참고문헌
- Cooper DA, Eldridge AL, Peters JC. Dietary carotenoids and lung cancer: A review of recent research. Nutr. Rev. 57: 133-145 (1999) https://doi.org/10.1111/j.1753-4887.1999.tb01794.x
- Cooper DA, Eldridge AL, Peters JC. Dietary carotenoids and certain cancers, heart disease, and age related macular degeneration: A review of recent research. Nutr. Rev. 57: 201-214 (1999) https://doi.org/10.1111/j.1753-4887.1999.tb06944.x
- Willett WC. Diet and cancer: One view at the start of the millennium. Cancer Epidem. Biomark. 10: 3-8 (2001)
- Riboli E, Norat T. Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. Am. J. Clin. Nutr. 78: 559S-569S (2003) https://doi.org/10.1093/ajcn/78.3.559S
- Edge R, McGarvey DJ, Truscott TG. The carotenoids as antioxidants-a review. J. Photochem. Photobiol. B 41: 189-200 (1997) https://doi.org/10.1016/S1011-1344(97)00092-4
- Giovannucci E. Tomatoes, tomato-based products, Iycopene, and cancer: Review of the epidemiologic literature. J. Natl. Cancer I. 91:317-331 (1999) https://doi.org/10.1093/jnci/91.4.317
- Hadley CW, Miller EC, Schwartz SJ, Clinton SK. Tomatoes, lycopene, and prostate cancer: Progress and promise. Exp. BioI. Med. 227: 869-880 (2002) https://doi.org/10.1177/153537020222701006
- Tapiero H, Townsend DM, Tew KD. The role of carotenoids in the prevention of human pathologies. Biomed. Pharmacother. 58: 100-110 (2004) https://doi.org/10.1016/j.biopha.2003.12.006
- Chew BP, Park JS. Carotenoid action on the immune response. J. Nutr. 134: 257S-261S (2004) https://doi.org/10.1093/jn/134.1.257S
- Palermo JA, Gros EG, Seldes AM. Carotenoids from three red algae of the Corallinaceae. Phytochemistry 30: 2983-2986 (1991) https://doi.org/10.1016/S0031-9422(00)98236-0
- Dembitsky VM, Maoka T. Allenic and cumulenic lipids. Prog. Lipid Res. 46: 328-375 (2007) https://doi.org/10.1016/j.plipres.2007.07.001
- Mori K, Ooi T, Hiraoka M, Oka N, Hamada H, Tamura M, Kusumi T. Fucoxanthin and its metabolites in edible brown algae cultivated in deep seawater. Mar. Drugs 2: 63-72 (2004) https://doi.org/10.3390/md202063
- Matsuno T. Aquatic animal carotenoids. Fisheries Sci. 67: 771-783 (2001) https://doi.org/10.1046/j.1444-2906.2001.00323.x
- Goodwin TW. Metabolism, nutrition, and function of carotenoids. Ann. Rev. Nutr. 6: 273-297 (1986) https://doi.org/10.1146/annurev.nu.06.070186.001421
- Matsuno T, Nagata S, Kitamura K. New carotenoids, parasiloxanthin, and 7,8-dihydroparaciloxanthin. Tetrahedron Lett. 50: 4601-4604 (1976) https://doi.org/10.1016/S0040-4039(00)93942-X
- Yamashita E, Arai S, Matsuno T. Metabolism of xanthophylls to vitamin A and new apocarotenoids in liver and skin of black bass, Micropterus salmoides. Comp. Biochem. Physiol. 113B: 485-489 (1996) https://doi.org/10.1016/0305-0491(95)02069-1
- Matsuno T, Tsushima M, Maoka T. Salmoxanthin, deepoxysalrnoxanthin, and 7,8-didehydrooeepoxysalmoxanthin from the salmon Oncorhynchus keta. J. Nat. Prod. 64: 507-510 (2001) https://doi.org/10.1021/np0004294
- Davies BH. Carotenoid metabolism in animals: A biochemist's view. Pure. Appl. Chem. 57: 679-684 (1985) https://doi.org/10.1351/pac198557050679
- Sachindra NM, Bhaskar N, Mahendrakar NS. Carotenoids in different body components of Indian shrimps. J. Sci. Food Agr. 85:167-172 (2005) https://doi.org/10.1002/jsfa.1977
