Bulletin of the Korean Chemical Society

  • 제30권5호
  • /
  • Pages.1147-1151
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  • 2009
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  • 0253-2964(pISSN)
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  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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Synthesis of 3'(β)-C-methyl Carbodine Analogues as Potential Anti-HCV Agents

  • Li, Hua (BK21- Project Team, College of Pharmacy, Chosun University) ;
  • Baik, Young-Chan (Hawon Pharmaceuticals Co.,) ;
  • Hong, Joon-Hee (BK21- Project Team, College of Pharmacy, Chosun University)
  • 발행 : 2009.05.20
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초록

The synthetic route of novel 3′-C-methyl carbodine analogue is described. The construction of tertiary alcohol at 3′- position of carbodine analogues was successfully made via sequential [3,3]-sigmatropic rearrangement, ring-closing metathesis (RCM) and stereoselective dihydroxylation reactions starting from ethyl glycolate.

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  4. Design and Synthesis of Novel Carbocyclic Versions of 2′-spirocyclopropyl Ribonucleosides as Potent Anti-HCV Agents vol.30, pp.6, 2009, https://doi.org/10.1080/15257770.2011.587490