Nuclear Medicine and Molecular Imaging

The Korean Society of Nuclear Medicine (대한핵의학회)
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Brown Tumor Shown Flare Phenomenon On Bone Scan After Parathyroidectomy

부갑상샘절제술 이후 뼈스캔에서 발적 현상을 나타낸 갈색종

  • Shin, Kwang-Ho (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Seol-Hoon (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Baek, So-Ra (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Chae, Sun-Young (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Koh, Jung-Min (Department of Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Jae-Seung (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Moon, Dae-Hyuk (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Ryu, Jin-Sook (Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 신광호 (울산의대 서울아산병원 핵의학과) ;
  • 박설훈 (울산의대 서울아산병원 핵의학과) ;
  • 백소라 (울산의대 서울아산병원 핵의학과) ;
  • 채선영 (울산의대 서울아산병원 핵의학과) ;
  • 고정민 (울산의대 서울아산병원 내분비내과) ;
  • 김재승 (울산의대 서울아산병원 핵의학과) ;
  • 문대혁 (울산의대 서울아산병원 핵의학과) ;
  • 류진숙 (울산의대 서울아산병원 핵의학과)
  • Published : 2009.10.31
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Abstract

Brown tumor is the benign bone lesion consists of woven bone and fibrous tissue without matrix, which develop due to chronic excessive osteoclastic activity such as hyperparathyroidism. Usually they appear with normal uptake or occasionally focally increased uptake on bone scan. We present a case with brown tumor shown more increased uptake and more number of lesions on bone scan after parathyroidectomy, and lesser increased uptake on serial bone scans without any other treatment through several months. This finding is thought to be similar to 'flare phenomenon' which is occasionally seen after treatment of metastatic bone lesions of malignant cancer, and may represent curative process of brown tumor with rapid normal bone formation.

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