- Renstrom B, Borch G, Liaaen-Jensen S. Natural occurrence of enantiomeric and meso-astaxanthin 4. Ex Shrimp (Pandalus borealis). Compo Biochem. Physiol. 69B: 621-624 (1981) https://doi.org/10.1016/0305-0491(81)90359-X
- Negre-Sadargues G, Castillo R, Seginzac M. Carotenoid pigments and tropic behavior of deep-sea shrimps (Crustacea, Decapoda, Alvinocarididae) from a hydrothermal area of the Mid-Atlantic Ridge. Compo Biochem. Physiol. 127A: 293-300 (2000) https://doi.org/10.1016/S1095-6433(00)00258-0
- Milicua JCG, Garate AM, Barbon PG, Gomez R. Borohydride reduction of the blue carotenoid-protein complex from Procambarus clarki. Compo Biochem. Physiol. 95B: 119-123 (1990) https://doi.org/10.1016/0305-0491(90)90257-T
- Hussein G, Sankawa U, Goto H, Matsumoto K, Watanabe H. Astaxanthin, a carotenoid with potential in human health and nutrition. J. Nat. Prod. 69: 443-449 (2006) https://doi.org/10.1021/np050354+
- Khare A, Moss GP, Weedon BCL. Mytiloxanthin and isomytiloxanthin, two novel acetylenic carotenoids. Tetrahedron Lett. 40: 3921-3924 (1973) https://doi.org/10.1016/S0040-4039(01)87073-8
- Maoka T, Matsuno T. Isolation and structural elucidation of three new acetylenic carotenoids from the Japanese sea mussel Mytilus coruscus. B. Jpn. Soc. Sci. Fish. 54: 1443-1447 (1988) https://doi.org/10.2331/suisan.54.1443
- Maoka T, Tsushima M, Matsuno T. New acetylenic carotenoids from the starfishes Asterina pectinifera and Asterias amurensis. Comp. Biochem. Physiol. 93B: 829-834 (1989) https://doi.org/10.1016/0305-0491(89)90054-0
- Matsuno T, Sakaguchi S. A novel marine carotenoid, mactraxanthin from the Japanese edible surf clam. Tetrahedron Lett. 24: 911-912 (1983) https://doi.org/10.1016/S0040-4039(00)81562-2
- Matsuno T, Sakaguchi S, Ookubo M, Maoka T. Isolation and identification of amaroucisxanthin A from the bivalve Paphia euglypta (sudaregai in Japanese). B. Jpn. Soc. Sci. Fish. 51: 1909 (1985) https://doi.org/10.2331/suisan.51.1909
- Matsuno T, Maoka T, Shiba K, Ookubo M. Isolation of fucoxanthinol from short-necked clam Tapes philippinarum (asari in Japanese). B. Jpn. Soc. Sci. Fish. 52: 167 (1986) https://doi.org/10.2331/suisan.52.167
- Matsuno T, Ookubo M, Komori T. Carotenoids oftunicates. III. The structural elucidation of two new marine carotenoids, amarouciaxanthin A and B. J. Nat. Prod. 48: 606-613 (1985) https://doi.org/10.1021/np50040a015
- Ookubo M, Matsuno T. Carotenoids of sea squirts II. Comparative biochemical studies of carotenoids in sea squirts. Comp. Biochem. Physiol. 81B: 137-141 (1985) https://doi.org/10.1016/0305-0491(85)90174-9
- Fujiwara Y, Maoka T, Ookubo M, Matsuno T. Crassostreaxanthin A and B: Novel marine carotenoids from the oyster Crassostrea gigas. Tetrahedron Lett. 33 4941-4944 (1992) https://doi.org/10.1016/S0040-4039(00)61240-6
-
Tsushima M, Matsuno T. Occurrence of 9'Z-
$\beta$ -echinenone in the sea urchin Pseudocentrotus depressus. Compo Biochem. Physiol. 118B: 921-925 (1997) https://doi.org/10.1016/S0305-0491(97)00302-7 - Tsushima M, Fujiwara Y, Matsuno T. Novel marine di-Zcarotenoids:Cucumariaxanthins A, B, and C from the sea cucumber Cucumaria japonica. J. Nat. Prod. 59: 30-34 (1996) https://doi.org/10.1021/np960022s
