Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지

Effect of Hwangryunhaedok-tang Pharmacopuncture at $CV_{17}$(Jeonjung : 膻中) for Mental Stress on Short-term Analysis of Heart Rate Variability

전중(膻中)($CV_{17}$) 황련해독탕약침(黃連解毒湯藥鍼)이 정신적 스트레스를 가한 성인의 심박 변이도에 미치는 영향

  • Cho, Seong-Yeun (Dept. of Acupuncture & Moxibustion, Kangnam Kyung Hee Korean Hospital, Kyung Hee University) ;
  • Ha, Seon-Yun (Dept. of Acupuncture & Moxibustion, Kangnam Kyung Hee Korean Hospital, Kyung Hee University) ;
  • Jang, Jin-Young (Dept. of Acupuncture & Moxibustion, Kangnam Kyung Hee Korean Hospital, Kyung Hee University) ;
  • Nam, Sang-Soo (Dept. of Acupuncture & Moxibustion, Kangnam Kyung Hee Korean Hospital, Kyung Hee University) ;
  • Kim, Yong-Suk (Dept. of Acupuncture & Moxibustion, Kangnam Kyung Hee Korean Hospital, Kyung Hee University)
  • 조성연 (경희대학교 강남경희한방병원 침구과) ;
  • 하선윤 (경희대학교 강남경희한방병원 침구과) ;
  • 장진영 (경희대학교 강남경희한방병원 침구과) ;
  • 남상수 (경희대학교 강남경희한방병원 침구과) ;
  • 김용석 (경희대학교 강남경희한방병원 침구과)
  • Published : 2009.10.20
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : The purpose of this study was to assess the effect of Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$ for reducing mental stress using power spectrum analysis of the heart rate variability(HRV). Methods : 30 healthy volunteers(control group: 15, experimental group: 15) participated in this study. After instrumentation and 5-minutes rest period, mental stress by operation was provided for 5-minutes. HRV was recorded before and after the mental stress. And then the control group rested for 15-minutes. The experimental group was injected Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$ and rested for 15-minutes. And then HRV was recorded. Results : In simple rest group, LF norm and HF norm showed a significant change after mental stress. In pharmacopuncture group, LF norm, HF norm and LF/HF showed a significant change after mental stress. But there were no significant difference between two groups(p>0.05). In pharmacopuncture group, LF norm, HF norm and LF/HF showed a significant change after pharmacopuncture injection. There were significant difference between two groups(p<0.01). Conclusions : The result suggests that Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$(Jeonjung) can regulate and prevent the alteration of autonomic nerve system due to mental stress.

