The Journal of the Korean dental association (대한치과의사협회지)
- Volume 46 Issue 9
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- Pages.563-573
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- 2008
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- 0376-4672(pISSN)
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- 2713-7961(eISSN)
Effects of Simvastatin on osteogenesis of rat osteoblast-like cells, UMP-106
Simvastatin이 UMR-106 세포의 조골세포 형성에 미치는 영향
- Hwang, Eui-Kwan (Dept. of Oral and Maxillofacial Surgery, Graduate School of Denistry, Kyunghee University) ;
- Ryu, Dong-Mok (Dept. of Oral & Maxillofacial Surgery, Professional Graduate School of Denistry, Kyunghee University) ;
- Jee, Yu-Jin (Dept. of Oral & Maxillofacial Surgery, Professional Graduate School of Denistry, Kyunghee University) ;
- Lee, Deok-Won (Dept. of Oral and Maxillofacial Surgery, Graduate School of Denistry, Kyunghee University) ;
- Lee, Hyun-Woo (Dept. of Dental Pharmacology, Professional Graduate School of Denistry, Kyunghee University)
- 황의관 (경희대학교 일반대학원 치의학과 구강악안면외과학) ;
- 류동목 (경희대학교 치의학전문대학원 구강악안면외과학교실) ;
- 지유진 (경희대학교 치의학전문대학원 구강악안면외과학교실) ;
- 이덕원 (경희대학교 일반대학원 치의학과 구강악안면외과학) ;
- 이현우 (경희대학교 치의학전문대학원 치과약리학교실)
- Published : 2008.09.01
Abstract
Purpose : The purpose of this study is to investigate the effects of Simvastain, which is HMG-CoA reductase inhibitor, on proliferation and differentiation of osteoblast. Materials & Methods : Twenty-four cell culture plates containing essential medium were seeded with UMR-106 cell lines, at density of 5 x