-
Rousseau EJ, Davison AJ, Dunn B. Protection by
$\beta$ -carotene and related compounds against oxygen-mediated cytotoxicity and genotoxicity: Implications for carcinogenesis and anticarcinogenesis. Free Radical Bio. Med. 13: 407-433 (1992) https://doi.org/10.1016/0891-5849(92)90183-H - Hirayama O, Nakamura K, Hamada S, Kobayasi Y. Singlet oxygen quenching ability of naturally occurring carotenoids. Lipids 29: 149-150 (1994) https://doi.org/10.1007/BF02537155
- Mortensen A, Skibsted LH, Truscott TG. The interaction of dietary carotenoids with radical species. Arch. Biochem. Biophys. 385: 13-19 (2001) https://doi.org/10.1006/abbi.2000.2172
- Chew BP, Park JS. Carotenoid action on the immune response. J. Nutr. 134: 257S-261S (2004) https://doi.org/10.1093/jn/134.1.257S
- Jackson H, Braun CL, Ernst H. The chemistry of novel xanthophyll carotenoids. Am. J. Cardiol. 101: 50D-57D (2008) https://doi.org/10.1016/j.amjcard.2008.02.008
- Di Mascio P, Murhy ME, Sies H. Antioxidant defense systems: The role of carotenoids, tocopherols, and thiols. Am. J. Clin. Nutr. 53:194S-200S (1991) https://doi.org/10.1093/ajcn/53.1.194S
-
Fukuzawa K, Inokami Y, Tokumura A, Terao J, Suzuki A. Rate constants for quenching singlet oxygen and activities for inhibiting lipid peroxidation of carotenoids and
$\alpha$ -tocopherol in liposomes. Lipids 33: 751-756 (1998) https://doi.org/10.1007/s11745-998-0266-y - Krinsky NI, Yeum KJ. Carotenoid-radical interactions. Biochem. Bioph. Res. Co. 305: 754-760 (2003) https://doi.org/10.1016/S0006-291X(03)00816-7
- Mortensen A, Skibsted LH, Sampson J, Rice-Evans C, Everett SA. Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants. FEBS Lett. 418: 91-97 (1997) https://doi.org/10.1016/S0014-5793(97)01355-0
-
Terao J. Antioxidant activity of
$\beta$ -carotene-related carotenoids in solution. Lipids 24: 659-661 (1989) https://doi.org/10.1007/BF02535085 - Lim BP, Nagao A, Terao J, Tanaka K, Suzuki T, Takama K. Antioxidant activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation. Biochim. Biophys. Acta 1126: 178-184 (1992) https://doi.org/10.1016/0005-2760(92)90288-7
- Goto S, Kogure K, Abe K, Kimata Y, Kitahama K, Yamashita E, Terada H. Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antiperoxidative activity of the carotenoid astaxanthin. Biochim. Biophys. Acta 1512: 251-258 (2001) https://doi.org/10.1016/S0005-2736(01)00326-1
-
Matsushita Y, Suzuki R, Nara E, Yokoyama A, Miyashita K. Antioxidant activity of polar carotenoids including astaxanthin-
$\beta$ -glucoside from marine bacterium on PC liposomes. Fisheries Sci. 66: 980-985 (2000) https://doi.org/10.1046/j.1444-2906.2000.00155.x - Lawlor SM, O'Brien NM. Astaxanthin: Antioxidant effects in chicken embryo fibroblasts. Nutr. Res. 15: 1695-1704 (1995) https://doi.org/10.1016/0271-5317(95)02040-9
-
Hill TJ, Land EJ, McGarvey DJ, Schalch W, Tinkler JH, Truscott TG. Interaction between carotenoids and the
$CCI_3O_2{^.}$ radical. J. Am. Chem. Soc. 117: 8322-8326 (1995) https://doi.org/10.1021/ja00137a004 - Nomura T, Kikuchi M, Kubodera A, Kawakami Y. Proton-donative antioxidant activity of fucoxanthin with 1, 1-diphenyl-2-picrylhydrazyl (DPPH). Biochem. Mol. BioI. Int. 42: 361-370 (1997) https://doi.org/10.1080/15216549700202761