Keywords

References

  1. 안상우 등 스트레스의 한의요법에 관한 연구. 한국한의학연구원 연구보고서. 1997.
  2. Holly R. Impact of acute mental stress on sympathetic nerve activity and regional blood flow in advanced heart failure. Circulation. 1997 ; 96 ; 1835-42. https://doi.org/10.1161/01.CIR.96.6.1835
  3. Kamath MV, Fallen EL. Power spectral analysis of heart rate variability : a noninvasive signature of cardiac autonomic function. Crit Rev Biomed Eng. 1993 ; 21(3) : 2445-311.
  4. 김완희. 한의학원론. 서울 : 성보사. 1990 : 161-2.
  5. 吉利和. 內科診斷學. 서울 : 第一醫學社. 1994 : 277-90.
  6. 李珩九, 鄭昇杞. 東醫肺系內科學. 서울 : 아트동방. 1996 : 105-7, 310, 324.
  7. 이혜정. 약침학 개론 및 임상. 서울 : 일중사. 1999 : 61-2, 76-9, 95.
  8. 안영기. 경혈학총서. 서울 : 성보사. 1986 : 672, 680-1, 702-3.
  9. 전국한의과대학 침구경혈학교실 편저, 침구학(상). 파주 : 집문당. 2008 : 308-9.
  10. Holly R. Middlekauff, Jun Liang Yu and Kakit hui. Acupuncture on reflex response to mental stress in humans. Am J Physiol Regulatory Integrative Comp Physiol. 2001 ; 280 : R1462-8.
  11. 우종민. 일차진료에서의 직장인 스트레스 대처법. 가정의학회지. 2005 ; 26 : 375-83.
  12. Jain, Burg, Soufer & Zaret. Prognostic implications of mental stress-induced silent left ventricular dysfunction in patients with stable angina pectoris. The American Journal of Cardiology. 1995 : 76, 31-5. https://doi.org/10.1016/S0002-9149(99)80796-6
  13. Porges SW. Vagal tone : a physiologic marker of stress vulnerability. Pediatrics. 1992 : 90, 498-504.
  14. 조정진. 직무 스트레스의 심혈관계 질환. 가정의학회지. 2002 ; 23(7) : 841-54.
  15. Akselrod S, Gordon DJ, Madwed B. Power spectrum analysis of heart rate fluctuation, a quantitative prove of beat to beat cardiovascular control. Science. 1981 ; 213 : 220-2. https://doi.org/10.1126/science.6166045
  16. Pomeranz B, Macauly RJ, Caudill MA, Kutz I, Adam D, Gordon D, Kilborn KM, Bargar AC, Shannon DC, Cohen RJ et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol. 1985 ; 248(1 Pt 2) : 151-3.
  17. Malik M, Xia R, Odemuyiwa O, Staunton A, Poloniecki J, Camm AJ. Influence of the recognition artefact in automatic analysis of long term electrocardiograms on time-domain measurement of heart rate variability. Med Biol Eng Comput, 1993 ; 31(5) : 539-44. https://doi.org/10.1007/BF02441992
  18. 양동훈, 박영배. 맥파와 심박변이도의 상관성 연구. 대한한의학진단학회지. 2000 ; 10(2) : 104-20.
  19. Korpelainen JT, Huikuri HV, Sotaniemi KA, Myllyla VV. Abnormal heart rate variability reflecting autonomic dysfunction in brainstem infarction. Acta Neurol Scand. 1996 ; 94(5) : 337-42. https://doi.org/10.1111/j.1600-0404.1996.tb07076.x
  20. 王燾. 外臺秘要方. 태성문화사. 1992 : 47.
  21. 동양의학대사전편찬위원회. 동양의학대사전 11. 서울 : 대한교과서(주). 1999 : 478-9.
  22. 대한약침학회. 약침요법시술지침서. 서울 : 한성인쇄. 2000 : 120-25, 180-202.
  23. 신길조, 조기호, 김영석, 배형섭, 이경섭. 黃連解毒 湯藥의 약침제제의 안정성 및 효능에 관한 연구. 경희한의대논문집. 1994 ; 17(1) : 85-119.
  24. 김은선, 박치상, 박창국. 黃連解毒湯과 온청음이 고혈압 및 고지혈증에 미치는 영향. 대한한의학회지. 1999 ; 20(1) : 185-96.
  25. 崔殷圭, 具炳壽. 黃連解毒湯藥鍼의 機能性頭痛 治療 效果에 대한 臨床的 考察. 동의신경정신과학회지. 2000 ; 11(1) : 75-81.
  26. 설현, 육태한. 肩井穴 黃連解毒湯藥鍼이 심박변이율에 미치는 영향. 대한침구학회지. 2004 ; 21(6) : 37-50.
  27. 강인, 문자영, 임명장, 조재희, 이효은. 급성기 족관절 염좌 환자에 대한 치료방법에 따른 효과 비교 연구. 대한침구학회지. 2008 ; 25(5) : 89-95.
  28. 동양의학대사전편찬위원회. 동양의학대사전 8. 서울 : 대한교과서(주). 1999 : 608.
  29. 대한약침학회 編譯. 약침제제와 임상응용. 대한약침학회. 서울. 1997 : 3-5.
  30. 동양의학대사전편찬위원회. 동양의학대사전 6. 서울 : 대한교과서(주). 1999 : 474.
  31. Montano N, Ruscone TG, Porta A, Lombardi F, Pagani M, Malliani A. Power spectarl analysis of heart rate variability to assess the changes in sympatho-vagal balince during graded ortho-static tilt. Circulation. 1994 ; 90(4) : 1826-31. https://doi.org/10.1161/01.CIR.90.4.1826
  32. Nis Hijortskov. etx. The effect of mental stress on heart rate variability and blood pressure during computer work. Eur J Appl Physiol. 2004 ; 92 : 84-9. https://doi.org/10.1007/s00421-004-1055-z
  33. 김정신, 황욱, 배기태, 남상수, 김용석. 少府($HT_8$) 刺針이 정신적 스트레스를 가한 성인의 심박변이도에 미치는 영향. 대한침구학회지. 2004 ; 21(5) : 227-39.
  34. Kazushi N, Hidetoshi M, Keishi Y, Kazuhiro Y. Decreased heart rate by acupuncture stimulation in humans via facilitation of cardiac vagal activity and suppression of cardiac sympathetic nerve. Neuroscience Letters. 1997 ; 227 : 165-8. https://doi.org/10.1016/S0304-3940(97)00337-6
  35. Zengyong Li, Chengtao Wang, Arthur FT Mak, Danieal HK Chow. Effects of acupuncture on jeart rate variability in normal subjects under fatigue and non-fatigue state. Eur J Appl Physiol. published online(20 May 2005).
  36. ST Huang, GY Chen, HM Lo, JG Lin, YS Lee, CD Duo. Increase in the vagal modulation by acupuncture at Neiguan point on the healthy subjects. The Am J Chinese Med. 2005 ; 33(1) : 157-64. https://doi.org/10.1142/S0192415X0500276X
  37. 장보형, 이정희, 문경숙, 김진원, 권오섭. 이침 요법이 정신적 스트레스를 가한 성인의 심박변이도에 미치는 영향. 대한침구학회지. 2005 ; 22(6) : 173-80.