bevilacqua G, Seri S. Preterm infant with video-EEG confirmed seizures: outcome at 30 months of age. Brain Dev 2008;30:20-30 https://doi.org/10.1016/j.braindev.2007.05.003
  37. Ronen GM, Buckley D, Penny S, Streiner DL. Long-term prognosis in children with neonatal seizures: a population- based study. Neurology 2007;69:1816-22 https://doi.org/10.1212/01.wnl.0000279335.85797.2c
  38. Holden KR, Mellitis ED, Freeman JM. Neonatal seizures I. Correlation of prenatal events with outcomes. Pediatrics 1982;70:165-76
  39. Ellison PH, Largent JA, Bahr JP. A scoring system to predict outcome following neonatal seizures. J Pediatr 1981;99:455- 9 https://doi.org/10.1016/S0022-3476(81)80348-4

Cited by

  1. Follow-up of Full-term Neonatal Seizures: Prognostic Factors for Neurodevelopmental Sequelae vol.20, pp.1, 2013, https://doi.org/10.5385/nm.2013.20.1.97
  2. Seizure Scoring System and Neurodevelopmental Outcomes in Very Low Birth Weight Infants with Neonatal Seizures vol.20, pp.4, 2009, https://doi.org/10.5385/nm.2013.20.4.428