- Nishino H. Cancer prevention by carotenoids. Mutat. Res. 402: 159-163 (1998) https://doi.org/10.1016/S0027-5107(97)00293-5
- Yan X, Chuda Y, Suzuki M, Nagata T. Fucoxanthin as the major antioxidant in Hijikia fusiformis, a common edible seaweed. Biosci. Biotech. Bioch. 63: 605-607 (1999) https://doi.org/10.1271/bbb.63.605
- Conn PF, SchaIch W, Truscott TG The singlet oxygen and carotenoid interaction. J. Photochem. Photobiol. B. 11: 41-47 (1991) https://doi.org/10.1016/1011-1344(91)80266-K
- Miller NJ, Sampson J, Candeias LP, Bramley PM, Rice-Evans CA. Antioxidant activities. of carotenes and xanthophylls. FEBS Lett. 384: 240-242 (1996) https://doi.org/10.1016/0014-5793(96)00323-7
- Murakami A, Nakashima M, Koshiba T, Maoka T, Nishino H, Yano M, Sumida T, Kim OK, Koshimizu K, Ohigashi H. Modifying effects of carotenoids on superoxide and nitric oxide generation from stimulated leukocytes. Cancer Lett. 149: 115-123 (2000) https://doi.org/10.1016/S0304-3835(99)00351-1
- Sugawara T, Baskaran V, Tsuzuki W, Nagao A. Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice. J. Nutr. 132: 946-951 (2002) https://doi.org/10.1093/jn/132.5.946
- Sachindra NM, Sato E, Maeda H, Hosokawa M, Niwano Y, Kohno M, Miyashita K. Radical scavenging and singlet oxygen quenching activity of marine carotenoid fucoxanthin and its metabolites. J. Agr. Food Chem. 55: 8516-8522 (2007) https://doi.org/10.1021/jf071848a
- Shon MY, Kim TH, Sung NJ. Antioxidants and free radical scavenging activity of Phellinus baumii (Phellinus of Hymenochaetaceae) extracts. Food Chem. 82: 593-597 (2003) https://doi.org/10.1016/S0308-8146(03)00015-3
- Roginsky V, Lissi EA. Review of methods to determine chainbreaking antioxidant activity in food. Food Chem. 92: 235-254 (2005) https://doi.org/10.1016/j.foodchem.2004.08.004
- Bertram JS, Vine AL. Cancer prevention by retinoids and carotenoids: Independent action on a common target. Biochim. Biophys. Acta 1740: 170-178 (2005) https://doi.org/10.1016/j.bbadis.2005.01.003
- Beta Carotene Cancer Prevention Study Group. The AlphaTocopherol. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. New Engl. J. Med. 330: 1029-1035 (1994) https://doi.org/10.1056/NEJM199404143301501
- Omenn GS, Goodman GE, Thomquist MD, Balmes J, Cullen MR, Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart S, Hammar S. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. New Engl. J. Med. 334: 1150-1155 (1996) https://doi.org/10.1056/NEJM199605023341802
- Tanaka T, Morishita Y, Suzui M, Kojima T, Okumura A, Mori H. Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis 15: 15-19 (1994) https://doi.org/10.1093/carcin/15.1.15
- Tanaka T, Makita H, Ohnishi M, Mori H, Satoh K, Hara A. Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin, and canthaxanthin. Cancer Res. 55: 4059-4064 (1995)
- Tanaka T, Kawamori T, Ohnishi M, Makita H, Mori H, Satoh K, Hara A. Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls, astaxanthin, and canthaxanthin during the postinitiation phase. Carcinogenesis 16: 2957-2963 (1995) https://doi.org/10.1093/carcin/16.12.2957
- Kurihara H, Koda H, Asami S, Kiso Y, Tanaka T. Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress. Life Sci. 70: 2509-2520 (2002) https://doi.org/10.1016/S0024-3205(02)01522-9
