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The Enhancing Effect of Atopic Dermatitis by cosmetics containing estern medical herbs

한방소재 화장품의 아토피 피부염 개선 효과

  • Published : 2009.11.30

Abstract

Sixteen moderate atopic dermatitis patients were treated with applying toner and cream using estern medical herbs[Estern medical complex(Radix Glycyrrhizae, Radix Angelicae Dahuricae, Rhizoma Ligustici Chuanxiong, Fructus ponciri Seu Aurantii Immaturus, Radix Rehmanniae Praeparata, Radix Puerariae, Rhizoma Corydalis), Cypress, Green tea, Radix Astragali, Red ginseng, Syrup ferment, Apple ferment filtrate] on the atopic area 2-3 times per day for 6 weeks. After 6 weeks of study, the result was a decrease in SCORAD index($26.9{\pm}11.8$ to $14.9{\pm}9.7$(p<0.05)), IgE($641.9{\pm}1294.6$ to $565.8{\pm}1076.8$), Eosinophil count($246.7{\pm}203.5$ to $203.3{\pm}130.7$(p<0.05)) and TEWL($16.7{\pm}5.1$ to $15.4{\pm}8.7$(p<0.05)). And skin hydration was increased($36.6{\pm}10.0$ to $44.0{\pm}10.3$(p<0.01)) maintaining skin pH level. The patient;s and physician's global assessment also improved. Therefore, estern medical herbs may play a role in treatment of atopic dermatitis.

한방소재를 이용한 화장품이 아토피피부염을 개선하는지를 알아보고자, 중등증의 아토피 피부염환자 16명을 대상으로, 진경한방컴플렉스(감초, 백지, 작약, 지실, 천궁, 갈근, 현호색), 편백수, 녹차, 황기, 홍삼, 당밀발효액, 사과 발효여과물이 함유된 화장수와 크림을 하루에 3회 피부염병변에 6주간 도포하도록 하였다. 그 결과 SCORAD 지수는 $26.9{\pm}11.8$에서 $14.9{\pm}9.7$로 감소(p<0.05), Total IgE(IU/mL)는 $641.9{\pm}1294.6$에서 $565.8{\pm}1076.8$로 감소, Eosinophil의 수(ug/dL)는 $246.7{\pm}203.5$에서 $203.3{\pm}130.7$로 감소하였다(p<0.05). 피부수분함유량은 $36.6{\pm}10.0$에서 $44.0{\pm}10.3$로 증가(p<0.01), 경피수분손실량(g/h/$m^2$)은 $16.7{\pm}5.1$에서 $15.4{\pm}8.7$로 감소(p<0.05)하였으며, 피부 pH는 약산성을 유지하였다. 또한 의사 및 환자의 총괄유효성 평가도 증가되었다.

Keywords

References

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