한국간담췌외과학회지 (Annals of Hepato-Biliary-Pancreatic Surgery)

  • 제13권1호
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  • Pages.49-53
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  • 2009
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  • 2508-5778(pISSN)
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  • 2508-5859(eISSN)
한국간담췌외과학회 (The Korean Association of Hepato-Biliary-Pancreatic Surgery)
권호 표지

바터팽대부암의 치료성적

The Outcomes of Curative Resection for Ampulla of Vater Cancer

  • Kim, Yong-Bae (Department of Surgery, Korea Institute of Radiological and Medical Science) ;
  • Kim, Sang-Bum (Department of Surgery, Korea Institute of Radiological and Medical Science) ;
  • Cho, Eung-Ho (Department of Surgery, Korea Institute of Radiological and Medical Science) ;
  • Choi, Dong-Wook (SungKyunKwan University School of Medicine) ;
  • Bang, Ho-Yoon (Department of Surgery, Korea Institute of Radiological and Medical Science) ;
  • Lee, Jong-Inn (Department of Surgery, Korea Institute of Radiological and Medical Science) ;
  • Moon, Nan-Mo (Department of Surgery, Korea Institute of Radiological and Medical Science)
  • 발행 : 2009.03.25

⟨ 이전 논문 다음 논문 ⟩

초록

Introduction: The prognosis of peri-ampullary cancer is poor because of its low respectability and high recurrence rate. Yet cancer of the Ampulla of Vater(AOV) has a relatively good prognosis. The aim of this study is to investigate the outcomes and to determine the factors that affect the survival rate of patients who underwent curative resection for AOV cancer. Methods: From August 1988 to January 2008, 54 patients underwent curative resection for AOV cancer. We retrospectively reviewed the clinocopathologic data. The median follow up period was 45 months. Results: Twenty-seven pancreaticoduodenectomies (PD) and 27 pyrolus-preserving pancreaticoduodenectomies (PPPD) were performed. There was no hospital mortality, but 25 out of 54 patients (47.3%) experienced postoperative complications. The 5-year overall survival (OS) rate was 53.97% and the 5-year disease free survival (DFS) rate was 51.75%. On multivariate analysis, the variables that affected the overall survival rate and the disease free survival rate was poor histologic differentiation (p<0.001). Conclusions: Although the AOV cancer is one of the periampullary cancers that have a very poor outcome, long-term survival and favorable outcomes can be achieved after a curative resection. In this study, poor-histologic differentiation was the only independent factor for a poor prognosis.

키워드

참고문헌

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