- Kozuki Y, Miura Y, Yagasaki K. Inhibitory effects of carotenoids on the invasion of rat ascites hepatoma cells in culture. Cancer Lett. 151: 111-115 (2000) https://doi.org/10.1016/S0304-3835(99)00418-8
- Jyonouchi H, Sun S, Iijima K, Gross MD. Antitumor activity of astaxanthin and its mode of action. Nutr. Cancer 36: 59-65 (2000) https://doi.org/10.1207/S15327914NC3601_9
- Yamamoto I, Maruyama H. Effect of dietary seaweed preparations on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats. Cancer Lett. 26: 241-251 (1985) https://doi.org/10.1016/0304-3835(85)90047-3
- Yamamoto I, Maruyama H, Moriguchi M. The effect of dietary seaweeds on 7, 12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats. Cancer Lett. 35: 109-118 (1987) https://doi.org/10.1016/0304-3835(87)90033-4
- Okuzumi J, Nishino H, Murakoshi M, Iwashima A, Tanaka Y, Yamane T, Fujita Y, Takahashi T. Inhibitory effects offucoxanthin, a natural carotenoid, on N-myc expression and cell cycle progression in human malignant tumor cells. Cancer Lett. 55: 75-81 (1990) https://doi.org/10.1016/0304-3835(90)90068-9
- Okuzumi J, Takahashi T, Yamane T, Kitao Y, Inagake M, Ohya K, Nishino H, Tanaka Y. Inhibitory effects of fucoxanthin, a natural carotenoid, on N-ethyl-N'-nitro-N-nitrosoguanidine-induced mouse duodenal carcinogenesis. Cancer Lett. 68: 159-168 (1993) https://doi.org/10.1016/0304-3835(93)90142-V
- Kotake-Nara E, Kushiro M, Zhang H, Sugawara T, Miyashita K, Nagao A. Carotenoids affect proliferation of human prostate cancer cells. J. Nutr. 131: 3303-3306 (2001) https://doi.org/10.1093/jn/131.12.3303
- Kotake-Nara E, Asai A, Nagao A. Neoxanthin and fucoxanthin induce apoptosis in PC-3 human prostate cancer cells. Cancer Lett. 220: 75-84 (2005) https://doi.org/10.1016/j.canlet.2004.07.048
- Hosokawa M, Wanezaki S, Miyauchi K, Kurihara H, Kohno H, Kawabata J, Odashima S, Takahashi K. Apoptosis inducing effect of fucoxanthin on human leukemia cell line HL-60. Food Sci. Technol. Res. 5: 243-246 (1999) https://doi.org/10.3136/fstr.5.243
-
Hosokawa M, Kudo M, Maeda H, Kohno H, Tanaka T, Miyashita K. Fucoxanthin induces apoptosis and enhances the antiproliferative effect of the PPAR
$\gamma$ ligand, troglitazone, on colon cancer cells. Biochim. Biophys. Acta 1675: 113-119 (2004) https://doi.org/10.1016/j.bbagen.2004.08.012 - Cohen GM. Caspases: The executioners of apoptosis. Biochem. J. 326: 1-16 (1997) https://doi.org/10.1042/bj3260001
- Konishi I, Hosokawa M, Sashima T, Kobayashi H, Miyashita K. Halocynthiaxanthin and fucoxanthinol isolated from Halocynthia roretzi induce apoptosis in human leukemia, breast and colon cancer cells. Comp. Biochem. Physiol. 142: 53-59 (2006) https://doi.org/10.1016/j.cbpc.2005.10.005
- Dulloo AG, Samec S. Uncoupling proteins: Their roles in adaptive thermogenesis and substrate metabolism reconsidered. Brit. J. Nutr. 86: 123-139 (2001) https://doi.org/10.1079/BJN2001412
- Lowell BB, S-Susullc V, Hamann A, Lawltts, JA, Himms-Hagen J, Boyer BB, Kozak LP, Flier JS. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 366: 740-742 (1993) https://doi.org/10.1038/366740a0
