Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Global Cerebral Ischemia in a Beagle Dog

비글견에서 발생한 전반적 대뇌허혈

  • Choi, Ho-Jung (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Choi, Soo-Young (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • An, Ji-Young (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • O, I-Se (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Jeong, Seong-Mok (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Cho, Sung-Whan (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lee, Young-Won (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University)
  • 최호정 (충남대학교 수의과대학.동물의과학연구소) ;
  • 최수영 (충남대학교 수의과대학.동물의과학연구소) ;
  • 안지영 (충남대학교 수의과대학.동물의과학연구소) ;
  • 오이세 (충남대학교 수의과대학.동물의과학연구소) ;
  • 정성목 (충남대학교 수의과대학.동물의과학연구소) ;
  • 조성환 (충남대학교 수의과대학.동물의과학연구소) ;
  • 이영원 (충남대학교 수의과대학.동물의과학연구소)
  • Published : 2009.02.27
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Abstract

Global cerebral ischemia occurs commonly in patients who have a variety of clinical conditions including cardiac arrest and shock. Cerebral ischemia results in a rapid depletion of energy stores that triggers resulting in excitotoxic death. Imaging studies of the brain with computed tomography(CT) or magnetic resonance imaging(MRI) are necessary to confirm the clinical neurolocalization, identify any associated mass effect, and rule out other causes of focal brain disorders. Cardiopulmonary arrest was occurred by propofol anesthesia in a 1 year old, intact female Beagle dog. After successful cardiopulmonary resuscitation was performed within 5 minutes, clinical signs such as vocalization, paddling, opisthotonus and seizure were represented. At the 12th day, CT and MRI examinations of the brain were performed to evaluate the brain. After euthanasia, histopathologic examination was performed. On transverse image of CT, lesions appeared as a hypodense in the right dorsal surface of the frontal lobe and level of optic canal, and dorsomedial surface of occipital lobe of cerebrum. No contrast enhancement was represented following intravenous contrast administration. On MR images of brain, the lesions were seen as a hyperintense on T2-weighted(T2W) images and a isointense or mild hypointense on T1-weighted(T1W) images. Hyperintense lesions both T2W and T1W images were observed at the surrounding cerebral sulcus. There was no significant signal changes on contrast T1WI. Histopathologic examination after euthanasia revealed that the lesion was necrosis of the cerebral cortex caused by cerebral ischemia.

Keywords

References

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