한국간담췌외과학회지 (Annals of Hepato-Biliary-Pancreatic Surgery)

  • 제13권4호
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  • Pages.215-220
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  • 2009
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  • 2508-5778(pISSN)
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  • 2508-5859(eISSN)
한국간담췌외과학회 (The Korean Association of Hepato-Biliary-Pancreatic Surgery)
권호 표지

소간세포암에서 해부학적 간절제술의 의의 및 예후

The Prognostic Significance of Anatomical Resection for Small Hepatocellular Carcinoma

  • 정진우 (영남대학교 의과대학 외과학교실) ;
  • 김홍진 (영남대학교 의과대학 외과학교실) ;
  • 윤성수 (영남대학교 의과대학 외과학교실) ;
  • 이동식 (영남대학교 의과대학 외과학교실) ;
  • 황대욱 (영남대학교 의과대학 외과학교실)
  • Jung, Jin-Woo (Department of Surgery, College of Medicine, Yeungnam University) ;
  • Kim, Hong-Jin (Department of Surgery, College of Medicine, Yeungnam University) ;
  • Yun, Sung-Su (Department of Surgery, College of Medicine, Yeungnam University) ;
  • Lee, Dong-Shik (Department of Surgery, College of Medicine, Yeungnam University) ;
  • Hwang, Dae-Wook (Department of Surgery, College of Medicine, Yeungnam University)
  • 발행 : 2009.12.31

⟨ 이전 논문 다음 논문 ⟩

초록

Purpose: There has been controversy concerning which is the best treatment method for small hepatocellular carcinoma between anatomical resection (AR) and non-anatomical resection (NAR). In this retrospective study, we investigated the outcomes of surgical resection for small hepatocellular carcinoma and the clinical results depending on the type of hepatectomy. Methods: We performed an analysis of the clinicopathologic factors of forty eight patients who underwent hepatectomy for a small (<2 cm) hepatocellular carcinoma between 1990 and 2005. The AR was defined as the resection based on the segment or lobe, as proposed by Couinaud. NAR was defined as the resection of a lesion without regard to the segmental or lobar anatomy, as proposed by Couinaud. The patients were divided into 2 groups base on the hepatectomy procedure: AR (n=24) and NAR (n=24). Results: There were no significant difference between the two groups for the general characteristics of the patients and the clinicopathologic findings, except for ICG R15. The mean ICG R15 in the AR and NAR groups was $11.8{\pm}6.9$ and $22.4{\pm}15.6$, respectively, The NAR group had significantly higher ICG R15 values. The cumulative 1, 3 and 5 year overall survival rates in the AR and NAR groups were 95.8%, 68.2% and 61.3%, and 76.6%, 59.0% and 52.5%, respectively. The cumulative overall survival rate and the mean 5 year disease free survival rate in the AR group (69.8%) were higher than those of the NAR group (45.8%). However, there was no statistically significant difference. Conclusion: Depending on the surgical results of this study, there was no statistically significant difference in the outcomes between the AR and NAR groups.

키워드

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