- Serra F, Bonet ML, Puigserver P, Oliver J, Palou A. Stimulation of uncoupling protein 1 expression in brown adipocytes by naturally occurring carotenoids. Int. J. Obesity 23: 650-655 (1999) https://doi.org/10.1038/sj.ijo.0800897
- Maeda H, Hosokawa M, Sashima T, Funayama K, Miyashita K. Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCPl expression in white adipose tissues. Biochim. Bioph. Res. Co. 332: 392-397 (2005) https://doi.org/10.1016/j.bbrc.2005.05.002
- Maeda H, Hosokawa M, Sashima T, Miyashita K. Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/ diabetic KK-N mice. J. Agr. Food Chem. 55: 7701-7706 (2007) https://doi.org/10.1021/jf071569n
- Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Cire. Res. 96: 939-949 (2005) https://doi.org/10.1161/01.RES.0000163635.62927.34
- Hotamisligil GS. Inflammation and metabolic disorders. Nature 444: 860-867 (2006) https://doi.org/10.1038/nature05485
- Matsuzawa Y. The metabolic syndrome and adipocytokines. FEBS Lett. 580: 2917-2921 (2006) https://doi.org/10.1016/j.febslet.2006.04.028
- Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Invest. 116: 1784-1792 (2006) https://doi.org/10.1172/JCI29126
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-
$\alpha$ : Direct role in obesity-linked insulin resistance. Science 259: 87-91 (1993) https://doi.org/10.1126/science.7678183 -
Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BW. Increased adipose tissue expression of tumor necrosis factor-
$\alpha$ in human obesity and insulin resistance. J. Clin. Invest. 95: 2409-2015 (1995) https://doi.org/10.1172/JCI117936 - Kitagawa Y, Bujo H, Takahashi K, Shibasaki M, Ishikawa K, Yagui K, Hashimoto N, Noda K, Nakamura T, Yano S, Saito Y. Impaired glucose tolerance is accompanied by decreased insulin sensitivity in tissues of mice implanted with cells that overexpress resistin. Diabetologia 47: 1847-1853 (2004) https://doi.org/10.1007/s00125-004-1530-4
- Hu E, Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J. BioI. Chem. 271: 10697-10703 (1996) https://doi.org/10.1074/jbc.271.18.10697
- Shiratori K, Ohgami K, Ilieva I, Jin XH, Koyama Y, Miyashita K, Yoshida K, Kase S, Ohno S. Effects of fucoxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Exp. Eye Res. 81: 422-428 (2005) https://doi.org/10.1016/j.exer.2005.03.002
- Bhattacherjee P, Williams RN, Eakins KE. A comparison of the ocular anti-inflammatory activity of steroidal and nonsteroidal compounds in the rat. Invest. Ophth. Vis. Sci. 24: 1143-1146 (1983)
- Matsuno T, Ookubo M, Nishizawa T, Shimizu I. Carotenoids of sea squirts. I. New marine carotenoids, halocynthiaxanthin, and mytiloxanthinone from Halocynthia roretzi. Chem. Pharm. Bull. 32:4309-4315 (1984) https://doi.org/10.1248/cpb.32.4309
- Konishi I, Hosokawa M, Sashima T, Maoka T, Miyashita K. Suppressive effects of alloxanthin and diatoxanthin from Halocynthia roretzi on the LPS-induced expression of proinflammatory genes in RAW264.7 cells. J. Oleo. Sci. 57: 181-89 (2008) https://doi.org/10.5650/jos.57.181
- Burger D, Dayer JM, Palmer G, Gabay C. Is IL-1 a good therapeutic target in the treatment of arthritis? Best Pract. Res. Cl. Rh. 20: 879-896 (2006) https://doi.org/10.1016/j.berh.2006.06.004
- Ziegler-Heitbrock HW. Molecular mechanism in tolerance to lipopolysaccharide. J. Inflamm. 45: 13-26 (1995)