잔소리졸 함유 껌의 치태 및 치은염 억제 효과

Effect of Curcuma Xanthorrhiza containing gum on reduction of the plaque and the gingivitis

  • 박정철 (연세대학교 치과대학 치주과학교실) ;
  • 송지은 (연세대학교 치과대학 치주과학교실) ;
  • 권영진 (해태제과식품(주) 중앙연구소) ;
  • 신용목 (해태제과식품(주) 중앙연구소) ;
  • 황재관 (연세대학교 생명공학과) ;
  • 김종관 (연세대학교 치과대학 치주과학교실)
  • Park, Jeong-Cheol (Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University) ;
  • Song, Ji-Eun (Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University) ;
  • Gwon, Yeong-Jin (R&D institute, Haitai Co.) ;
  • Sin, Yong-Mok (R&D institute, Haitai Co.) ;
  • Hwang, Jae-Gwan (Department of Biotechnology, Yonsei University) ;
  • Kim, Jong-Gwan (Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University)
  • 발행 : 2008.05.01

초록

The purpose of the present study was to determine the effect of a chewing gum containing 70% xylitol and 0.23% Curcuma xanthorrhiza extract to remove dental plaque and reduce gingivitis when used as a supplement to daily toothbrushing for 3 weeks. The study group consisted of 75 adults with moderate gingvitis. Participants were divided into 3 groups(contol 1 group - Gum base, contol 2 group - 70% Xylitol, experiment group - 70% xylitol and 0.23% xanthorrhizol) and instructed to chew the study gum for 3 times daily for 3 weeks in addition to regular daily toothbrushing. Chewing xylitol/xanthorrhizol gum significantly reduced plaque index with significant difference by week 3(p<0.01). Gingival index and bleeding on probing were decreased in xy/ Curcuma xanthorrhiza extract group by 35.9% and 31.65% each in the same period. No adverse effects on the oral tissues were observed in any of the participants for the duration of the study. In conclusion, regular use of a chewing gum containing 70% xylitol and 0.23% Curcuma xanthorrhiza extract appears safe and effective for the removal of dental plaque and reduction of gingivitis when used in conjunction with daily toothbrushing.

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